Navigation Links
Ubiquitin Fraction I Extract from GeneTex

ProductsUbiquitin Fraction I Extract from GeneTex
Company GeneTex
Item Ubiquitin Fraction I Extract
Price $400.00
Description Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (~31), barrel-shaped molecular machine with an apparent molecular weight of ~2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelmans syndrome, and Liddle syndrome. GTX80876 is the protein fraction of HeLa cell extract that does not bind to anion exchange resin. GTX80876 contains ubiquitin, ubiquitin conjugating enzymes (E2s), and ubiquitin ligases (E3s). GTX80876 is ideal for demonstrating if FI enzymes are critical for degradation of in vitro substrates as well as in vitro conjugation activity.

  • Type: Proteins and peptides
  • Form: 8 mg/ml protein from HeLa cells in 25 mM HEPES, pH 7.6.
Info GeneTexGeneTex
14785 Omicron Dr. Suite101
San Antonio, TX 78245
Customer Service: (877) 436-3839
Fax Number: (210) 677-8843
Web Site: http://www.genetex.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Ubiquitin/Proteasome Fraction II Extract from GeneTex
2. Ubiquitin Fraction I from ABR-Affinity BioReagents
3. Mouse Anti-Ubiquitin, Multi Monoclonal Antibody, Unconjugated, Clone FK2 from Assay Designs/Stressgen Bioreagents
4. Ubiquitin Related I Sampler Kit from BD Biosciences Pharmingen
5. Rabbit Anti-Human Ubiquitin-conjugating enzyme E2N Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.
6. ProteomeLab PF 2D Protein Fractionation System from Beckman Coulter
7. UBC Fractions Extract from GeneTex
8. 26S Proteasome Fraction Extract from GeneTex
9. 26S Proteasome Fraction Extract from GeneTex
10. FractionPREP Cell Fractionation Kit from BioVision
11. cDNA Size Fractionation Columns from Invitrogen
Purified Mouse anti-Hu Actopaxin (pS8) Storage Temperature: Refrigerate(2 to 8C)...
... FastPlax Antibody is used to detect the ... surface of infected cells as early as ... of the FastPlax Titer Kit, which allows ... hours. The FastPlax Antibody can ...
b-Catenin (pSer675), phospho-specific...
Naked1 Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Biology Products:
(Date:6/3/2016)... , June 3, 2016 ... Management) von Nepal ... und Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, ... führend in der Produktion und Implementierung von ... der Ausschreibung im Januar teilgenommen, aber Decatur ...
(Date:6/2/2016)... June 2, 2016   The Weather Company , an ... Ads, an industry-first capability in which consumers will be able ... to ask questions via voice or text and receive relevant ... Marketers have long sought an advertising solution ... can be personal, relevant and valuable; and can scale across ...
(Date:6/1/2016)... -- Favorable Government Initiatives Coupled With Implementation ... to Boost Global Biometrics System Market Through 2021  ... " Global Biometrics Market By Type, By End ... - 2021", the global biometrics market is projected to ... growing security concerns across various end use sectors such ...
Breaking Biology News(10 mins):
(Date:12/5/2016)... ... December 05, 2016 , ... The ... the nation’s premier cannabis technology and application experts, Chip Baker. Chip Baker formerly ... Colorado. Over the past 30 years, Chip Baker other industry veterans have made ...
(Date:12/5/2016)... According to the new ... (Consumable, Instruments, Automated Cell Expansion System), Cells Types ... Research, Cancer, and Cell-Based Research), End-users (Biopharmaceutical and ... Revenue, Trends, Growth, Share, Size and Forecast to ... cell expansion market is expected to reach USD ...
(Date:12/5/2016)... Dec. 5, 2016 /PRNewswire/ - Resverlogix Corp. ("Resverlogix" ... independent Data and Safety Monitoring Board (DSMB) for ... cardiovascular disease (CVD) patients has completed a second ... should continue as planned without any modifications. The ... no safety or efficacy concerns were identified. The ...
(Date:12/5/2016)... 2016  Eisai Inc. announced today final results ... rufinamide, which were presented at the 2016 Annual ... from December 2-6 in Houston, Texas ... and cognitive data showed that patients who received ... tolerability profiles, cognitive development and behavior, compared to ...
Breaking Biology Technology: