Navigation Links
Visceral Leishmaniasis: Successful Vaccine Trial In Dogs

Visceral leishmaniasis, which is the most severe form of that group of diseases, affects 500 000 people in the world each year. It is caused by a protozoan, Leishmania infantum, transmitted by sand fly bites. There is no vaccine for this disease, which can rapidly lead to death if no treatment is given. In the most heavily affected areas, the dog population is hit heavily by infection. It acts as parasite reservoir for humans. Development of a vaccine for dogs could help brake transmission of the disease to humans, by reducing this reservoir. Such prevention treatment has just been tested successfully on dogs by an IRD team in Montpellier, in conjunction with the Rocher veterinary clinic (La Garde, Var) and the biopharmaceutical company Bio Véto Test (La Seyne-Sur-Mer, Var). The first results showed total lasting protection of these animals against the disease, could open the way towards the development of a human vaccine.

Visceral leishmaniasis, which is the most severe form of the leishmaniases, hits an annual total of 500 000 people, mostly in the developing countries. It is caused by the parasite Leishmania infantum. A flagellate protozoan, it uses as vector an insect resembling a midge, the sand fly, colonizing the intestine and then the salivary glands. The female insect feeds on mammals?blood. It can thus pass the parasite on to humans by a single bite. Once in the blood stream, L. infantum passes into particular cells of the immune system, the macrophages. These eventually burst, releasing the parasites which move on to penetrate other cells. The infected subject suffers bouts of fever, anaemia, enlarged spleen and liver, and weight loss. In the absence of treatment, these clinical signs usually announce a fatal outcome.

The sand fly sucks blood from mammals other than humans. This is how, right around the Mediterranean rim, 5 million dogs, a proportion of from 1 to 42 % depending on the area, are affected by visceral leishmaniasis. These anim
'"/>

Source:Institut de Recherche Pour le D茅veloppement


Page: 1 2 3 4

Related biology news :

1. Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
2. Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer
3. Successful cell engineering may lead to mad cow prevention, say researchers
4. Successful transplantation from pig embryos to mice
5. Successful lung cancer surgery not enough to break nicotine dependence in many smokers
6. FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
7. Live Recombinant Adenovirus Vaccine Technique Explored
8. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
9. NIAID Initiates Trial of Experimental Avian Flu Vaccine
10. Study Models Impact Of Anthrax Vaccine
11. New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Visceral Leishmaniasis Successful Vaccine Trial Dogs

(Date:7/2/2015)... 2015 Fingerprint Cards has received an ... FPC1155 from the distributor World Peace Industrial Group (WPI), part ... Asia . Deliveries are planned to take ... used by smartphone manufacturers in Asia . ... communicated revenue guidance of approximately 2,200 MSEK for 2015. ...
(Date:6/26/2015)... SPRINGVILLE, Utah , June 26, 2015 ATL ... assemblies and devices with specialties in single use solutions, headquartered ... acquisition of MedConx, Inc. (a California ... , and San Jose, Costa Rica ). ... Costa Rica with ATL Technology,s existing ...
(Date:6/24/2015)... , June 24, 2015 The biologics safety ... major drivers for the market include growth of the ... new drug launches. Over the years, the number of ... 2001 and 2010, the FDA approved 225 drug applications ... WIPO, Europe accounted for 3,822 ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 3Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 4
... one of the first human studies of its kind, researchers ... A, or BPA, may be related to decreased sperm quality ... to point out that these results are preliminary and more ... BPA on semen in rodents, but none are known to ...
... to cap it, and it could take billions more to ... Mexico is acknowledged the environmental catastrophe of the century. But ... the remaining problems. Prof. Eugene Rosenberg and Prof. ... and Biotechnology are using naturally occurring oil-munching bacteria, grown at ...
... understand how cells work may get a boost from a ... cells. The new technique, developed by a research ... of chemistry Lawrence Miller, provides the clearest, most dynamic view ... specially modified microscope. The finding is reported in ...
Cached Biology News:Sperm may be harmed by exposure to BPA, study suggests 2A nemesis for oil spills 2New tagging technique enhances view of living cells 2
(Date:7/29/2015)... ... 2015 , ... Brady (NYSE:BRC), a global leader in product ... align chemical container labeling with OSHA’s updated Hazard Communication (HazCom) Standard and the ... of an accurate label, and pictogram uses and meanings. , “With changes to ...
(Date:7/29/2015)... , July 29, 2015  Therapath Neuropathology ... announces increased partnerships with VA and Military Medical ... Nerve Fiber Density (ENFD) and Sweat Gland Nerve ... fiber neuropathy ( https://therapath.com/skin ). ... Fiber Density (ENFD) on punch skin biopsy is ...
(Date:7/29/2015)... , July 29, 2015  Indivior PLC (LON: INDV) ... naloxone nasal spray was accepted and received Priority Review ... the treatment of opioid overdose. This naloxone nasal spray ... formulated for optimal absorption into the nasal mucosa. 1 ... training so individuals may be better equipped to help ...
(Date:7/29/2015)... , July 29, 2015 /PRNewswire/ - RepliCel Life ... stage regenerative medicine company, is pleased to announce that ... injector (RCI-02) have been locked.  Prototypes for industrial ... prepare for an application for CE mark clearance ... in 2016. (Photo: ...
Breaking Biology Technology:Brady Announces a New GHS Label Guide 2Neuropathology services for VA and Military health systems 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 3Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 4Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 5RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 2RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 3RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 4RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 5
... Lab to promote collaborative ventures between Belmont,s School of Pharmacy ... ... 1 Cumberland Emerging,Technologies, Inc. (CET) today announced that Belmont ... Laboratory at the CET Life Sciences Center. The Life Sciences,Center, ...
... Laboratories, a leading,global clinical-diagnostics and biomedical-research laboratory ... Maureen Loftus has joined,the company as president ... and Chief Executive Officer, John F. (Jack) ... experience, garnered from more than,a dozen years ...
... Mich., July 1 Neogen Corporation,(Nasdaq: NEOG ... product line used in,animal health and hygiene applications ... includes 14 different product formulations,along with manufacturing process ... terms were not disclosed., The addition of ...
Cached Biology Technology:CET Life Sciences Center Welcomes Belmont University School of Pharmacy as New Tenant 2IBT Laboratories Names Maureen Loftus President and Chief Operating Officer 2IBT Laboratories Names Maureen Loftus President and Chief Operating Officer 3Neogen Acquires Product Line From DuPont Animal Health Solutions 2
... Our Smart Solutions has now entered ... Screening (HCS) by partnering up with Cellomics, ... from the integration of Beckman Coulter‘s automated ... uncovers deeper biological information at the sub-cellular ...
... in conjunction with the EasyCount System to count ... ViaSure Staining Reagent uses a mixture of ready-to-use ... Bromide to identify live and dead cells, respectively, ... 6 Multi-well Slide provides the ability to ...
... laser scanners is the starting point of ... ,Gene expression analysis, SNP (Single Nucleotide Polymorphism) ... the advancement of research in the post-genomics ... formats and sizes. These arrays call for ...
... This kit allows for rapid, convenient, and ... simple bind/wash/elute process utilizes a spin column ... beads for concentration of proteins which were ... are strong ion exchangers, offering high binding ...
Biology Products: