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Aegera Initiates Phase 2 Clinical Trial Of AEG33773 - A Small Molecule Targeting Neuropathic Pain
Date:5/6/2009

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Aegera Therapeutics is a clinical stage biotechnology company focused on developing targeted therapeutics for major unmet medical needs. Aegera has three programs in clinical development. In addition to AEG33773, Aegera is developing

    - AEG35156 targets the key anti-apoptotic protein XIAP, and is in
      multiple randomized Phase II clinical trials;
    - HGS1029(AEG40826) is a small molecule pan-IAP inhibitor in Phase 1
      development. It has demonstrated very promising preclinical activity
      and is partnered with Human Genome Sciences, Inc. (Nasdaq:  HGSI) for o
      ncology in all countries except Japan.

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2. Aegera initiates Phase 1 clinical trial of AEG33773 - A small molecule in development for diabetic neuropathic pain
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4. Aegera Therapeutics collaboration with Human Genome Sciences leads to the initiation of a Phase 1 clinical trial with lead IAP inhibitor HGS1029 and receipt of first milestone payment
5. Aegera Therapeutics phase 1/2 clinical trial results selected for oral presentation at 2008 ASH Annual Meeting
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