Navigation Links
UAB researchers confirm HIV-1 originated in wild chimpanzees

An international team of scientists, led by researchers at the University of Alabama at Birmingham (UAB), has discovered a crucial missing link in the search for the origin of HIV-1, the virus responsible for human AIDS. That missing link is the natural reservoir of the virus, which the team has found in wild-living chimpanzees in southern Cameroon. The findings provide important clues to how the disease migrated from non-human to human primates, and will be released Thursday (May 25) in ScienceExpress [http://www.sciencemag.org/sciencexpress/recent.dtl] and will be published in an upcoming issue of Science magazine.

Although researchers have long suspected that HIV-1's origins lie in some way with chimpanzee infection through a closely related virus SIVcpz (simian immunodeficiency virus from chimpanzees), only a few captive apes had been found to harbor SIVcpz. In the study, UAB Professor of Medicine Beatrice H. Hahn, M.D., and her team conducted the first-ever molecular epidemiological survey of SIVcpz infection in wild-living chimpanzees in west-central Africa. By analyzing ape fecal samples collected by trackers from the forest floor in remote jungle regions of Cameroon, Hahn and her colleagues were able to detect SIVcpz-specific antibodies and nucleic acids (viral genetic information) in as many as 35 percent of chimpanzees in some ape communities.

The UAB investigators went on to molecularly clone and sequence the complete viral genomes from four individual chimpanzees. According to UAB post-doctoral researcher Brandon Keele, Ph.D., lead author of the report, "this allowed for unprecedented genetic comparisons to be done between HIV-1 and its closest simian virus counterpart." He went on to say that "finding this cluster of naturally infected chimpanzees will allow us to explore the natural history and behavior of SIVcpz in its natural host and help us begin to unravel how and wh
'"/>

Source:University of Alabama at Birmingham


Page: 1 2

Related biology news :

1. NYU researchers simulate molecular biological clock
2. Vital step in cellular migration described by UCSD medical researchers
3. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
4. UCSD researchers maintain stem cells without contaminated animal feeder layers
5. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
6. New protein discovered by Hebrew University researchers
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Agilent Technologies releases automated literature search tool for biology researchers
9. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
10. Yale researchers identify molecule for detecting parasitic infection in humans
11. US life expectancy about to decline, researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: UAB researchers confirm HIV originated wild chimpanzees

(Date:5/11/2015)... 11, 2015  Through a well-rounded UAS delegation representing private ... a strong showing at AUVSI,s Unmanned 2015 conference last week ... Ohio,s UAS industry met with over 200 ... points along the UAS ecosystem. "Our message ... President for Aerospace Rich Knoll . "If you want ...
(Date:5/8/2015)... 8, 2015 Synaptics Inc. (NASDAQ: SYNA ), ... members of the executive management team will present at the ... Media and Telecom Conference Date: May 18, 2015 ... Boston, MA Cowen and Company Technology, ... ET Location: The New York Palace Hotel, New ...
(Date:5/5/2015)... May 5, 2015, NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, reminds investors and media ... Officer, is presenting  at CARTES SECURE CONNEXIONS AMERICA 2015, held ... The three-day conference is organized into a ... in is themed Global Fraud: Where is the Trust ...
Breaking Biology News(10 mins):Ohio Flies High at Unmanned '15, Sets Stage for Ohio UAS Conference 2Synaptics to Present at Upcoming Investor Conferences 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3
... accurate than PSA , Researchers at the University of ... 22 biomarkers that together provide a more accurate screening ... or PSA, test. , The study appears in the ... Medicine. , Researchers looked at blood samples taken from ...
... known for its therapeutic effect on burned or irritated skin, ... as a healthful additive to your fruits and veggies. Researchers ... tropical plant that can be used as an edible coating ... gel, which does not appear to affect food taste or ...
... cell research, producing embryonic-like cells from umbilical cord blood ... life-threatening illnesses, injuries and disabilities. The discovery made during ... Texas Medical Branch and the Synthecon Corporation in the ... ethical and reliable source of human stem cells for ...
Cached Biology News:U-M researchers identify new blood test for prostate cancer 2U-M researchers identify new blood test for prostate cancer 3Aloe vera coating may prolong freshness, safety of fruits and vegetables 2Researchers propose measures to curb lion attacks in Tanzania 2
(Date:5/29/2015)... IRVING, Texas , May 29, 2015 /PRNewswire/ ... company focused on fulfilling the promise of precision ... five studies that demonstrate the clinical utility of ... comprehensive tumor profiling service, in helping to identify ... aggressive tumors. In each of the studies, results ...
(Date:5/29/2015)... May 29, 2015 Translation is frequently listed ... for a good reason--if used in a way that is ... offering of a business product or service offering. , ... have a positive effect on a company's bottom line: , ... anyone in the world can use, why not offer it ...
(Date:5/28/2015)... , May 27, 2015 Research ... addition of Jain PharmaBiotech,s new report ... their offering. An increasing use ... industries is anticipated. Nanotechnology will be applied ... from formulations for optimal delivery to diagnostic ...
(Date:5/28/2015)... LAWRENCEVILLE, N.J. , May 28, 2015 ... announced that it has received commitments from two institutional ... million of the Company,s common stock in an at-the-market ... warrants to purchase common stock. The Company ... pursuant to which the Company agreed to sell an ...
Breaking Biology Technology:Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 2Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 3Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 4Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 5Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 6Three Ways Translation Can Help Businesses Grow 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 3Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 3
... a new market research report is available in its catalogue: , ... Global Nucleic Acid Testing Industry , , ... , , , ... in US$ Million. Annual estimates and forecasts are provided for the period 2006 through 2015. ...
... 1b/2a trial included , , , ... RVX , , , ... CALGARY, AB , June 22 /PRNewswire-FirstCall/ - Resverlogix Corp. ("Resverlogix" ... an oral presentation highlighting the novel features of the Company,s lead drug RVX-208 ...
... ,, Panel discussion with Georgetown experts to address biotechnology, ... , , ... week, the National Institutes of Health and the Food and Drug Administration ... of personalized medicine -- treatments tailored to match a person,s genetic make-up. ...
Cached Biology Technology:Reportlinker Adds Global Nucleic Acid Testing Industry 2Reportlinker Adds Global Nucleic Acid Testing Industry 3Reportlinker Adds Global Nucleic Acid Testing Industry 4Reportlinker Adds Global Nucleic Acid Testing Industry 5Reportlinker Adds Global Nucleic Acid Testing Industry 6Reportlinker Adds Global Nucleic Acid Testing Industry 7Reportlinker Adds Global Nucleic Acid Testing Industry 8Reportlinker Adds Global Nucleic Acid Testing Industry 9Reportlinker Adds Global Nucleic Acid Testing Industry 10Resverlogix Scientific Data Presented at EAS Congress 2Resverlogix Scientific Data Presented at EAS Congress 3Resverlogix Scientific Data Presented at EAS Congress 4Pebbles Along the 'Path' to Personalized Medicine 2Pebbles Along the 'Path' to Personalized Medicine 3Pebbles Along the 'Path' to Personalized Medicine 4
... System is intended for use in the ... an in-house validated in vitro nucleic acid ... • The CHEMICON ... capture assay designed to detect amplified nucleic ...
... these culture chambers produce cell yields in ... range and are useful alternatives to multiple ... mechanical • strength and structural integrity • ... Certified nonpyrogenic and sterilized by gamma irradiation, ...
BD BioCoat Collagen IV 150 mm Culture Dishes...
Gridded Cell Culture Petri Dish (20 mm molded in base), tissue-culture treated...
Biology Products: