Navigation Links
Acumen Pharmaceuticals Regains Worldwide Rights to Anti-ADDL Antibody Therapeutics and Diagnostics for Alzheimer's Disease From Merck
Date:12/21/2011

SAN FRANCISCO, Dec. 21, 2011 /PRNewswire/ -- Acumen Pharmaceuticals announces today the termination by Merck Sharp & Dohme Corp., (formerly Merck & Co., Inc.) of a 2003 agreement, amended in 2006, under which Acumen granted Merck exclusive worldwide rights to develop and commercialize anti-ADDL antibody therapeutics and diagnostics for Alzheimer's disease.

Merck's decision to discontinue this anti-ADDL Alzheimer's program and terminate the Merck-Acumen license agreement was based on internal strategic priorities. Under the termination provisions of the agreement, Acumen regains rights licensed to Merck, and also receives certain rights to patent applications and know how generated during the term of the Agreement. Anti-ADDL antibodies have high selectivity for soluble amyloid beta oligomers versus monomeric amyloid beta peptides or insoluble amyloid beta aggregates. Acumen believes this selectivity will favorably differentiate Acumen anti- ADDL immunotherapies compared to amyloid beta immunotherapies currently in late stage clinical testing.

"Acumen is very pleased to regain worldwide rights for the development and commercialization of anti-ADDL antibody therapeutics and diagnostics," stated Grant Krafft, Acumen's Chairman and Chief Science Adviser.

Acumen's Board of Directors also announces the appointment of Franz Hefti, Ph.D. as Acumen's President and CEO. Dr. Hefti has served as a Director of Acumen since 2008 and has a distinguished record in drug development and biotechnology ventures. Dr. Hefti served as Chief Science Officer for Avid Radiopharmaceuticals, which Eli Lilly & Co. acquired in 2010 for its Alzheimer's imaging product, Amyvid™. Prior to Avid, Dr. Hefti was Executive Vice President of Drug Development for Rinat Neuroscience Corporation where he led preclinical and clinical drug development efforts for three antibody drug candidates. The success of these programs led to Pfizer's 2006 acquisition of Rinat.
'/>"/>

SOURCE Acumen Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Synergy Pharmaceuticals, Inc. Files Suit Against Ironwood Pharmaceuticals, Inc. and its Chief Scientific Officer and Senior VP of R&D, Dr. Mark G. Currie
2. Questcor Pharmaceuticals to Present at the Oppenheimer Healthcare Conference on December 13, 2011
3. TetraLogic Pharmaceuticals Announces Initiation of a Phase 1/2 Clinical Trial of TL32711 in Patients with Acute Myelogenous Leukemia (AML)
4. Convergence Pharmaceuticals Initiates Phase I Multiple Ascending Dose Study for CNV2197944
5. Keryx Biopharmaceuticals, Inc. Announces Upcoming Poster Presentations of Zerenex™ (Ferric Citrate) at the Upcoming American Society of Nephrology Kidney Week 2011 Annual Meeting
6. Access Pharmaceuticals Signs Agreement for CobaCyte® and CobOral® in RNAi Therapeutic Delivery
7. Radient Pharmaceuticals Announces Proxy Resolutions Approved at Special Meeting of Stockholders
8. Cumberland Pharmaceuticals Reports Third Quarter 2011 Financial Results
9. Optimer Pharmaceuticals Reports Third Quarter 2011 Financial Results
10. Cadence Pharmaceuticals CEO Ted Schroeder to Present at the Credit Suisse Healthcare Conference on November 9, 2011
11. Optimer Pharmaceuticals to Present at 20th Annual Credit Suisse Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... (PRWEB) January 15, 2014 Two champions ... continued their sponsorship of an annual competition for middle ... and access to, innovative STEM study. The competition presents ... TEAMS: Tests of Engineering Aptitude, Mathematics, and Sciences ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider of Notched Sound ... Patients listen to sound therapy that is tailor-made for ... to months, their tinnitus volume decreases. , AudioNotch has previously ... Notched White Noise. Now, AudioNotch is pleased to announce to ...
(Date:1/14/2014)... 2014  3D Communications, a leading provider of strategic communications services to ... events in the United States and ... Cox , JD, is returning to the firm,s Washington, ... 3D after more than two years of service as Associate Commissioner ...
(Date:1/14/2014)... 2014 iLab Solutions, the leader in core ... Director of Product Strategy. In this role, Michelle will work ... to guide in the development of iLab products. Her main ... possible benefit to the scientific community by offering the most ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Former FDA Associate Commissioner Returns To 3D Communications 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... third-party plug-in for popular embedded tool suite. , ... ... Quadros Systems, Inc., a leading supplier of configurable and scalable ... module for the RTXC Quadros RTOS is now available for ...
... on Tuesday, July 15 at 4:30 p.m. Eastern -, ... VRML ), a molecular diagnostics company, will host a ... Ueland,M.D., Principal Investigator on the submission and Associate Professor ... the keynote,speaker of the roundtable., Vermillion,s ovarian tumor ...
... 11 Signalife,Inc. (Amex: SGN ) announced ... its previously-announced merger or similar business combination with,Heart ... has been,appointed to proceed with due diligence and ... presently contemplated, a new parent,company will be established ...
Cached Biology Technology:RTXC Kernel Awareness Module from Quadros Systems Now Available for Keil Vision Debugger 2RTXC Kernel Awareness Module from Quadros Systems Now Available for Keil Vision Debugger 3RTXC Kernel Awareness Module from Quadros Systems Now Available for Keil Vision Debugger 4Vermillion to Host Live Roundtable Discussion With Principal Investigator of OVA1(TM) Submission 2Vermillion to Host Live Roundtable Discussion With Principal Investigator of OVA1(TM) Submission 3Signalife Board Approves Merger 2Signalife Board Approves Merger 3
(Date:4/17/2014)... University of Texas Medical Branch at Galveston are ... with radiation for cervical cancer should begin colorectal ... The UTMB researchers, finding a high incidence of ... with radiation, offer new recommendations that the younger ... about eight years after their initial cervical cancer ...
(Date:4/17/2014)... immune system may fight cancers and viral infections. The ... treat illness. , The research, in mice, suggests that ... specialized squads of defenders that patrol only one ... the body. , Scientists at Washington University School of ... skin and uterus each has dedicated immune cells, which ...
(Date:4/17/2014)... feature of The Proceedings of the ... April 29, raises a number of startling questions about ... us take for granted. At the end of the ... globe shifted from hunting animals and gathering fruits and ... so straightforward and yet the more scientists learn, the ...
Breaking Biology News(10 mins):Radiation therapy for cervical cancer increases risk for colorectal cancer 2Some immune cells defend only 1 organ 2Genetic study tackles mystery of slow plant domestications 2Genetic study tackles mystery of slow plant domestications 3Genetic study tackles mystery of slow plant domestications 4
... try to reach for a break in the canopy formed ... avoidance syndrome or SAS. Now, the molecular details of SAS ... Institute for Biological Studies. To step out of ... for the synthesis of the plant growth hormone auxin that ...
... Cold Spring Harbor, NY In the neuromuscular disease ... caused by a single gene mutation leads to serious ... control. Now, in laboratory experiments, researchers at ... induced cells to replenish the protein by activating an ...
... born with silver spoons in their mouths. The same ... world, according to research done in part by the ... squirrels in Kluane, Yukon, revealed that advantageous silver spoon ... between birth and weaning could reflect later on each ...
Cached Biology News:A place in the sun 2A place in the sun 3Cold Spring Harbor Laboratory scientists devise potential approach to treat spinal muscular atrophy 2
... Activins are polypeptide hormones which belong ... superfamily. The TGF- superfamily is a ... which control many aspects of development, ... Other members incude TGF-s, bone morphogenetic ...
... Activins are polypeptide hormones which ... (TGF-) superfamily. The TGF- superfamily is ... factors which control many aspects of ... (1). Other members incude TGF-s, bone ...
... are polypeptide hormones which belong to ... The TGF- superfamily is a large ... control many aspects of development, reproductive ... members incude TGF-s, bone morphogenetic proteins, ...
... Sterile plating in just seconds , ... ethanol flaming, More uniform spreading and more ... dispenser bottle for spreading 100 plates or single-use ... easiest way to spread cells on multiple plates ...
Biology Products: