Navigation Links
Rabbit Anti-Aph-1aL, S Loop (92-115) Polyclonal Antibody, Unconjugated from Covance Research Products, Inc

ProductsRabbit Anti-Aph-1aL, S Loop (92-115) Polyclonal Antibody, Unconjugated from Covance Research Products, Inc
Company Covance Research Products, Inc
Item Rabbit Anti-Aph-1aL, S Loop (92-115) Polyclonal Antibody, Unconjugated
Price $353.00
Description Polyclonal Antibody against Aph-1a (Aph-1aL,S Loop 92-115), O2F1

Affinity Purified Antibody

The gamma secretase is a multiprotein complex consisting of presenilin, nicastrin, Aph-1 and Pen-2; all four proteins are necessary for full proteolytic activity. The gamma secretase complex catalyzes cleavage of a number of integral membrane proteins including Amyloid precursor protein, Notch, Erb4 and E-cadherin. While Aph-1 stabilizes the presenilin holoprotein within the gamma secretase complex, Pen-2 is required for endoproteolysis of presenilin and activation of the gamma secretase.
The Aph-1 homologue on human chromosome 1 is termed Aph-1a and on human chromosome 15 is referred to as Aph-1b. The antibody Aph-1aL/SLoop (O2F1) was raised against the human Aph-1aL/S Loop region 92-115 and recognizes the sequence CKLLKKADEGLASLSEDGRSPISIR.
Covance also offers an antibody O2C2 (PRB-550P) which recognizes the C terminal sequence 245-265 of Aph-1aL.

This antibody is effective in immunoblotting and immunostaining.

Info Covance Research Products, IncCovance Research Products, Inc
P.O. Box 7200
Denver, Pennsylvania 17517

Customer Service:
800-345-4114 (Toll Free)
717-336-4921

Fax Number:
717-336-5344

Web Site: http://www.crpinc.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Rabbit Anti-Human Vitamin K-dependent Protein S (PROS1) Polyclonal Antibody, Unconjugated from Lifespan Biosciences
2. Rabbit Anti-Human Sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7 (SIRT7) Polyclonal Antibody, Unconjugated from Lifespan Biosciences
3. Rabbit Anti-Esa1 Polyclonal Antibody, Unconjugated from Abcam
4. Rabbit Anti-Human Rad51 Polyclonal Antibody, Unconjugated from Abcam
5. Human CALCA EIA (Enzyme immunoassay) Kit, Host: Rabbit ; Extraction-free from BACHEM
6. MaxArray Tissue Array (Animal - Rabbit) from Invitrogen
7. Rabbit Anti-GST Polyclonal Antibody, Unconjugated from Novus Biologicals
8. Rabbit Anti-Shigella Polyclonal Antibody, Unconjugated from GeneTex
9. Vaginal Keratinocyte Progenitors, Rabbit from CHEMICON
10. Dermal Fibroblasts, Rabbit from CHEMICON
11. Normal Rabbit Tissues from CHEMICON
Spectrolyse (pL) PAI kit is a two-stage indirect enzymatic assay for the quantitative determination of Plasminogen Activator Inhibitor (PAI-1) activity in plasma. Sample Type: plasma...
NAK/TBK1 (CT) Affinity Purified Polyclonal Antibody...
... human cardiac troponin subunit T, a 31kDa protein ... contraction of cardiac muscle. It reacts with subunit ... It also cross-reacts with human skeletal troponin T ... Highly purified human cardiac troponin T ...
... is pleased to offer the ATTO-TAG ... detection of primary amines. Developed by ... the ATTO-TAG reagents are similar to ... (NDA) and anthracene-2,3-dicarboxaldehyde, all of which ...
Biology Products:
(Date:7/24/2014)... This news release is available in German . ... has evolved to recognize and respond to threats to ... disease. A detailed understanding of the mechanism underlying immunologic ... of research have converged to support the hypothesis that ... of immune cells with stem-cell-like potential. Until now, there ...
(Date:7/24/2014)... 2014 NXT-ID, Inc., (NXTD: OTCQB) a biometric authentication company ... smart wallet, Wocket™, was recently the topic of  an interview ... Gino Pereira , CEO of NXT-ID, on July ... Mr. Gino Pereira explains how the ... cards and walks host Anita Finley through ...
(Date:7/24/2014)... Odds are, theres a virus living inside your gut ... new study led by researchers at San Diego State ... population is host to a newly described virus, named ... of gut bacteria, Bacteroidetes . This phylum of ... and other gut-related diseases. The research appears today in ...
Breaking Biology News(10 mins):Experiments prove 'stemness' of individual immune memory cells 2Experiments prove 'stemness' of individual immune memory cells 3Boomer Times Gets to Know NXT-ID's Next Generation Wocket Smart Wallet; Practical, Secure and Easy to Use 2Boomer Times Gets to Know NXT-ID's Next Generation Wocket Smart Wallet; Practical, Secure and Easy to Use 3Boomer Times Gets to Know NXT-ID's Next Generation Wocket Smart Wallet; Practical, Secure and Easy to Use 4Newly discovered gut virus lives in half the world's population 2Newly discovered gut virus lives in half the world's population 3
... has destroyed 17 percent of the native vegetation in ... new study published by Conservation International sounds an alarm ... Continued deforestation at the current rate would cause all ... years, according to CI researchers in Brazil. , Overall, ...
... It's one of those unavoidable facts of life -- ... internal temperatures cause only temporary discomfort, but in some ... , These convulsions are "scary and very upsetting to ... chair of Neurology. They've also been something of an ...
... shows that robot assisted knee surgery is significantly ... of surgeons tested whether Acrobot, a robotic assistant, ... knee replacement. Acrobot works by helping the surgeon ... the existing bones. , The surgeons looked at ...
Cached Biology News:Report shows deforestation threatens Brazil's Pantanal 2Molecular mechanism may explain how fevers spark seizures 2Molecular mechanism may explain how fevers spark seizures 3Robot assisted surgery more accurate than conventional surgery 2
(Date:7/24/2014)... (PRWEB) July 24, 2014 2014 ... Sulphate Industry” is a professional and in-depth research ... introduces Potassium Sulphate basic information, including its ... industry overview. This research covers the international market ... global industry analysis covering macroeconomic environment & economic ...
(Date:7/24/2014)... 2014  Neogen Corporation (Nasdaq: NEOG ) ... potential revenue from new rodenticide research are premature. In ... on July 22, 2014, Neogen,s CEO commented about several ... "It was my intent Tuesday at our ... a new type of rodenticide, but certainly not to ...
(Date:7/24/2014)... 24, 2014 WIRB-Copernicus Group ® ... ethical review services for clinical research, announced today ... division of Richmond, VA -based ... and biosecurity consulting firm in the ... biosafety division – WCG Biosafety™ – will be ...
(Date:7/24/2014)... 1000 balances – 4 steps – One ... needs and expertly narrows down the mass of product ... even terminals. , First, select the working environment, ... readability instead) and define the accuracy – it’s really ... down the list to models that fit best with ...
Breaking Biology Technology:Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 2Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 3Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 4Neogen comments on SenesTech 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3