Navigation Links
Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.

ProductsPorcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.
Company Diagnostic Systems Laboratories, Inc.
Item Porcine Leptin ELISA Kit
Description Leptin is a proteohormone with a molecular weight of 16 kDa. Leptin is a protein encoded by the ob gene and produced by adipocytes [1,2]. Leptin is thought to play a key role in the regulation of body weight [1-3]. In the human, leptin levels are elevated with increasing adiposity in both men and women [4]. A relationship between serum leptin levels and several measures of adiposity (e.g. body mass index (BMI) or percent body fat) demonstrates that leptin levels are elevated even in obese patients. The failure of these elevated leptin levels to alter the obese state of these individuals may be related to a leptin resistance and an inability of leptin to enter the cerebral spinal fluid to reach sites in the hypothalamus to regulate appetite. Involvement of a leptin receptor or carrier protein in this kind of regulation has been suggested. Serum leptin levels follow a circadian rhythm, which seems to be regulated predominantly by postprandial increases in insulin and the normal circadian rhythm of cortisol. Although these hormones do not work in the short term, the long-term administration both in vivo and in vitro indicates that these two hormones may be some of the major regulators of leptin production by adipose tissue. Without an understanding of leptin regulation and how to circumvent leptin resistance, the use of leptin to treat the obese individual remains a question for future research. Leptin levels have been shown to change under certain endocrine conditions. For example when leptin levels are expressed per body adiposity, females have higher leptin levels than do males. This may be related to the distribution of adipose tissue where omental fat vs. subcutaneous fat, which differs between gender, may have different leptin production rates. The nature of circulating leptin has not been fully explored but the suggestion that it is bound to a circulating protein has been presented. Whether this is a separate protein or represents a circulating form of the leptin receptor remains to be investigated but this may be an important form of regulation to explain rapid changes in serum leptin levels that may occur. Some examples of rapid changes in leptin levels would be starvation and forced feeding where changes within 24 to 48 hours are readily observed in serum leptin concentrations. Similarly, there are rapid declines postpartum suggesting that something other than the amount of adipose tissue may regulate circulating levels of leptin. Many areas of leptin physiology remain to be investigated. Leptins role in metabolism, insulin sensitivity, as a potential therapeutic modality for weight loss as well as its involvement in endocrine function are active areas of research. While the future for leptin as a therapeutic agent is not clear, its involvement in many areas of physiology undoubtedly makes this a new hormone which will require extensive study in the next few years to understand its physiology.
Info Diagnostic Systems Laboratories, Inc.Diagnostic Systems Laboratories, Inc.
Diagnostic Systems Laboratories, Inc.
445 Medical Center Blvd
Webster Texas 77598
Customer Service: (800) 231-7970
Fax Number: (281) 338-1895
Web Site:
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Porcine Galanin , 125I Conjugated/Tagged from PerkinElmer
2. Human, Porcine Endothelin-1 , 125I Conjugated/Tagged from PerkinElmer
3. Human, Porcine Endothelin-1 , 125I Conjugated/Tagged from PerkinElmer
4. Porcine Galanin , 125I Conjugated/Tagged from PerkinElmer
5. Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer
6. Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer
7. Porcine Angiotensin Converting Enzyme from BIOPUR
8. Mouse Anti-Porcine Pyruvate Dehydrogenase (PDH), complex Immunocapture Kit Monoclonal Antibody, Protein G-Agarose Conjugated, Clone 15D3G9C11 from MitoScience LLC
9. Rabbit Anti-Porcine Vitronectin Antibody, Unconjugated from Cosmo Bio Co., Ltd.
10. Porcine Galanin , 3-[125I]iodotyrosyl26 Conjugated/Tagged from GE Healthcare, formerly Amersham Biosciences
11. Porcine Galanin , 3-[125I]iodotyrosyl26 Conjugated/Tagged from GE Healthcare, formerly Amersham Biosciences
(Date:6/3/2016)... June 3, 2016 ... Nepal hat ein ... hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und ... der Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche ... im Januar teilgenommen, aber Decatur wurde als ...
(Date:6/2/2016)... The Weather Company , an IBM Business (NYSE: IBM ... which consumers will be able to interact with IBM Watson ... or text and receive relevant information about the product or ... long sought an advertising solution that can create a one-to-one ... valuable; and can scale across millions of interactions and touchpoints. ...
(Date:6/1/2016)... June 1, 2016 Favorable Government ... Administration and Criminal Identification to Boost Global Biometrics System ... released TechSci Research report, " Global Biometrics Market ... Forecast and Opportunities, 2011 - 2021", the global biometrics ... 2021, on account of growing security concerns across various ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , ... June 23, 2016 , ... ... pleased to announce the launch of their brand, UP4™ Probiotics, into Target stores ... 35 years, is proud to add Target to its list of well-respected retailers. ...
(Date:6/23/2016)... -- Houston Methodist Willowbrook Hospital has signed a ... serve as their official health care provider. As ... provide sponsorship support, athletic training services, and most ... athletes and families. "We are excited ... to bring Houston Methodist quality services and programs ...
(Date:6/23/2016)... FRANCISCO , June 23, 2016   EpiBiome ... has secured $1 million in debt financing from Silicon ... ramp up automation and to advance its drug development ... its new facility. "SVB has been an ... beyond the services a traditional bank would provide," said ...
(Date:6/23/2016)... 2016 Apellis Pharmaceuticals, Inc. today announced ... of its complement C3 inhibitor, APL-2. The trials ... dose studies designed to assess the safety, tolerability, ... in healthy adult volunteers. Forty subjects ... single dose (ranging from 45 to 1,440mg) or ...
Breaking Biology Technology: