Navigation Links
Free Activin A ELISA Kit from Diagnostic Systems Laboratories, Inc.

ProductsFree Activin A ELISA Kit from Diagnostic Systems Laboratories, Inc.
Company Diagnostic Systems Laboratories, Inc.
Item Free Activin A ELISA Kit
Description Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone morphogenetic proteins, growth differentiation factors, AMH/MIS (Anti-Mullerian Hormone/Mullerian Inhibiting Substance) and Inhibins.
Activins and Inhibins are structurally related gonadal dimeric glycoproteins defined by their ability to modulate the synthesis and release of follicle-stimulating hormone (FSH) from the anterior pituitary gland. Activins are homo- or heterodimers consisting of A or B subunits producing Activin A, B, and AB, and have been shown to stimulate FSH release. Inhibins are heterodimers consisting of a common a-subunit linked to either a A subunit (Inhibin A) or B subunit (Inhibin B) by disulfide bridges, and in contrast to the Activins, inhibit FSH release. Messenger RNA studies demonstrate that both Inhibin and Activin are most abundant in the ovary and testis, but can be found in a variety of other tissues (2). In addition to their endocrine role, these proteins have been shown to affect the growth and differentiation of a number of cell types, including cultured rat anterior pituitary cells, gonadal and neuronal cell lines, and hematopoietic progenitor and erythroleukemia cells (2).
Two binding proteins have been described for the Activins and Inhibins: Follistatin and a-2 macroglobulin. Activins are bound with high affinity to follistatin with a possible regulatory role, while both inhibins and activins are found to bind reversibly with a2-macroglobulin (3).
Despite numerous studies investigating the circulating levels of the various activin molecules in numerous disease states, no clear physiological roles have been established other than the stimulatory action on pituitary FSH secretion. However, a number of recent studies have indicated that the measurement of Activin may be useful as a predictor of pre-eclampsia (4,5), preterm labor (6) and various oncological conditions (7).
Info Diagnostic Systems Laboratories, Inc.Diagnostic Systems Laboratories, Inc.
Diagnostic Systems Laboratories, Inc.
445 Medical Center Blvd
Webster Texas 77598
Customer Service: (800) 231-7970
Fax Number: (281) 338-1895
Web Site:
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Free Activin AB ELISA Kit from Diagnostic Systems Laboratories, Inc.
2. Free Activin B ELISA Kit from Diagnostic Systems Laboratories, Inc.
3. Rat Anti-Mouse Activin RIB / ALK-4 Monoclonal Antibody, Unconjugated, Clone 207304 from R&D Systems
4. HIV-1 p24 ELISA Kit, Alliance (480 Tests) from PerkinElmer
5. Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.
6. Equine TNF alpha ELISA development Kit, Screening Set from Endogen
7. Staccato Sciclone ELISA Station from Caliper Life Sciences
8. Telomerase ELISA Assay Kit, TRAPEZE from CHEMICON
9. Nuclear Matrix Protein ELISA Kit from Calbiochem
10. Rat TRACP 5b ELISA Kit, TRAPTM from IDS Ltd
11. ELISA Antibody Diluent-Rabbit Polyclonal from AbD Serotec
Proline-serine-threonine phosphatase-interacting protein 2...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
... Goat polyclonal to FbxL7 ... F in which it was originally ... motif that binds SKP1. F-box proteins ... protein ligases called SCFs (SKP1, cullin, ...
Biology Products:
(Date:10/6/2015)... 2015  Maverix Biomics, Inc., a leading genomic ... software portfolio with the debut of its RNA-Seq ... in eukaryotes. The software is integrated into the ... analysis solution that leverages proven open-source algorithms and ... efforts. Garry Nolan,s laboratory at ...
(Date:9/30/2015)... , Sept. 30, 2015  The U.S. Court of ... another key ruling in favor of Crossmatch ™, ... fingerprint scanner company Suprema and its U.S. partner Mentalix ... a trade provision that declares it unlawful to engage ... infringing two of Crossmatch,s patents, the 5,900,993 patent and ...
(Date:9/28/2015)...  The monitoring of vital signs, such as ... an essential component of patient assessment. Changes in ... a patient,s condition. However, in general care areas ... during routine observation rounds only once every four ... these observation rounds, the warning signs can go ...
Breaking Biology News(10 mins):
(Date:10/13/2015)... , October 13, 2015 " ... and Forecast 2015 - 2023 " , the ... and is anticipated to reach US$7.59 bn by 2023, expanding at ... 2023. --> " Microbiology Culture Market - Global ... " , the global microbiology culture market was ...
(Date:10/13/2015)... --      Q BioMed Inc (OTC: QBIO), ... a strategic relationship with Wombat Capital, Ltd., a ... France based strategic and scientific advisory firm.. ... collaborative arrangement gives Q BioMed and its stakeholders access ... as long established pharmaceutical industry relationships. The advisors within ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... ... and distributor of automation systems, material handling solutions and components, is opening its ... I-94 near State Street, the facility is Exotic’s second major expansion in Metropolitan ...
(Date:10/13/2015)... , ... October 13, 2015 , ... ... educational opportunities for school age children in the areas of Science, Technology, Engineering ... sectors of the national economy, and the program aims to increase the number ...
Breaking Biology Technology: