Navigation Links
2 for 1: Simultaneous size and electrochemical measurement of nanomaterials
Date:3/7/2012

Researchers at the National Institute of Standards and Technology (NIST) have done a mash-up of two very different experimental techniquesneutron scattering and electrochemical measurementsto enable them to observe structural changes in nanoparticles as they undergo an important type of chemical reaction. Their recently published technique* allows them to directly match up particle size, shape and agglomeration with the "redox" chemical properties of the particles. The measurements are important both for the design of nanoparticles for particular applications and for toxicology studies.

Nanoparticles present unique engineering challengesand opportunitiesbecause their extremely small size can give them physical properties quite unlike those they have in bulk quantities. The challenge for materials scientists is to determine just what those changes are and how they relate to particle size and structure.

The NIST team was interested in the oxidation-reductionredox properties of zinc oxide nanoparticles, which are used or being considered for a wide variety of applications ranging from sunscreens and antibacterial coatings to semiconductor and photoelectronic devices.

Redox reactions are one of the major divisions of chemical reactions, those that involve a transfer of electrons from one atom or molecule to another. Redox properties determine the path a chemical reaction will take. "They are the drivers of many biological processes," explains NIST materials researcher Vivek Prabhu. "There are many biochemical reactions that are well-defined oxidation-reduction reactions. There are tables of these. But there are no such tables that we know of on how nanoparticles can affect those reactions."

The NIST team knew they could monitor the size, shape and dispersion of nanoparticles in solution using SANSsmall-angle neutron scattering. The scattering patterns from a SANS instrument, says Prabhu, give you not only those details but structural information about the solution itself, the size distribution of the particles and whether they clump together, all in "real" time as the experiment progresses.

Redox properties, on the other hand, are measured in electrochemical cells that are essentially half of a battery. Voltage and the amount of current flowing through the primary electrode depend on the reaction redox potential and the concentration of the test material.

The problem, Prabhu explains, is that SANS measures things in bulk, in a volume of space, but, "An electrochemical experiment is a very local experimentit happens at an interface. What we needed was to maximize the interface." The answer, contributed by his partner, Vytas Reipa, is an exotic material called reticulated glassy carbon. "Like a very stiff household sponge or scouring pad made of pure carbon," Prabhu explains. The porous carbon electrode turned out to be an ideal terminallots of surface area to serve as a reaction interface; nearly transparent to neutrons, so it doesn't contribute much background noise; and best of all, it works well in water, enabling the study of nanoparticles in aqueous solutions, critical for biological reactions.

A big advantage of the "eSANS" technique, Prabhu says, is its generality. "You can apply our method to nearly any dispersed material that is of interest to redox chemistrypolymers, redox proteins, nucleic acidsat this nanoscale. Small polymer chains, for example. You can't really see them with electron microscopy, you can with neutrons."


'/>"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Related biology technology :

1. New technique allows simultaneous tracking of gene expression and movement
2. Cepheid Receives FDA Clearance for Xpert Flu, Delivering Simultaneous Detection and Differentiation of Flu A, Flu B, and 2009 H1N1 Strain
3. Using lasers to vaporize tissue at multiple points simultaneously
4. The Modern DeBakey VAD™ To Be Introduced For the First Time in the U.S. : HeartAssist 5™ Pediatric VAD Features Industry Exclusive Direct Blood Flow Measurement System
5. GEMS Introduces Ultrasonic Continuous Liquid Level Sensor for Challenging Fluid Measurement
6. Atherotech Receives Patent for ApoB Measurement
7. NISTs LIDAR may offer peerless precision in remote measurements
8. Nano measurement in the third dimension
9. deCODE Finds Genetic Factors Impacting Key Clinical Measurements of Heart Activity and Disease Risk
10. Computerized IVF Follicle Measurements are Faster and Give High Success Rates, Says Research from Chicago Fertility Doctors Richard Sherbahn and Todd Deutch
11. New measurement into biological polymer networks
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
2 for 1: Simultaneous size and electrochemical measurement of nanomaterials
(Date:12/2/2016)... 2, 2016 More than $4.3 million was raised ... ( DHMD ). The gala was held at the American ... City and honored Alan Alda and ... health and medicine and the public understanding of science. Since ... the event has raised $40 million for the Laboratory,s research ...
(Date:12/2/2016)... Amgen (NASDAQ: AMGN ) and Allergan ... of a Marketing Authorization Application (MAA) to the European Medicines ... ® (bevacizumab). The companies believe this submission is the ... "The submission of ABP 215 to the EMA is ... portfolio," said Sean E. Harper , M.D., executive vice ...
(Date:12/2/2016)... DUBLIN , Dec 2, 2016 ... new report "Nanobiotechnology Applications, Markets and Companies" to ... , ... of nanobiotechnology by the pharmaceutical and biotechnology industries is anticipated. ... - from formulations for optimal delivery to diagnostic applications in ...
(Date:12/2/2016)... ... December 01, 2016 , ... ... the value of DNA microarray comparative genomic hybridization (array CGH) for HER2 ... Cancer Symposium. Using molecular test results from tumors with previously documented positive, ...
Breaking Biology Technology:
(Date:11/17/2016)... announces that it has just released a new white paper authored by Zettar that ... speed data transfer storage solutions. Photo - http://photos.prnewswire.com/prnh/20161116/440463 ... ... ... Setting up a high performance computing or HPC system can be a ...
(Date:11/15/2016)... Nov 15, 2016 Research and Markets has ... to 2021" report to their offering. ... ... Billion by 2021 from USD 6.21 Billion in 2016, growing at ... Growth of the bioinformatics market is driven by the growing demand ...
(Date:6/27/2016)... Research and Markets has announced the addition of the ... The report forecasts the biometrics ... a CAGR of 12.28% during the period 2016-2020. ... with inputs from industry experts. The report covers the market landscape ... includes a discussion of the key vendors operating in this market. ...
Breaking Biology News(10 mins):