Navigation Links
Study reveals dramatic difference between breast cancers in US and Africa

A study comparing, for the first time, breast cancers from Nigeria, Senegal and North America has found that women of African ancestry are more likely to be diagnosed with a more virulent form of the disease than women of European ancestry.

Researchers from the University of Chicago, working with colleagues at the University of Calabar in Nigeria and the University of North Carolina, found that breast cancers in African women produce a different pattern of gene expression. Tumors from African women -- from three locations in Nigeria and one in Senegal -- are more likely to originate from a different group of cells within the breast and often do not present the molecular targets that form the basis of many standard therapies.

"We have known for a long time that breast cancer is not one disease and that it may be somehow different in Africa," said study author Funmi Olopade, M.D., professor of medicine and director of the Center for Clinical Cancer Genetics at the University of Chicago. "But there was no real sense of how much of that was biology and how much was environment. Now we have clear evidence that nature plays an important role. These tumors are biologically quite different in ways that make this a worse disease."

"The discovery means we have to rethink how soon and how often we screen for breast cancer in women at risk for the most aggressive type of breast cancer, as well as how we prevent it and how we treat it," she added. "The guidelines were developed based on our deep knowledge of breast cancer in older women of European ancestry, but our results mean that much of the U.S. and European data simply do not apply to the types of breast cancer we most commonly see in African women."

The researchers studied the pattern of gene expression -- a measure of which genes were turned on and active -- in breast cancer tissue from 378 women in Nigeria and Senegal. They compared the results with a database of breast cancer tissue from
'"/>

Source:University of Chicago Medical Center


Page: 1 2 3 4

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
3. UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims
4. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
5. Study Links Ebola Outbreaks To Animal Carcasses
6. Breakthrough Microarray-based Technology for the Study of Cancer
7. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
8. Study finds more than one-third of human genome regulated by RNA
9. Leukemia Drug Breakthrough Study In New England Journal Of Medicine
10. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
11. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
Post Your Comments:
(Date:3/17/2015)... Minn. , March 17, 2015 ... technology company specializing in clinical study management systems, ... be in attendance at ARENA,s Outsourcing in Clinical ... NC.  This event provides an excellent forum for ... easy-to-use, flexible and affordable software-as-a-service (SaaS) eClinical technology ...
(Date:3/17/2015)... March 17, 2015  MecklerMedia Corporation (OTCQX: MECK) ... for service robots ever held in ... on May 11-13, 2015 at the Javits Convention ... the event include: Acorn Product Development; Axis NJ; ... Kinova Robotics; Littler; NewBotic Corporation; Neya Systems LLC; ...
(Date:3/12/2015)... , March 12, 2015 IriTech, a leading ... member of the Texas Instruments Design Network, announced today ... has demonstrated its IriShield USB MK2120U device during a ... for pension distribution. The iris scanner ... be marketed in India through ...
Breaking Biology News(10 mins):Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3
... Springer and the Italian Society for Ultrasound in Medicine and ... the Journal of Ultrasound , starting in 2013 with ... is the official journal of SIUMB. It will be available ... formerly published by Elsevier. The Journal of Ultrasound ...
... SkyBiometry , a new company providing cloud-based ... today as a spin-off of Neurotechnology , a ... computer vision technologies for more than 20 years. In ... cloud-based face detection and recognition API based on a ...
... animals ever to walk the Earth but why were they ... South Africa suggested that this was due to the nature of ... of favour with many dinosaur researchers. Now Liverpool John Moores University,s ... St Andrews, Scotland, argue that this idea still has legs. ...
Cached Biology News:Springer will collaborate with the Italian Society for Ultrasound in Medicine and Biology 2Neurotechnology Launches SkyBiometry Spin-off Company to Deliver SaaS Biometric Identification and Feature Analysis 2Neurotechnology Launches SkyBiometry Spin-off Company to Deliver SaaS Biometric Identification and Feature Analysis 3Was the sauropod dinosaurs' large size due to plant food? Scientists argue old idea still has legs 2
(Date:3/30/2015)... 2015  Naldemedine, an investigational peripherally acting mu-opioid ... Co., Ltd., met its primary and secondary endpoints ... the treatment of opioid-induced constipation (OIC) in adult ... Study results showed that naldemedine (0.2 mg tablet ... of spontaneous bowel movement (SBM) compared with placebo ...
(Date:3/30/2015)... and MADISON, Wis. , ... Shigehiro Nakajima ,) (TSE: 4901) ("Fujifilm") and Cellular Dynamics ... ICEL ) ("CDI"), a leading developer and manufacturer ... precise specifications, today announced that the two companies have ... CDI via an all-cash tender offer to be followed ...
(Date:3/29/2015)... IRVING, Texas , March 29, 2015 ... presentation of study data in small cell ... profiling using Caris Molecular Intelligence®, the company,s ... of certain gene mutations which may explain ... Researchers found that identification of certain biomarkers ...
(Date:3/29/2015)... 2015 As a symbol of its ... our pharmaceutical manufacturing clients, Whitehouse Laboratories is excited to ... Berkenstock Race Team for the 2015 race season. Success ... but a strong sense of precision and attention to ... success in the quality control testing laboratory. Sponsorship of ...
Breaking Biology Technology:Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 2Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 3Fujifilm Holdings to Acquire Cellular Dynamics International, Inc. 2Fujifilm Holdings to Acquire Cellular Dynamics International, Inc. 3Fujifilm Holdings to Acquire Cellular Dynamics International, Inc. 4Fujifilm Holdings to Acquire Cellular Dynamics International, Inc. 5Fujifilm Holdings to Acquire Cellular Dynamics International, Inc. 6Fujifilm Holdings to Acquire Cellular Dynamics International, Inc. 7Fujifilm Holdings to Acquire Cellular Dynamics International, Inc. 8Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 2Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 3Whitehouse Laboratories Reaffirms Commitment to Speedy Results – Renews Sponsorship of Berkenstock Racing Team 2
... Oct. 22 /Xinhua-PRNewswire/ -- Olympus Capital Holdings Asia ... an agreement to,sell Arysta LifeScience Corporation, the world,s ... an enterprise value of,approximately JPY 250 billion (US$2.2 ... Olympus Capital, a leading middle market private,equity firm ...
... AMDL, Inc. (Amex:,ADL), headquartered in Tustin, California, ... through its wholly owned subsidiary Jade,Pharmaceutical Inc. ... in the development, manufacture and marketing of ... that its,management will present on November 7, ...
... Safety Experts Investigating New Cases of Chagas, Disease ... via Bug Bites & Blood Transfusions, ANAHEIM, Calif., Oct. ... Drug Administration licensed the first blood-screening test,for Chagas, disease, some ... donor exposure to the parasite known to cause,this serious and ...
Cached Biology Technology:Olympus Capital Announces Agreement to Sell Arysta LifeScience Corporation 2Olympus Capital Announces Agreement to Sell Arysta LifeScience Corporation 3AMDL to Present its China Success Story at Rodman & Renshaw 9th Annual Healthcare Conference 2Blood Donations in U.S. Testing Positive for Chagas' Disease 2Blood Donations in U.S. Testing Positive for Chagas' Disease 3Blood Donations in U.S. Testing Positive for Chagas' Disease 4
RAT ANTI MOUSE TCR V BETA 7:RPE Immunogen: T-cell lymphoma TK1...
... Rhesus Serum • Rhesus serum is ... and 5-7 years of age. Available ... Heparin (Na) N-06: K2EDTA ... (Na) N-03: Alsevers N-05: ...
Porcine Serum US Origin 6 Months or Older...
SEQUENASE PCR PRODUCT PRE-SEQU, 1 EA. Category: SEQUENASE....
Biology Products: