Navigation Links
In Situ Pan-Caspase Assay Kit from CHEMICON

ProductsIn Situ Pan-Caspase Assay Kit from CHEMICON
Company CHEMICON
Item In Situ Pan-Caspase Assay Kit
Price $453.00
Description Apoptosis is an evolutionarily conserved form of cell suicide, which follows a specialized cellular process. The central component of this process is a cascade of proteolytic enzymes called caspases. These enzymes participate in a series of reactions that are triggered in response to pro-apoptotic signals and result in the cleavage of protein substrates, causing the disassembly of the cell. Caspases have been identified in organisms ranging from C. elegans to humans. The mammalian caspases play distinct roles in apoptosis and inflammation. In apoptosis, caspases are responsible for proteolytic cleavages that lead to cell disassembly (effector caspases), and are involved in upstream regulatory events (initiator caspases). An active caspase consists of two large and two small subunits that form two heterodimers which associate in a tetramer. In common with other proteases, caspases are synthesized as precursors that undergo proteolytic maturation, either autocatalytically or in a cascade by enzymes with similar specificity. Caspase enzymes specifically recognize a 4 or 5 amino acid sequence on the target substrate which necessarily includes an aspartic acid residue. This residue is the target for cleavage, which occurs at the carbonyl end of the aspartic acid residue. Caspases can be detected via immunoprecipitation, immunoblotting techniques using caspase specific antibodies, or by employing fluorochrome substrates which become fluorescent upon cleavage by the caspase.
Info CHEMICONCHEMICON
CHEMICON International, Inc.
28820 Single Oak Drive
Temecula, CA 92590
Customer Service: 800-437-7500
Tech Support: 800-437-7500
Fax Number: 800-437-7502
Web Site: http://www.chemicon.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. CaspaTag™ Pan-Caspase In Situ Assay Kit, Sulforhodamine from CHEMICON
2. CaspaTag™ Pan-Caspase In Situ Assay Kit, Fluorescein from CHEMICON
3. In Situ Pan-Caspase Assay Kit, Sulforhodamine from CHEMICON
4. Glutathione-S-Transferase (GST) Colorimetric Assay Kit from Sigma-Aldrich
5. In Vitro Osteogenesis Assay Kit from CHEMICON
6. Mast Cell Degranulation colorimetric Assay Kit from CHEMICON
7. PR Competitor Assay Green from Invitrogen
8. PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
9. Hydrogen Peroxide / Peroxidase Fluorometric (resorufin) Assay Kit, Fluoro H2O2 from BACHEM
10. PPARGamma-Competitor Assay Kit Green from Invitrogen
11. Total antioxidant capacity Colorimetric Assay Kit from Neogen Corporation
... System revolutionizes DNA sequencing, delivering sequence data ... Genome Sequencer 20 System includes: ... for library construction, amplification, and sequencing ... assembly The instrument is ...
... Kodak Companys Molecular Imaging Systems group ... Station 4000 Digital Imaging Systems, featuring ... for comprehensive fluorescence, luminescence, radiographic and ... million pixel CCD and 10x optical ...
... It has been demonstrated that oxidative ... disease, and cancer. Oxidative stress is the ... stimuli and physiological antioxidants exist leading to ... physiological response to oxidative stress is through ...
Compound(s) tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential Neurological liabilities of compound...
Biology Products:
(Date:12/6/2016)... , Dec. 6, 2016 Securus Technologies, ... technology solutions for public safety, investigation, corrections and ... announced today a five (5) year funding commitment ... to expand the rehabilitation and reentry support to ... History Established in 2004, the Prison Entrepreneurship Program ...
(Date:12/2/2016)... 1, 2016   SoftServe , a global ... , an electrocardiogram (ECG) biosensor analysis system for ... IoT asset. The smart system ensures device-to-device communication ... wheel and mobile devices to easily ,recognize, and ... As vehicle technology advances, so too must the ...
(Date:11/29/2016)... BioDirection, a privately held medical device company developing novel ... concussion and other traumatic brain injury (TBI), announced today ... the U.S. Food and Drug Administration (FDA) to review ... meeting company representatives reviewed plans for clinical development of ... a planned pilot trial. "We are ...
Breaking Biology News(10 mins):
(Date:12/9/2016)... India , December 9, 2016 According ... & Services (Primer, Probe, Custom, Predesigned, Reagent Equipment), Application (Research, PCR, ... Forecasts to 2021" published by MarketsandMarkets, the global market is expected ... in 2016, at a CAGR of 10.6% during the forecast period. ... ...
(Date:12/8/2016)... ... December 08, 2016 , ... Lajollacooks4u, San Diego’s premier team building events and ... events, new program offerings and company expansion. , This is largely due ... groups of over 30 people. Ever since, Lajollacooks4u has seen significant demand for its ...
(Date:12/8/2016)... AskLinkerReports.com has published a report on Amyloglucosidase Market ... Market Research Report. From a basic outline of the Amyloglucosidase ... covered in the report. This report projects investment feasibility analysis, ... Amyloglucosidase industry. ... , Complete report on ...
(Date:12/8/2016)... Iowa , Dec. 8, 2016 Eurofins announces the ... Food and President of Eurofins Scientific Inc. (ESI). ... with his proven professional and entrepreneurial experience in leading international business ... the US food testing market to uphold Eurofins, status as the ... ...
Breaking Biology Technology: