Navigation Links
Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

Few things about growing older are as inevitable and obvious as “going gray,?yet scientists have been unable to explain the precise cause of this usually unwelcome transformation. In a report posted today on the Web site of the journal Science, researchers from Dana-Farber Cancer Institute and Children’s Hospital Boston say they have found the cellular cause of graying hair while investigating the origins of malignant melanoma, the potentially deadly skin cancer.

The scientists traced the loss of hair color to the gradual dying off of adult stem cells that form a reservoir that spawns a continuous supply of new pigment-manufacturing cells, called melanocytes, that give hair its youthful hues. Not only do the non-specialized stem cells become depleted, they also progressively make errors, turning into fully committed pigment cells in the wrong place within the hair follicle, where they are useless for coloring hair. The new findings won’t lead to a scientific alternative to hair dyes any time soon, if ever, even if they do solve a longstanding puzzle about the underlying mechanism of graying. Of more interest to the researchers is the pattern of cellular signals that triggers the death of pigment stem cells, since melanoma is dangerous for the opposite reason –melanocytes proliferate uncontrollably to form tumors and are hard to kill with treatment. “Preventing the graying of hair is not our goal,?emphasizes David E. Fisher, MD, PhD, director of the Dana-Farber Program in Melanoma, and senior author of the Science paper. “Our goal is to prevent or treat melanoma, and to the extent this research is revealing the life cycles of melanocytes, which are the cells that become cancerous in melanoma, we would love to identify a signal that would make a melanoma cell stop growing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also of the melanoma program, are in the Department of Pediatric Oncology at Children’s Hospital Boston as well as at Dana-Farb
'"/>

Source:


Page: 1 2 3

Related biology news :

1. Weizmann Institute suggests that immune cells help to maintain cognition and brain cell renewal
2. Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check
3. Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance
4. BioMed Central welcomes the new National Institutes of Health public access policy
5. Institute for Systems Biology Symposium Addresses Need for Better Computational Tools
6. Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils
7. UC San Diego partners with Venter Institute to build marine microbial genomics cyberinfrastructure
8. Virginia Bioinformatics Institutes launches microbial database
9. Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
10. UCLA AIDS Institute researchers find a peptide that encourages HIV infection
11. Wisconsin scientists grow critical nerve cells
Post Your Comments:
(Date:8/25/2015)... and BELLEVUE, Wash. , ... in advanced robotic systems, announced today it will unveil ... ground vehicle (UGV), at the National Tactical Officers Association ... The Guardian S is the first-ever commercially ... of years of research and in-field trials and is ...
(Date:8/20/2015)... , Aug. 20, 2015   Sensory, ... on improving the user experience and security of ... technologies, today announced that its TrulySecure™ ... authentication software to be FIDO Certified™. ... for compliance with the FIDO UAF (Universal Authentication ...
(Date:8/18/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/9dmm6l/global_biometric ) has ... Authentication & Identification Market: Focus On Modality, Motility ... report to their offering. The ... expected to grow at an estimated CAGR of ... $25 billion (approximately) by 2020 as per the ...
Breaking Biology News(10 mins):Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2
... new study provides support for Darwin,s hypothesis that ... closely related species than those distantly related. While ... contains the strongest direct experimental evidence yet to ... extinction occurred more frequently and more rapidly between ...
... that chytridiomycosis, a rapidly spreading amphibian disease, has reached ... last area in the entire mountainous neotropics to be ... the Panama Amphibian Rescue and Conservation Project, a consortium ... rescue 20 species of frogs in imminent danger of ...
... implementation of the Global Strategy for Plant Conservation," ... Conservation (GPPC) in association with the Secretariat of ... Gardens Conservation International (BGCI). The conference is expected ... share their experiences and further the development of ...
Cached Biology News:New study supports Darwin's hypothesis on competition between species 2New study supports Darwin's hypothesis on competition between species 3Scientists find deadly amphibian disease in the last disease-free region of central America 2Scientists find deadly amphibian disease in the last disease-free region of central America 3Global strategy for plant conservation conference to take place at the Missouri Botanical Garden 2Global strategy for plant conservation conference to take place at the Missouri Botanical Garden 3
(Date:8/31/2015)... ... August 31, 2015 , ... ... most successful food and beverage processors, equipment manufacturers and leaders in the field ... and industrial weighing and formulation for manufacturers of bakery and snacks; beverages; dairy; ...
(Date:8/28/2015)... , August 28, 2015 According ... (Media, Sera, Cryogenic Storage Systems, Thawing Equipment, Alarms), by ... Medicine, Clinical Trials), End User - Global Forecast to ... expected to reach USD 3,731.03 Million by 2020 from ... of 11.65% between 2015 and 2020. ...
(Date:8/28/2015)... ... ... Since the initial launch of FireflySci Inc. (FFS) in early 2015, the company continues to ... such as the Fonz in a lab coat and Large Marge have been posted on ... , FireflySci is proud to be the only cuvette manufacturer is the world ...
(Date:8/27/2015)... , Aug. 27, 2015 The National ... patient,s eyes—and life—were saved by doctors at Vanderbilt University ... with NNFF, NovaBay Pharmaceuticals and Dr. John Crew ... at Seton Medical Center in Daly ... used a breakthrough approach, pioneered by Dr. Crew, that ...
Breaking Biology Technology:METTLER TOLEDO Hosts Food Safety Educational Center at 2015 PROCESS EXPO 2Biopreservation Market Worth 3,731.03 Million USD by 2020 2Biopreservation Market Worth 3,731.03 Million USD by 2020 3Biopreservation Market Worth 3,731.03 Million USD by 2020 4Biopreservation Market Worth 3,731.03 Million USD by 2020 5Cuvette Manufacturer FireflySci Launches Back to School Deals with Complimentary Shipping On All Orders 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3
... , , , , , 7.6.4 ... increment, which can be programmed as desired with every temperature , command, enables ... each cycle. , , With Long PCR, ... extension of the , elongation. , , ...
... , , , , There is ... applied to all PCR amplifications. For example, , depending on ... of the PCRs can differ from each other. Finding the optimal or the , ... , and efficient amplification of a specific target. , ...
... , , , , , ... DNA fragment using the PCR* are an everyday occurrence in the lab. For ... PCR reaction, which hinder, , or even prevent, further ... unequivocal assessment of the PCR result. In such cases, PCR , ...
Cached Biology Technology:PCR Optimization 2PCR Optimization 3Using Gradient PCR to determine the optimum annealing temperature. 2
... Forma Incubated Orbital Shakers combine ... temperature performance and ease of use. ... vibration, allowing the unit to run ... loads. The unit's class-leading temperature range ...
... Xcise is a powerful technology platform that ... analysis. High quality sample preparation can ... , The Xcise is a powerful technology ... throughput proteome analysis. It combines the functions ...
CQCS kit for first KR 4i , (first unit)....
... lower consumption of reagents and increased ... Multidrop 384 is an automated dispenser ... dispensing into 384- and 96-well plates.This ... can easily switch from 96- to ...
Biology Products: