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Glutathione-S-Transferase (GST) Colorimetric Assay Kit from Sigma-Aldrich

ProductsGlutathione-S-Transferase (GST) Colorimetric Assay Kit from Sigma-Aldrich
Company Sigma-Aldrich
Item Glutathione-S-Transferase (GST) Colorimetric Assay Kit
Description Biochem/physiol Actions: Glutathione-S-transferases (GSTs) are a group of enzymes important in the detoxification of many

xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is present in plants, insects, yeast, bacteria, and in most mammalian tissues, especially in the liver, which plays a key role in detoxification
General description: The GST Assay is intended for total GST activity measurement in cell and bacterial lysates, tissue homogenates, and in plasma and erythrocytes lysates. Kit utilizes 1-Chloro-2,4-Dinitrobenzene (CDNB) which is suitable for the broadest range of GST isozymes. Upon conjugation of the thiol group of glutathione to the CDNB substrate, there is an increase in the absorbance at 340 nm.
Info Sigma-AldrichSigma-Aldrich
Sigma-Aldrich Corp.
St. Louis, MO, USA
Customer Service: 800-325-3010
Tech Support: 800-325-5832
Fax Number: 314-771-5757
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NOTE: Price information is approximate list price and actual prices may vary.

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