Navigation Links
Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.

ProductsPorcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.
Company Diagnostic Systems Laboratories, Inc.
Item Porcine Leptin ELISA Kit
Description Leptin is a proteohormone with a molecular weight of 16 kDa. Leptin is a protein encoded by the ob gene and produced by adipocytes [1,2]. Leptin is thought to play a key role in the regulation of body weight [1-3]. In the human, leptin levels are elevated with increasing adiposity in both men and women [4]. A relationship between serum leptin levels and several measures of adiposity (e.g. body mass index (BMI) or percent body fat) demonstrates that leptin levels are elevated even in obese patients. The failure of these elevated leptin levels to alter the obese state of these individuals may be related to a leptin resistance and an inability of leptin to enter the cerebral spinal fluid to reach sites in the hypothalamus to regulate appetite. Involvement of a leptin receptor or carrier protein in this kind of regulation has been suggested. Serum leptin levels follow a circadian rhythm, which seems to be regulated predominantly by postprandial increases in insulin and the normal circadian rhythm of cortisol. Although these hormones do not work in the short term, the long-term administration both in vivo and in vitro indicates that these two hormones may be some of the major regulators of leptin production by adipose tissue. Without an understanding of leptin regulation and how to circumvent leptin resistance, the use of leptin to treat the obese individual remains a question for future research. Leptin levels have been shown to change under certain endocrine conditions. For example when leptin levels are expressed per body adiposity, females have higher leptin levels than do males. This may be related to the distribution of adipose tissue where omental fat vs. subcutaneous fat, which differs between gender, may have different leptin production rates. The nature of circulating leptin has not been fully explored but the suggestion that it is bound to a circulating protein has been presented. Whether this is a separate protein or represents a circulating form of the leptin receptor remains to be investigated but this may be an important form of regulation to explain rapid changes in serum leptin levels that may occur. Some examples of rapid changes in leptin levels would be starvation and forced feeding where changes within 24 to 48 hours are readily observed in serum leptin concentrations. Similarly, there are rapid declines postpartum suggesting that something other than the amount of adipose tissue may regulate circulating levels of leptin. Many areas of leptin physiology remain to be investigated. Leptins role in metabolism, insulin sensitivity, as a potential therapeutic modality for weight loss as well as its involvement in endocrine function are active areas of research. While the future for leptin as a therapeutic agent is not clear, its involvement in many areas of physiology undoubtedly makes this a new hormone which will require extensive study in the next few years to understand its physiology.
Info Diagnostic Systems Laboratories, Inc.Diagnostic Systems Laboratories, Inc.
Diagnostic Systems Laboratories, Inc.
445 Medical Center Blvd
Webster Texas 77598
Customer Service: (800) 231-7970
Fax Number: (281) 338-1895
Web Site:
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Porcine Galanin , 125I Conjugated/Tagged from PerkinElmer
2. Human, Porcine Endothelin-1 , 125I Conjugated/Tagged from PerkinElmer
3. Human, Porcine Endothelin-1 , 125I Conjugated/Tagged from PerkinElmer
4. Porcine Galanin , 125I Conjugated/Tagged from PerkinElmer
5. Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer
6. Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer
7. Porcine Angiotensin Converting Enzyme from BIOPUR
8. Mouse Anti-Porcine Pyruvate Dehydrogenase (PDH), complex Immunocapture Kit Monoclonal Antibody, Protein G-Agarose Conjugated, Clone 15D3G9C11 from MitoScience LLC
9. Rabbit Anti-Porcine Vitronectin Antibody, Unconjugated from Cosmo Bio Co., Ltd.
10. Porcine Galanin , 3-[125I]iodotyrosyl26 Conjugated/Tagged from GE Healthcare, formerly Amersham Biosciences
11. Porcine Galanin , 3-[125I]iodotyrosyl26 Conjugated/Tagged from GE Healthcare, formerly Amersham Biosciences
... sports 16-independent channels for automated gigaseal patch ... screening against voltage-gated ion channels, such as ... channels. The four pipette heads afford ... ion channel drug discovery. The glass-coated ...
... can operate as a Voltage Clamp, as ... Clamp in electrophysiology research applications. Performance in ... analog equipment. This amazing instrument is made ... of Digital Signal Processing (DSP) integrated circuit chips. ...
... able to handle larger sample volumes, automate infusions, ... interface with telemetry systems. The AccuSampler LA ... pigs, and primates. The system may be ... computer can be located outside the animal room ...
... Peptide Display Cloning System facilitates the display ... of bacteriophage M13 as coat protein fusions, ... peptide and its encoding DNA sequence. Peptide ... then be selected by the straightforward method ...
Biology Products:
(Date:8/15/2017)... ivWatch LLC , a medical device company focused on improving the ... its ISO 13485 Certification, the global standard for medical device quality ... ... device for the early detection of IV infiltrations. ... "This is an important milestone for ivWatch, as it validates ...
(Date:5/23/2017)... -- Hunova, the first robotic gym for the rehabilitation and functional motor sense ... Genoa, Italy . The first 30 robots will be available ... USA . The technology was developed and patented at the IIT ... Movendo Technology thanks to a 10 million euro investment from entrepreneur Sergio ... ...
(Date:4/19/2017)... ALBANY, New York , April 19, 2017 /PRNewswire/ ... highly competitive, as its vendor landscape is marked by ... in the market is however held by five major ... and Safran. Together these companies accounted for nearly 61% ... majority of the leading companies in the global military ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... Angeles, CA (PRWEB) , ... ... ... Inc., a development-stage cancer-focused pharmaceutical company advancing targeted antibody-drug conjugate (ADC) therapeutics, ... uses of targeted HPLN (Hybrid Polymerized Liposomal Nanoparticle), a technology developed in ...
(Date:10/10/2017)... Oct. 10, 2017 SomaGenics announced the receipt ... to develop RealSeq®-SC (Single Cell), expected to be the ... RNAs (including microRNAs) from single cells using NGS methods. ... need to accelerate development of approaches to analyze the ... "New techniques for measuring levels of mRNAs in ...
(Date:10/9/2017)... ... 2017 , ... The award-winning American Farmer television series will feature 3 Bar ... Tuesdays at 8:30aET on RFD-TV. , With global population estimates nearing ten billion ... continue to feed a growing nation. At the same time, many of our valuable ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... for microscopy and surface analysis, Nanoscience Instruments is now expanding into Analytical ... broad range of contract analysis services for advanced applications. Services will leverage ...
Breaking Biology Technology: