Navigation Links
$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research
Date:7/22/2014

es may go awry.

(iii) Develop cellular and animal models that faithfully mimic human disorders. In contrast to researchers studying cancer or diabetes, researchers studying psychiatric disorders have been unable to identify animal models that correctly capture important biological aspects of the disorders and correctly predict which therapies will be effective in humans. Now, with growing knowledge of the genes underlying psychiatric disorders, Broad researchers plan to create cellular models in the laboratory and animal models that more faithfully match both the genetic variation and the biochemical processes seen in human patients. They plan to pioneer cutting-edge techniques such as genome editing, which allows them to precisely introduce any mutations they choose.

(iv) Develop chemicals to modulate biological pathways to serve as drug leads. The researchers plan to build on the existing therapeutic efforts within the Stanley Center and draw on the Broad's Therapeutics Platform – a technological powerhouse with the capacity to create and screen hundreds of thousands of compounds – to identify molecules that can powerfully and precisely influence specific biological pathways relevant to psychiatric disorders. They then plan to comprehensively investigate those chemicals' effects to determine which of them might serve as promising leads for drugs that could be safely and effectively used in humans.

"We're still at the beginning of the curve of translating the emerging genetics into actionable biology, but it's happening much faster than I thought it would," said Scolnick. "I'd be bold enough to say that in five years, all the drug companies that got out of psychiatric research will be getting back in. The coming decades of psychiatric research will yield new science and a needed parallel effort to increase resources for services that can help patients and their families."

About the Stanley Center for Psychiatr
'/>"/>

SOURCE Broad Institute
Copyright©2014 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related biology technology :

1. Edico Genome Raises $10 Million in Series A Financing to Commercialize DRAGEN Chip to Overcome Sequencing Data Analysis Bottleneck
2. Avelas Biosciences Closes $6.85 Million in Series B Financing to Advance Real-Time Cancer Visualization Technology to Clinical Proof-of-Concept
3. Columbia Engineering wins $3 million ARPA-E grant to raise efficiency, lower cost of power grid
4. Mice Model Market worth $1,819.9 Million by 2018
5. Epizyme and Celgene Advance EPZ-5676 DOT1L Inhibitor Clinical Program to Benefit Cancer Patients with Acute Leukemias, Achieving $25 Million Clinical Proof of Concept Milestone
6. PCCI Collaborates With UTSW On Top National Research Grants Totaling Over $30 Million
7. BioLife Solutions Preliminary 2013 Revenue Grows to $9 Million
8. Star Scientific, Inc. Arranges a $15 Million Credit Facility
9. Lineagen Announces $3.5 Million Series C Round and Close of Series B Financing
10. Curoverse Raises $1.5 Million to Build Open Source Platform for Genomic and Biomedical Big Data
11. CNTS Awarded $40 Million Contract Supporting U.S. Military Through Global Public Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 2014 Involution Studios , a ... a new infographic, Understanding Ebola . The ... designed, easy to follow informative tool for anyone wanting ... symptoms and prevention. , "As the news has spread ... Ebola outbreak represents not only a healthcare crisis with ...
(Date:10/22/2014)... According to new market research report ... Integration, Deployment & Support), by Service Model (SaaS, ... Others (Hybrid & Community)) - Global Forecast to ... Cloud Professional Services Market into various sub-segments with ... also identifies the drivers and restraints for this ...
(Date:10/22/2014)... and HONG KONG , ... rare disease therapeutics enterprise, announced today that rare disease ... company as vice president, research. Dr. McKew brings more ... key leadership positions at the National Institutes of Health, ... acquisition by Wyeth). Dr. McKew will lead aTyr,s efforts to ...
(Date:10/20/2014)... 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") ... orders to $5.8 million and provides a good start to Q4.  ... North America and one in the Middle ... at record levels," said Peter Bruijns , President & CEO. ... of Q3 than they have been for any complete year since ...
Breaking Biology Technology:Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3
... BC, March 20 /PRNewswire-FirstCall/ - Chromos Molecular,Systems Inc. ... a secured, convertible debenture agreement to borrow $400,000. ... to fund expenses associated with the,preparation of delinquent ... remaining assets of the Company. The principal and,interest, ...
... January 7,2008, Signalife received a deficiency letter from ... advised that Signalife would need to,comply with the ... under AMEX Rules 1003(a)(iii). This notification was,triggered by ... than,$50 million, which previously exempted Signalife from meeting ...
... as Interim President, HOUSTON, March 20 Nova ... marketer of ASTM quality biodiesel, announced,today that it has ... its Interim President. Mr. Zeidman has been a Nova ... Managing Director of the law firm,Greenberg Traurig, LLP since ...
Cached Biology Technology:Chromos enters into loan and lending arrangements 2AMEX Notifies Signalife That It Has Accepted Signalife's Plan of Compliance 2Nova Biosource Fuels Expands Senior Executive Team 2Nova Biosource Fuels Expands Senior Executive Team 3
(Date:10/15/2014)... to an unexpected extent. The outbreak does not follow ... shows a new disease dynamic in regions, where it ... German National Academy of Sciences Leopoldina, acatech – the ... of the German Academies of Sciences and Humanities have ... In the statement the academies call for the following ...
(Date:10/15/2014)... 15, 2014   Neurotechnology , a provider ... availability of the VeriLook Surveillance 3.0 software ... real-time biometric face identification using live video streams ... The new version not only identifies faces in ... objects while they are moving through the video ...
(Date:10/14/2014)... sequenced the house fly genome for the first time, ... an insect that thrives in pathogen-rich dung piles and ... the journal Genome Biology , will increase understanding ... flies quickly adapt to resist insecticides, which could lead ... domestica) carry and transmit more than 100 human and ...
Breaking Biology News(10 mins):Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3House fly genome reveals expanded immune system 2
... Solutions, a global life sciences technology solutions company ... to announce the latest release of ENLIGHTEN ... ENLIGHTEN system, which provides a proven, highly ... clinical trial management system (CTMS), has effectively supported ...
... University of Tennessee, Knoxville, researchers have found ... an estrogen-like compound in the environment which could ... adversely affect fish, plants and human health. Previously, ... these impacts. Theodore Henry, an adjunct ...
... is pleased to announce the recipients of the 2010 ... Advancement of Biotherapy. The 6 award winners were presented ... in Los Angeles; they are: David Armstrong, MD, DPM, ... MD, MPH; Kosta Mumcuoglu, PhD; and Aletha Tippett, MD, ...
Cached Biology News:MedNet Solutions Announces Significant Enhancements to ENLIGHTEN, Its Flagship EDC / eClinical Solution 2UT researchers link algae to harmful estrogen-like compound in water 2BTER Foundation announces winners of the William S. Baer Award 2BTER Foundation announces winners of the William S. Baer Award 3
... Amplification Kit, 100 reactions. Prepare circular ... 4-6 h.Generate microgram quantities of template ... material.Use amplified DNA directly for cycle ... or M13 liquid cultures, colonies, plaques, ...
... Microplate Rack inserts fit ... Rack, and allow you to ... capacity, shake deepwell format plates ... many plates from the shaker ...
BD FastImmune EDTA Solution. Applications: Flow Cytometry Storage Temperature: Refrigerate(2 to 8C)...
Spaced cover glasses to promote effective hybridization...
Biology Products: