Navigation Links
$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research
Date:7/22/2014

es may go awry.

(iii) Develop cellular and animal models that faithfully mimic human disorders. In contrast to researchers studying cancer or diabetes, researchers studying psychiatric disorders have been unable to identify animal models that correctly capture important biological aspects of the disorders and correctly predict which therapies will be effective in humans. Now, with growing knowledge of the genes underlying psychiatric disorders, Broad researchers plan to create cellular models in the laboratory and animal models that more faithfully match both the genetic variation and the biochemical processes seen in human patients. They plan to pioneer cutting-edge techniques such as genome editing, which allows them to precisely introduce any mutations they choose.

(iv) Develop chemicals to modulate biological pathways to serve as drug leads. The researchers plan to build on the existing therapeutic efforts within the Stanley Center and draw on the Broad's Therapeutics Platform – a technological powerhouse with the capacity to create and screen hundreds of thousands of compounds – to identify molecules that can powerfully and precisely influence specific biological pathways relevant to psychiatric disorders. They then plan to comprehensively investigate those chemicals' effects to determine which of them might serve as promising leads for drugs that could be safely and effectively used in humans.

"We're still at the beginning of the curve of translating the emerging genetics into actionable biology, but it's happening much faster than I thought it would," said Scolnick. "I'd be bold enough to say that in five years, all the drug companies that got out of psychiatric research will be getting back in. The coming decades of psychiatric research will yield new science and a needed parallel effort to increase resources for services that can help patients and their families."

About the Stanley Center for Psychiatr
'/>"/>

SOURCE Broad Institute
Copyright©2014 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related biology technology :

1. Edico Genome Raises $10 Million in Series A Financing to Commercialize DRAGEN Chip to Overcome Sequencing Data Analysis Bottleneck
2. Avelas Biosciences Closes $6.85 Million in Series B Financing to Advance Real-Time Cancer Visualization Technology to Clinical Proof-of-Concept
3. Columbia Engineering wins $3 million ARPA-E grant to raise efficiency, lower cost of power grid
4. Mice Model Market worth $1,819.9 Million by 2018
5. Epizyme and Celgene Advance EPZ-5676 DOT1L Inhibitor Clinical Program to Benefit Cancer Patients with Acute Leukemias, Achieving $25 Million Clinical Proof of Concept Milestone
6. PCCI Collaborates With UTSW On Top National Research Grants Totaling Over $30 Million
7. BioLife Solutions Preliminary 2013 Revenue Grows to $9 Million
8. Star Scientific, Inc. Arranges a $15 Million Credit Facility
9. Lineagen Announces $3.5 Million Series C Round and Close of Series B Financing
10. Curoverse Raises $1.5 Million to Build Open Source Platform for Genomic and Biomedical Big Data
11. CNTS Awarded $40 Million Contract Supporting U.S. Military Through Global Public Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... , Nov. 18, 2014  Great Basin Scientific, Inc. ... announced that the management will host a conference call and ... development programs on Thursday, Nov. 20, at 4:30 pm EST ... have made since the Company,s recent IPO and would like ... Basin,s management," said Ryan Ashton , President and Chief ...
(Date:11/17/2014)... The new METTLER TOLEDO White ... the challenges of becoming the first calibration laboratory ... calibration weights in the microgram range. National Metrology ... any scientists involved in nanotechnology applications will benefit ... and calibration of weights in the range of ...
(Date:11/16/2014)... 2014 The “Fluid Management & ... visualization systems market with an analysis and forecast ... irrigation, dialyzes, fluid warming and waste management. Along ... fluid visualization systems by applications and regions are ... was valued at $19,285.5 million in 2013 and ...
(Date:11/15/2014)... Collaborative Consulting, a privately held, employee-based ... of the Boston Globe’s “Top Places to Work 2014”. ... Massachusetts to receive the honor. , The Boston Globe’s ... of their most valuable resource: the people who work ... are based on an array of criteria, including the ...
Breaking Biology Technology:Great Basin Scientific Announces Conference Call to Provide Update on Corporate Progress 2New White Paper on Microgram Weights Describes How to Achieve Traceable Measurement Down to 0.05 Milligrams 2Fluid Visualization Systems Market poised to reach $25,908.4 Million by 2018 - New Research Report by MarketsandMarkets 2Fluid Visualization Systems Market poised to reach $25,908.4 Million by 2018 - New Research Report by MarketsandMarkets 3Fluid Visualization Systems Market poised to reach $25,908.4 Million by 2018 - New Research Report by MarketsandMarkets 4Collaborative Consulting Honored with Boston Globe Top Places to Work 2014 2
... (Amex: IMA ) today announced that it has ... Australian company traded on,the Australian Securities Exchange, under which ... issued shares in Panbio for AUD 0.65 cash,per share. ... of,Panbio at approximately AUD 41 million, or approximately USD ...
... ExL Pharma, Cision and the PRSA have,joined ... biotech,public relations executives the first Pharmaceutical Public Relations,Symposium ... This,one-day event will cover the key issues and ... is under ongoing political and media scrutiny,most notably ...
... USC,s Increased Commitment to Research Advancements in Health ... Robust Life Science Industry in Los Angeles, LOS ... University of Southern California,s strengthened,commitment to advancing breakthrough research ... today the opening of an office,in the new Harlyne ...
Cached Biology Technology:Inverness Medical Innovations Agrees to Acquire Panbio Ltd. 2Leading Pharmaceutical Communication Executives Gather for the 1st Annual Pharmaceutical Public Relations Symposium 2The USC Stevens Institute for Innovation Opens Shop on US Health Sciences Campus 2The USC Stevens Institute for Innovation Opens Shop on US Health Sciences Campus 3The USC Stevens Institute for Innovation Opens Shop on US Health Sciences Campus 4
(Date:11/6/2014)... when that predator runs so fast that it essentially blinds ... the fastest creature on Earth. Some of these half-inch-long beetles ... miles per hour). The fastest human can do about five ... beetle, a person would have to hit 480 miles per ... peak speeds, everything becomes a blur. They can,t gather enough ...
(Date:11/5/2014)... Santamaria, associate professor of biology in the UTSA ... in the nation selected to receive a two-year ... for Exploratory Research (EAGER). The funding supports President ... researchers to create new technology that will demystify ... complex behaviors in neuroscience are broken into the ...
(Date:11/5/2014)... Janeiro, Brazil -Individuals show great diversity in their ability ... and females greatly differ in their perceptual evaluation of ... smell tests. , Sex differences in olfactory ... and may be connected to one,s perception of smell, ... Thus, women,s olfactory superiority has been suggested to be ...
Breaking Biology News(10 mins):The tiger beetle: Too fast to see 2UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3The female nose always knows: Do women have more olfactory neurons? 2
... green tea dramatically boosted production of a group ... levels of these beneficial proteins, according to researchers ... published in the August issue of Cancer Epidemiology, ... Association for Cancer Research, suggest that a green ...
... has shattered a long-held belief that no direct pathway ... cell nucleus. (The cell is the smallest metabolically functional ... material outside of a cell can migrate into a ... phagocytosis, in which extracellular material is captured by a ...
... Alcohol and smoking can be harmful, if not deadly. ... environmental cues, genomic factors also play an important role. The ... complex interactions with the environment. Adoption and twin studies have ... be inherited. Such studies have provided evidence that ones sex ...
Cached Biology News:Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless 2New, more direct pathways from outside the cell-to-cell nuclei discovered 2New, more direct pathways from outside the cell-to-cell nuclei discovered 3Does the desire to consume alcohol and tobacco come from our genetic makeup? 2Does the desire to consume alcohol and tobacco come from our genetic makeup? 3
...
... high-density serum biomarker chip to profile the ... antibody chip containing 120 human cancer serum ... biomarker discovery scientists to study panels of ... therapy and the likelihood of recurrence of ...
... Ventilates and removes chemical fumes, ... exhaust. Bonded charcoal filters remove ... ensure safe exhaust flow speed ... access opening. Includes air speed ...
Sigmas E-TOXATE (Limulus Amebocyte Lysate) test kits are intended for the detection and semiquantitation,of endotoxins for research purposes....
Biology Products: