|Products||Goat Anti-PAX3 Polyclonal Antibody, Unconjugated from GeneTex|
|Item||Goat Anti-PAX3 Polyclonal Antibody, Unconjugated|
|Description|| Goat polyclonal to PAX3|
This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Immunogen: Synthetic peptide: TTLAGAVPRMM, corresponding to N terminal amino acids 2-12 of PAX3.
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