Navigation Links
Alfacell Reports Fiscal Fourth Quarter and Full Year 2008 Financial Results
Date:10/14/2008

. Based on the current expected level of receipts and expenditures, the company believes that its cash and cash equivalents are sufficient to support its activities into the fourth quarter of fiscal year 2009. The company will be eligible to receive a minimum milestone payment of $20 million from its U.S. partner, Strativa Pharmaceuticals, in the event that the planned NDA submission results in the company receiving marketing approval for ONCONASE.

Clinical/Regulatory Update

Alfacell has completed patient enrollment in a confirmatory Phase IIIb clinical trial for ONCONASE in patients suffering from unresectable malignant mesothelioma (UMM) and reached the required number of evaluable events to conduct the formal statistical analyses required to complete the final sections of the ONCONASE rolling NDA. As the company has previously reported, the results of the preliminary statistical analysis of the data did not meet statistical significance for the primary endpoint of survival in UMM. However, a statistically significant improvement in survival was seen in the treatment of UMM patients who failed one prior chemotherapy regimen, a pre-defined primary data set for this sub-group of patients in the trial, which represents a currently unmet medical need. Alfacell has requested a pre-NDA meeting with the Food and Drug Administration (FDA) to discuss the details of the planned NDA submission. The company continues to estimate that the final components of the rolling NDA will be submitted by the end of 2008, and the company plans to present the results of the Phase IIIb trial at an upcoming scientific conference in 2009.

The company has completed enrollment in its Phase I clinical trials for patients suffering from non-small cell lung cancer (NSCLC) and other solid tumors and is planning for a follow-on Phase II clinical trial in NSCLC patients that exhibit resistance to platinum based chemotherapy regimens. Initiation of patient enrollment in this tria
'/>"/>

SOURCE Alfacell Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Paper in Cell Cycle Reports Alfacells ONCONASE(R) Targets siRNA
2. Alfacell Hires Advisors to Advance Strategic Alternatives
3. Alfacell Receives NASDAQ Delisting Letter
4. Alfacell Receives NASDAQ Non-Compliance Notification
5. Alfacell Reports Financial Results for Third Quarter of Fiscal 2008
6. Alfacell Announces Retirement of Chief Executive Officer
7. Alfacell Reports Financial Results for Second Quarter of Fiscal 2008
8. Alfacell to Host Fiscal Second Quarter 2008 Financial Results Conference Call and Webcast
9. Alfacell Announces ONCONASE(R) Purchase and Supply Agreement with Scientific Protein Laboratories
10. Alfacell to Host Webinar on RNA Interference-Like Mechanics of RNase Therapeutics on Nov. 29
11. Alfacell to Host Fiscal Fourth Quarter and Year-End 2007 Financial Results Conference Call and Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... 18, 2014 American Process Inc. ... formed a partnership with researchers at Georgia Institute ... Technology, and the USDA’s Forest Products Laboratory to ... nanocellulose. Nanocellulose is a rapidly emerging high performance ... project is to replace heavy steel structures within ...
(Date:11/18/2014)... Nov. 18, 2014  Asterias Biotherapeutics, Inc. (NYSE ... emerging field of regenerative medicine, today announced that ... cells) for complete cervical spinal cord injury (SCI), ... Advanced Therapies Projects to Watch" by Elsevier Business ... this significant industry honor, which represents independent validation ...
(Date:11/16/2014)... 2014 The “Fluid Management & ... visualization systems market with an analysis and forecast ... irrigation, dialyzes, fluid warming and waste management. Along ... fluid visualization systems by applications and regions are ... was valued at $19,285.5 million in 2013 and ...
(Date:11/15/2014)... 14, 2014 The International ... today that the society’s Governing Board has grown ... Lifesciences chief scientific officer and Dr. Charles Simonton, ... Abbott Vascular. Mr. Rowe and Dr. Simonton ... development experts. , Dr. Nabil Dib, ISCTR ...
Breaking Biology Technology:American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 2American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 3Asterias Biotherapeutics Named as a "Top Advanced Therapies Projects to Watch" and Will Present at the Therapeutic Area Partnerships Conference 2Asterias Biotherapeutics Named as a "Top Advanced Therapies Projects to Watch" and Will Present at the Therapeutic Area Partnerships Conference 3Fluid Visualization Systems Market poised to reach $25,908.4 Million by 2018 - New Research Report by MarketsandMarkets 2Fluid Visualization Systems Market poised to reach $25,908.4 Million by 2018 - New Research Report by MarketsandMarkets 3Fluid Visualization Systems Market poised to reach $25,908.4 Million by 2018 - New Research Report by MarketsandMarkets 4International Society for Cardiovascular Translational Research Governing Board Adds Medical Industry Leaders 2
... Inc. , has announced it will price a forthcoming ... at $3.75 per share. , ,Proceeds from the ... 2006, will be used to support research and development ... and intellectual property protection. The Madison-based company, which has ...
... people should be outraged at getting a second-rate solution for ... what average consumers demand in almost every other product and ... across many products and services as the general metric for ... world class. , , Speed is good , ...
... University of Wisconsin-Madison , justified or otherwise, is ... the tree. It has world-class scientists and well-developed mechanisms ... but most of that commercialization takes place within a ... true. Just check the figures for per capita wages, ...
Cached Biology Technology:Damn the incumbents, and full speed ahead 2Damn the incumbents, and full speed ahead 3Damn the incumbents, and full speed ahead 4Entrepreneurship grant will build strong foundation 2Entrepreneurship grant will build strong foundation 3Entrepreneurship grant will build strong foundation 4
(Date:11/4/2014)... 4, 2014   Neurotechnology , a provider ... the latest version of its fingerprint matching algorithm ... MINEX evaluation organized by NIST. The MINEX ... the INCITS 378 fingerprint standard template format. MINEX ... tenders in the United States ...
(Date:11/3/2014)... Colorado Cancer Center study published in this ... describes the activity of a recently discovered communication ... IL-37. It has been known to limit inflammation and ... immune system: IL-37 inhibits the ability of the immune ... this mechanism that underlies IL-37,s effect on the immune ...
(Date:11/3/2014)... low birth weight and preterm birth are linked to ... Findings published in the American College of Rheumatology (ACR) ... low birth weight and pre-term babies were not at ... adults. , According to the ACR, 27 million ... clinical OA. Symptoms of OA range from mild to ...
Breaking Biology News(10 mins):Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3PNAS: From HIV to cancer, IL-37 regulates immune system 2Preterm, low birth-weight babies may need new hips in adulthood 2
... Associate Professor at The City College of New York (CCNY), have ... water so that it can be scooped up like the fat ... soup. The agent could potentially be used to recover oil lost ... Professor John said. In the laboratory, Professor John and colleagues ...
... ANN ARBOR, Mich.---When paleontologist Iyad Zalmout went looking for fossil ... come face-to-face with a significant, early primate fossil. ... what the last common ancestor of apes and monkeys may ... separate ways. Zalmout and colleagues at the University of ...
... (July 14, 2010) Rice University scientists have ... nanotubes (CNTs), a breakthrough that brings the creation of ... Nanotubes have the frustrating habit of bundling, making them ... Rice scientists led by Matteo Pasquali, a professor in ...
Cached Biology News:Fossil find puts a face on early primates 2Fossil find puts a face on early primates 3Fossil find puts a face on early primates 4Nanotubes pass acid test 2Nanotubes pass acid test 3
... The BD FACSAria cell sorter sets ... cytometry. Based on a revolutionary new ... delivers high-speed sorting and multicolor analysis. The ... sorter that incorporates a fixed-alignment cuvette flow ...
Mouse polyclonal antibody raised against a partial recombinant AGTRAP. NCBI Entrez Gene ID = 57085...
...
Mouse monoclonal antibody raised against a partial recombinant ZNF155. NCBI Entrez Gene ID = ZNF155...
Biology Products: