Navigation Links
Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

As you read this, cells in your eye are transmitting information to your brain, while cells in your heart and arteries work just as hard to keep that brain alive. Every one of these cells -- and others throughout the body -- depends on an internal process called endocytosis to keep the flow of cellular nutrients and information healthy and strong.

It's an incredibly important life process, and now researchers at Weill Medical College of Cornell University in New York City have used an exciting new technology to better understand how one key player -- a protein called clathrin -- helps regulate endocytosis like a well-oiled machine. It may also give us insights into the kinds of disease states that can happen when clathrin-regulated endocytosis goes wrong.

The findings, already published online, will appear in the April print edition of Molecular Biology of the Cell, whose editors have chosen to highlight the Weill Cornell research due to its quality and broader significance to the field.

"This is a kind of cellular fine-tuning, and we know that deficits in this fine-tuning can wreak havoc on health," said Dr. Timothy Ryan, Professor of Biochemistry at Weill Cornell Medical College. "It's well known in obesity, for example, that even a tiny change in metabolic rate results in someone becoming obese."

Endocytosis involves the shuttling back and forth of vesicles (sac-like objects) filled with nutrients, neurotransmitters, or other compounds; usually from the cell surface to the cell interior.

Previous work at Dr. Ryan's lab has helped clarify the role of some of the key players in this process, including a ubiquitous protein called clathrin, found in nearly every cell type.

"From our previous work in brain synapses, we've learned that endocytosis is a machine that really runs quite fast, and in this latest study we were trying to figure out what those speed limits are, especially with regard to varying amounts of clathrin
'"/>

Source:Cornell University


Page: 1 2 3

Related biology news :

1. Cornell finds natural selection in humans
2. Cornell researchers find serious fish virus in Northeast for first time
3. Cornell researcher helping develop quick, cheap HIV/AIDS test
4. Cornell lab confirms deadly fish virus spreading to new species
5. Researchers discover way to make cells in the eye sensitive to light
6. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
7. Researchers find how protein allows insects to detect and respond to pheromones
8. Researchers Uncover Key Step In Manufacture of Memory Protein
9. Research advances quest for HIV-1 vaccine
10. Research on Worms Yields Clues on Aging
11. Researchers reveal the infectious impact of salmon farms on wild salmon
Post Your Comments:
(Date:6/30/2015)... 30, 2015 Genisphere announced ... to help further develop Genisphere,s therapeutics capabilities and portfolio. ... having spent much of the last 25 years in ... Bioscience, and Johnson & Johnson. Tom started his career ... Biotech Corporate Finance. He graduated from Dartmouth College with ...
(Date:6/25/2015)... CITY , June 25, 2015  Imagine a ... steps toward a healthier, happier life. That,s exactly what ... designed to do. The cutting-edge, portable health program provides ... real-life solutions to help improve your lifestyle and nutrition. ... awards dinner and gala Wednesday night, USANA,s THA was ...
(Date:6/24/2015)... SAN JOSE, Calif. , June 24, 2015 ... leading developer of human interface solutions, today announced ... fingerprint sensor to provide secure authentication for its ... Having recently reached more than 200 million shipments ... shipment with Sharp reinforces Synaptics, strength, scalability and ...
Breaking Biology News(10 mins):Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3@USANAinc's Personalized Nutrition Program Wins Industry Innovation Award 2Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2
... is infected with hepatitis C virus (HCV). The outcome of ... many of the chronic infections will develop into liver cirrhosis ... hepatitis C, nor is there any approved vaccine for this ... Twenty to fifty percent of HCV infected patients recovers ...
... water samples for the presence of the radioactive element ... to conduct the sampling required by federal regulations. ... of the new testing method. The technique ... Research Institutes (GTRI) Environmental Radiation Center (ERC), and GTRI ...
... be able to tinker with a single amino acid ... them harmless, according to molecular biologists who say the ... cheap method of making vaccines. "We have successfully tested ... Berg professor of biochemistry and molecular biology at Penn ...
Cached Biology News:Who will recover spontaneously from hepatitis C virus infection 2Safe water: simpler method for analyzing radium in water samples cuts testing time 2Safe water: simpler method for analyzing radium in water samples cuts testing time 3Discovery may help defang viruses 2Discovery may help defang viruses 3
(Date:7/2/2015)... Memphis, TN (PRWEB) , ... July 02, 2015 ... ... in the development and manufacturing of surgical instruments in Orthopedics, announced today the ... orthopedic contract-manufacturing and the world's largest provider of surgical instruments to the Spine ...
(Date:7/1/2015)... PARK, N.C. and PARIS ... research firm AgBiome, and Genective, key developer of ... accelerate the discovery of new generations of insect ... for insect control to counter the realities of ... with Genective, aligning AgBiome,s unique insect control technology ...
(Date:7/1/2015)... ... July 01, 2015 , ... The next-generation sequencing (NGS) ... market segments, including the molecular diagnostics industry. BCC Research reveals in its new report ... tests, lower test costs, and a growing need for better diagnostics as part of ...
(Date:7/1/2015)... 1, 2015   Neuraltus Pharmaceuticals, Inc. , a ... groundbreaking drugs to treat neurodegenerative diseases such as ... Robert G. Miller , M.D., Director of the Forbes ... Pacific Medical Center in San Francisco, has been awarded ... million to help fund a Phase 2 clinical ...
Breaking Biology Technology:In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 2In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 3AgBiome and Genective collaborate to create novel insect-resistant crops 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 2Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 4
... MONTREAL and KIEL, Germany, September ... at the Kiel- based Collagen,Research Institute (CRI) have ... (FORTIGEL(R)) in the context of cell experiments.,Last weekend ... congress of the,Osteoarthritis Research Society International (OARSI) in ...
... NATICK, Mass., Sept. 14 Boston Scientific ... it has entered into a co-marketing agreement with Bladder ... solutions for urinary incontinence. Bladder Health Network offers ... and results analysis, helping to ensure that physicians and ...
... Italy, September 14 Health Robotics today reported,that Dr M ... across all of its I.V. Compounding Centers in Malaysia,Singapore, Indonesia, ... due diligence on 2 companies in the field of I.V.,Robotics, ... to RIVA,s,publicly announced multi-year delays in bringing their robot to ...
Cached Biology Technology:Important Step Forward in Osteoarthritis Research: Bioactive Collagen Peptides Stimulate the Regeneration of Cartilage Tissue 2Important Step Forward in Osteoarthritis Research: Bioactive Collagen Peptides Stimulate the Regeneration of Cartilage Tissue 3Boston Scientific's Urology/Gynecology Business Forms Marketing Alliance with Bladder Health Network 2Boston Scientific's Urology/Gynecology Business Forms Marketing Alliance with Bladder Health Network 3Dr M Group Selects Health Robotics' Technology Over RIVA for all of its I.V. Compounding Centers in South East Asia 2Dr M Group Selects Health Robotics' Technology Over RIVA for all of its I.V. Compounding Centers in South East Asia 3Dr M Group Selects Health Robotics' Technology Over RIVA for all of its I.V. Compounding Centers in South East Asia 4
Consists of 4 separate 100mM solutions (ATP,GTP,CTP and UTP pH 7.5) as sodium salts. 98% Pure by HPLC...
Collected from sexually mature, mixed sex, mixed breed cats. Physiochemical constituents are measured to ensure lot-to-lot consistency....
Tracker Datamatrix TRxD reads any 1D and 2D barcodes within 0.5 seconds....
Donor feline serum and plasma...
Biology Products: