Navigation Links
In Situ Pan-Caspase Assay Kit from CHEMICON

ProductsIn Situ Pan-Caspase Assay Kit from CHEMICON
Company CHEMICON
Item In Situ Pan-Caspase Assay Kit
Price $453.00
Description Apoptosis is an evolutionarily conserved form of cell suicide, which follows a specialized cellular process. The central component of this process is a cascade of proteolytic enzymes called caspases. These enzymes participate in a series of reactions that are triggered in response to pro-apoptotic signals and result in the cleavage of protein substrates, causing the disassembly of the cell. Caspases have been identified in organisms ranging from C. elegans to humans. The mammalian caspases play distinct roles in apoptosis and inflammation. In apoptosis, caspases are responsible for proteolytic cleavages that lead to cell disassembly (effector caspases), and are involved in upstream regulatory events (initiator caspases). An active caspase consists of two large and two small subunits that form two heterodimers which associate in a tetramer. In common with other proteases, caspases are synthesized as precursors that undergo proteolytic maturation, either autocatalytically or in a cascade by enzymes with similar specificity. Caspase enzymes specifically recognize a 4 or 5 amino acid sequence on the target substrate which necessarily includes an aspartic acid residue. This residue is the target for cleavage, which occurs at the carbonyl end of the aspartic acid residue. Caspases can be detected via immunoprecipitation, immunoblotting techniques using caspase specific antibodies, or by employing fluorochrome substrates which become fluorescent upon cleavage by the caspase.
Info CHEMICONCHEMICON
CHEMICON International, Inc.
28820 Single Oak Drive
Temecula, CA 92590
Customer Service: 800-437-7500
Tech Support: 800-437-7500
Fax Number: 800-437-7502
Web Site: http://www.chemicon.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. CaspaTag™ Pan-Caspase In Situ Assay Kit, Sulforhodamine from CHEMICON
2. CaspaTag™ Pan-Caspase In Situ Assay Kit, Fluorescein from CHEMICON
3. In Situ Pan-Caspase Assay Kit, Sulforhodamine from CHEMICON
4. Glutathione-S-Transferase (GST) Colorimetric Assay Kit from Sigma-Aldrich
5. In Vitro Osteogenesis Assay Kit from CHEMICON
6. Mast Cell Degranulation colorimetric Assay Kit from CHEMICON
7. PR Competitor Assay Green from Invitrogen
8. PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
9. Hydrogen Peroxide / Peroxidase Fluorometric (resorufin) Assay Kit, Fluoro H2O2 from BACHEM
10. PPARGamma-Competitor Assay Kit Green from Invitrogen
11. Total antioxidant capacity Colorimetric Assay Kit from Neogen Corporation
The HQ505, 20 OptiGreen filter for the Molecular Imager FX is a band pass filter used for detection of Cy2 and FITC with 532 nm excitation....
... 2-color staining method for labeling DNA breaks ... cells by flow cytometry. The kit contains ... apoptosis in cells, including positive and negative ... reaction and rinsing buffers for processing individual ...
... The ApopTag Red In Situ Apoptosis ... by the indirect TUNEL method, utilizing ... fluorochrome. The kit provides indirect immunofluorescence ... analyzed using either fluorescence microscopy or ...
The sample holders for gels are used to hold gels in place in the multi-sample tray I, which is used with Molecular Imager FX imaging systems....
Biology Products:
(Date:4/11/2017)... No two people are believed to ... York University Tandon School of Engineering and Michigan ... partial similarities between prints are common enough that ... and other electronic devices can be more vulnerable ... in the fact that fingerprint-based authentication systems feature ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), ... End-Use (Transportation & Logistics, Government & Public Sector, Utilities ... Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), ... you looking for a definitive report on the $27.9bn ... ...
(Date:4/5/2017)... , April 5, 2017 Today ... announcing that the server component of the HYPR platform ... for providing the end-to-end security architecture that empowers biometric ... HYPR has already secured over 15 million users ... including manufacturers of connected home product suites and physical ...
Breaking Biology News(10 mins):
(Date:9/22/2017)... , ... September 22, 2017 , ... ... leg ulcers is now being assessed in clinical trials in the United States. ... talk to your nurse or physician or find your nearest participating clinic here ...
(Date:9/21/2017)... ... 21, 2017 , ... Dr. Greg Leyer, Chief Scientific Officer of UAS Labs, ... presentation is at 12:10pm in the Probiotics Resource Center, Mandalay Bay Expo Hall. ... discuss how probiotics have shown impressive data in areas outside the gut including heart ...
(Date:9/21/2017)... ... September 21, 2017 , ... Colpitts Clinical has launched the ... includes new features that facilitate streamlined and compliant communication, file sharing and document ... forefront of medical advancements, they rely on efficiencies to help them address the ...
(Date:9/21/2017)... Jersey (PRWEB) , ... September 21, 2017 , ... ... pharmaceutical and clinical research sector professionals, has announced the addition of 5 new ... 11 training - Compliance with Regulation 21 CFR Part 11 on Electronic ...
Breaking Biology Technology: