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23ème congrès européen sur l'Hypertension et la Protection Cardiovasculaire
Date:6/25/2013

233;té abordée dans l'étude SEVITENSION,[8] dont les premiers résultats ont été présentés lors d'une session de posters dans le cadre du congrès de l'ESH 2013.

L'étude SEVITENSION avait pour objectif de déterminer si l'association fixe olmésartan /amlodipine 40/10 mg pouvait réduire la pression artérielle centrale jusqu'à un niveau similaire à celui obtenu avec l'association du périndopril 8 mg et de l'amlodipine 10 mg, traitement utilisé dans l'étude CAFÉ. Les résultats montrent que non seulement cet objectif a été atteint, mais aussi que la réduction de la pression artérielle centrale était plus importante avec l'association fixe olmésartan /amlodipine 40/10 mg qu'avec l'association du périndopril 8 mg et de l'amlodipine 10 mg. Les autres mesures de la pression artérielle, brachiale conventionnelle ou en ambulatoire sur 24 heures, ont aussi confirmé la supériorité de l'association fixe olmésartan /amlodipine 40/10 mg. Par ailleurs, chez les trois quarts des patients (75,6%) traités avec l'association fixe olmésartan /amlodipine 40/10 mg, la pression artérielle était normalisée et donc inférieure au seuil recommandé par la Société Européenne d'Hypertension pour tous les patients hypertendus (PA<140/90 mmHg).[9] La proportion de patients ayant obtenu ce niveau de pression artérielle avec l'association du périndopril 8 mg et de l'amlodipine 10 mg était presque 20% plus faible (57,5%). "Depuis la publication de l'étude CAFÉ, la référence était l'association du périndopril 8 mg et de l'amlodipine 10 mg, c'est pourquoi nous avons comparé ce traitement de référence avec l'association fixe olm&
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