Navigation Links
ATTO-TAG CBQCA Amine-Derivatization Kit from Molecular Probes (Invitrogen)

ProductsATTO-TAG CBQCA Amine-Derivatization Kit from Molecular Probes (Invitrogen)
Company Molecular Probes (Invitrogen)
Item ATTO-TAG CBQCA Amine-Derivatization Kit
Price 
Description Molecular Probes is pleased to offer the ATTO-TAG series of reagents for the ultrasensitive detection of primary amines. Developed by Novotny and collaborators at Indiana University, the ATTO-TAG reagents are similar to the important reagents o-phthaldialdehyde (OPA), naphthalene-2,3-dicarboxaldehyde (NDA) and anthracene-2,3-dicarboxaldehyde, all of which are also available in high purity form from Molecular Probes.

Principle:
ATTO-TAG CBQCA (3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde or CBQCA 1) and ATTO-TAG FQ (3-(2-furoyl) quinoline-2-carboxaldehyde 2) react specifically with primary amines to form conjugates that can be analyzed by electrophoretic or chromatographic methods. Unlike OPA and NDA, ATTO-TAG CBQCA will also react with hydrophilic peptides and amino sugars. The resulting products of CBQCA highly fluorescent 7-aza-1-cyano-5,6-benzisoindoles are maximally excited at 450nm or by the 442 nm spectral line of the He-Cd laser and have emission maxima at ~550 nm. The products of ATTO-TAG FQ are maximally excited at 480 nm or by the 488 nm line of the argon-ion laser and have emission maxima at ~590 nm. In capillary zone electrophoresis (CZE), the sensitivity of detection of ATTO-TAG CBQCA conjugates should be in the attomole range (10-18 moles). The high sensitivity, freedom from background and long-wavelength excitability make these potential reagents for research, diagnostic and forensic applications, including drug analysis. The ATTO-TAG reagents can, of course, be used in HPLC and other modes of chromatography with either absorbance or fluorescence detection. The principal limitation to obtaining ultrasensitive detection using chemical derivatization reagents, including the ATTO-TAG reagents, is that relatively high concentrations of the derivatizing reagent are required to obtain adequate kinetics and sufficient modification of the analyte. A recently described technique employs ATTOTAG FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have been immobilized on Immobilon-CD membranes. This method permits the quantitative derivatization and analysis by capillary electrophoresis of only a few picomoles of the analyte.
Info Molecular Probes (Invitrogen)Molecular Probes (Invitrogen)
PO Box 22010
Eugene, OR 97402-0469

Call Molecular Probes (Invitrogen) to buy products (US and Canada only; other locations use numbers below)
USA Canada 1-541-359-2658
Customer Service: 1-541-465-8300
Fax Number: 1-541-344-6504
Web Site: http://probes.invitrogen.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. ATTO-TAG FQ Amine-Derivatization Kit from Molecular Probes (Invitrogen)
2. ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)
3. Cleland’s Reagent, Molecular Biology Grade from Calbiochem
4. SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)
5. SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)
6. SYBR Green II RNA gel stain*10,000X concentrate in DMSO**special packaging* from Molecular Probes (Invitrogen)
7. AquaMax DW4 from Molecular Devices
8. GenePix Pro Microarray Image Analysis Software from Molecular Devices
9. adenosine 5-O-(3-thiotriphosphate), BODIPY FL conjugated/tagged from Molecular Probes (Invitrogen)
10. Acuity Enterprise Microarray Informatics Software from Molecular Devices
11. SlowFade Antifade Kit from Molecular Probes (Invitrogen)
Mouse monoclonal [4i97] to HLA Class 1 A25 ( Abpromise for all tested applications). Antigen: Full length protein (Human): HLA Class 1 Antigen-A25. Swiss Protein ID: P18462...
Request Info...
Mouse Anti-Human MCAF-(MCP-1)...
Gastric Carcinoma Marker [BY-1 (3H11)]...
Biology Products:
(Date:10/31/2014)... Dr. John Schoggins , Assistant Professor of Microbiology ... New Innovator Award from the National Institutes of Health ... can harbor numerous viruses without becoming sick. , ... is one of 85 awards given under the High ... The New Innovator Awards were created to support highly ...
(Date:10/31/2014)... Thomas Bugnyar and his team have been studying ... the Northern Austrian Alps for years. They observed ... such as grooming and playing. However, they also ... by a third individual. Although in about 50 ... and broke up the two affiliating ravens, intervening ...
(Date:10/30/2014)... available in German . ... our fellow humans to behave socially? This is one ... game theory. Previous studies assumed that it is almost ... from the Max Planck Institute for Evolutionary Biology have ... influence on the cooperative behaviour of others. However, the ...
Breaking Biology News(10 mins):UT Southwestern Microbiologist awarded prestigious NIH research grant 2Together we are strong -- or insufferable 2Together we are strong -- or insufferable 3Together we are strong -- or insufferable 4
... as men, but estrogen might not be the reason. Testosterone, ... findings in the lab of Florida State University researcher Mohamed ... was awarded a five-year, $1.8 million grant from the National ... anxiety. His research team also is working to identify the ...
... industry with an annual turnover of more than SEK 500 ... the malaria medication sold there could be ineffective or even ... a technique that could resolve the situation. In ... It will resemble a small briefcase, in which a pharmacist, ...
... Lizards are an important indicator species for understanding the ... crucial index for evaluating species health, but lizards are ... problem of spontaneous tail loss when lizards are in ... of evaluating these lizards. Dr. Shai Meiri of Tel ...
Cached Biology News:Why does anxiety target women more? FSU researcher awarded $1.8 million grant to find out 2Problem of fake medicines in developing countries could be solved 2Getting a tail up on conservation? 2
(Date:10/31/2014)... (PRWEB) October 31, 2014 Having access ... is an uphill battle in many corners of the ... rural farming community in northwestern Bolivia where many have ... a group from Fairfield University’s School of Engineering has ... Unidad Academica Campesina (UAC), “the united college for the ...
(Date:10/31/2014)... (PRWEB) October 30, 2014 Two ... America were hosted by Charm Sciences at its ... their week in the US, the participants discussed ... control, hygiene management, and process verification, and received ... , This was the first visit to the ...
(Date:10/31/2014)... Dallas, Texas (PRWEB) October 31, 2014 ... report on Global and China Biocides industry. The ... classification, application, and industry chain structure as well ... market analysis, including China’s domestic market as well ... economic situation analysis. The report on the Chinese ...
(Date:10/31/2014)... ENVIRON , an international environmental, ... Dr. Harvey Clewell III has rejoined the firm ... with senior professionals in ENVIRON’s Health Sciences practice. ... The Hamner Institutes for Health Sciences (The Hamner) ... is Director, Center for Human Health Assessment. , ...
Breaking Biology Technology:Fairfield University School of Engineering project reduces illness in rural community 2Fairfield University School of Engineering project reduces illness in rural community 3Charm Sciences Hosts Executives from Latin America for Dairy Safety Executive Seminar 2Biocides Market for International & Chinese Regional Development Analysis Now Available at DeepResearchReports.com 2Biocides Market for International & Chinese Regional Development Analysis Now Available at DeepResearchReports.com 3Internationally recognized health scientist Dr. Harvey Clewell renews association with ENVIRON 2Internationally recognized health scientist Dr. Harvey Clewell renews association with ENVIRON 3