Navigation Links
UAB researchers confirm HIV-1 originated in wild chimpanzees

An international team of scientists, led by researchers at the University of Alabama at Birmingham (UAB), has discovered a crucial missing link in the search for the origin of HIV-1, the virus responsible for human AIDS. That missing link is the natural reservoir of the virus, which the team has found in wild-living chimpanzees in southern Cameroon. The findings provide important clues to how the disease migrated from non-human to human primates, and will be released Thursday (May 25) in ScienceExpress [http://www.sciencemag.org/sciencexpress/recent.dtl] and will be published in an upcoming issue of Science magazine.

Although researchers have long suspected that HIV-1's origins lie in some way with chimpanzee infection through a closely related virus SIVcpz (simian immunodeficiency virus from chimpanzees), only a few captive apes had been found to harbor SIVcpz. In the study, UAB Professor of Medicine Beatrice H. Hahn, M.D., and her team conducted the first-ever molecular epidemiological survey of SIVcpz infection in wild-living chimpanzees in west-central Africa. By analyzing ape fecal samples collected by trackers from the forest floor in remote jungle regions of Cameroon, Hahn and her colleagues were able to detect SIVcpz-specific antibodies and nucleic acids (viral genetic information) in as many as 35 percent of chimpanzees in some ape communities.

The UAB investigators went on to molecularly clone and sequence the complete viral genomes from four individual chimpanzees. According to UAB post-doctoral researcher Brandon Keele, Ph.D., lead author of the report, "this allowed for unprecedented genetic comparisons to be done between HIV-1 and its closest simian virus counterpart." He went on to say that "finding this cluster of naturally infected chimpanzees will allow us to explore the natural history and behavior of SIVcpz in its natural host and help us begin to unravel how and wh
'"/>

Source:University of Alabama at Birmingham


Page: 1 2

Related biology news :

1. NYU researchers simulate molecular biological clock
2. Vital step in cellular migration described by UCSD medical researchers
3. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
4. UCSD researchers maintain stem cells without contaminated animal feeder layers
5. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
6. New protein discovered by Hebrew University researchers
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Agilent Technologies releases automated literature search tool for biology researchers
9. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
10. Yale researchers identify molecule for detecting parasitic infection in humans
11. US life expectancy about to decline, researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: UAB researchers confirm HIV originated wild chimpanzees

(Date:9/18/2014)... September 18, 2014 Elsevier, a world-leading provider ... services, and the Australasian Research Management Society (ARMS), ... scientists at the 5th Scopus Young Researcher of ... earlier today at the National Convention Centre and ... was attended by guests representing Australia,s and New ...
(Date:9/18/2014)... roaches of the fish world, are the ideal animal ... shape. They,ve moved from the ocean into tens of ... each time changing their skeleton to adapt to the ... populations of sticklebacks now have turned up one of ... a simple change in that gene,s regulation in a ...
(Date:9/18/2014)... found clownfish larvae can swim up to 400 kilometres in ... cope with environmental change. , Clownfish spend their entire adult ... babies they must wander the open ocean, says study co-author, ... Coral Reef Studies (Coral CoE) at James Cook University. , ... now we,ve been given a rare glimpse into how far ...
Breaking Biology News(10 mins):Elsevier and Australasian Research Management Society award scientists at Scopus ceremony 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 3Nemo's epic journey to find a new home 2
... Hoboken, N.J.February 19, 2013John Wiley & Sons, Inc., announced today ... Microbial Biotechnology have joined the Wiley Open Access ... open access and free to view, download and share. ... Molecular Medicine has attracted very high quality submissions and ...
... was only something that was necessary to keep your car ... and animals living in cold climates have natural antifreeze proteins ... matter. Without such antifreeze, living matter would suffer from frost ... proteins is one of the major evolutionary routes taken by ...
... Whales are mammals, but they don,t look like the mammals ... tail, no hind legs and no body hair. And inside ... simpler and ,peg like,. A multidisciplinary team of researchers have ... process to investigate how the whale got its teeth. ...
Cached Biology News:Established journals to publish under open access model 2Not just cars, but living organisms need antifreeze to survive 2Not just cars, but living organisms need antifreeze to survive 3How the whale got its teeth 2How the whale got its teeth 3
(Date:9/19/2014)... September 19, 2014 BioTech News ... patents and results of studies and trials.  Companies in ... Company (NYSE: LLY ), Gilead Sciences Inc. ... CELG ) and Arena Pharmaceuticals Inc. (NASDAQ: ARNA) ... developing prodrug therapeutics for the treatment of cancer, announced ...
(Date:9/19/2014)... -- Dublin ... the addition of the  "Micro Market Monitor : ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , , ,The ... segments in the chromatography market. The market was ... to reach $2.0 billion by 2019, at a ...
(Date:9/18/2014)... USA (PRWEB) September 18, 2014 Bipartisan ... of a bill designed to stimulate development and commercialization ... is being praised by leaders of SPIE, the ... the Revitalizing American Manufacturing and Innovation (RAMI) Act, now ... bill’s authors have said they are optimistic that it ...
(Date:9/18/2014)... 18, 2014 /PRNewswire-iReach/ -- DeepResearchReports.com adds "2014 Deep ... Industry" and "2014 Deep Research Report on Global ... research database. Photo - http://photos.prnewswire.com/prnh/20140918/147058 ... on Global and China Acetic Acid Industry" is ... China and Global Acetic Acid ...
Breaking Biology Technology:Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 3Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 4Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 5Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 6Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 7Micro Market Monitor : Global Pre-packed Chromatography Columns 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4
... In conjunction with,its third quarter 2007 earnings release (expected to ... CVD ) is pleased to invite you to,listen to ... the Internet on Thursday, October 25 at 9:00 a.m. ET. ... and Slide Presentation When: October 25, 2007, ...
... Pharmasset, Inc.,(Nasdaq: VRUS ) has entered into ... Subject to certain terms and conditions of,the agreement, Horizon ... At its option, Pharmasset may receive a second loan ... loan of $10 million by November 30, 2008,provided conditions ...
... Inc.,(Nasdaq: COHR ) today announced that, as anticipated, ... Determination letter indicating that,the Company is not currently in ... Rules 4350(e) and 4350(g) due to,its failure to hold ... September 30, 2007. The notice stated that the failure ...
Cached Biology Technology:Pharmasset Accesses up to $30 Million of Working Capital 2Pharmasset Accesses up to $30 Million of Working Capital 3Coherent, Inc. Receives Expected Letter from NASDAQ 2
PEG 8000, Molecular Biology Grade...
...
... (HDAC) Antibody Sampler Kit Kit Includes: ... #2062, 40 ul Histone Deacetylase 3 (HDAC3) ... 4 (HDAC4) Antibody, Catalog #2072, 40 ul ... 40 ul Histone Deacetylase 6 (HDAC6) Antibody, ...
Recombinant Mouse Matrilin-4, CF Protein Family: Extracellular Matrix Molecules, Chondrogenesis Markers...
Biology Products: