Navigation Links
Studies on human genome variation provide insight into disease

The International HapMap Project was initiated with the primary goal of facilitating medical studies and understanding the genomic basis for human diseases. To coordinate with the journal Nature's publication describing the HapMap, the journal Genome Research is announcing a special issue entitled "Human Genome Variation," which is entirely devoted to studies using these data to provide insight into human biology and disease.

Predicting pregnancy success

Successful human reproduction and the maintenance of early pregnancy are dependent on a cluster of genes on chromosome 19 called the Luteinizing Hormone/Chorionic Gonadotropin Beta (LHB/CGB). During primate evolution, this cluster actively underwent numerous gene duplications and structural rearrangements, allowing the associated genes to acquire new biological functions.

In this month's issue of Genome Research, Dr. Maris Laan and her colleagues report their analysis of the LHB/CGB cluster in three human populations: European Estonians, African Mandenka, and Chinese Han. They demonstrate how gene conversion was critical for shaping the genetic diversity of this region in humans.

"This study paves the way for examining an individual's potential reproductive success based on sequence variants of the LHB/CGB genes," explains Laan. "We may be able to determine whether an individual is particularly susceptible to spontaneous abortions or reduced gonadal function, for example."

Contact:
Maris Laan, Ph.D.
Research Professor, University of Tartu, Estonia
Phone: +372-53495258
E-mail: maris@ebc.ee

X-ing out hereditary prostate cancer

According to the Prostate Cancer Foundation, one of every six American men develops prostate cancer, making it the most common form of non-skin cancer. Growing evidence suggests that there is a signific
'"/>

Source:Cold Spring Harbor Laboratory


Page: 1 2 3 4

Related biology news :

1. Studies reveal methods viruses use to sidestep immune system
2. Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
3. Studies clarify risk factors for mother-to-child transmission of hepatitis C virus
4. Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety
5. Studies find general mechanism of cellular aging
6. Studies look at how genes affect antipsychotic drug response
7. Studies yield insight into the numerical brain
8. Studies force new view on biology of flavonoids
9. Novel technology detects human DNA mutations
10. Current human embryonic stem cell lines contaminated UCSD/Salk team finds
11. UWs Rosetta software to unlock secrets of many human proteins
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Studies human genome variation provide insight into disease

(Date:2/5/2015)... , Feb. 3, 2015 Despite a ... from industries such as consumer electronics, automotive, storage ... surface mount technology (SMT) screen printers. Innovations in ... control will push the adoption curve up. Meanwhile, ... steady as glue dispensers are indispensable in the ...
(Date:1/22/2015)... Jan. 13, 2015  Today, FreeWavz ( www.FreeWavz.com ), ... crowdfunding campaign on Fundable, https://www.fundable.com/freewavz . FreeWavz ... production capacity to meet customer demand. ... http://photos.prnewswire.com/prnh/20150113/168790 Invented by ...
(Date:1/22/2015)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) a biometric authentication ... success of the Wocket™ smart wallet at CES 2015 in ... as one of the "11 Hot Products at CES" in a review ... So Far" by Newseveryday.com and "The top 10 gadgets from CES 2015" ...
Breaking Biology News(10 mins):End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3
... PORTLAND, Ore. -- Pediatric neuroscientists at Oregon Health & ... use high magnetic field strength MRI to reveal tiny ... using standard MRI. Early, accurate identification of ... delays in therapy and enable physicians to inform families ...
... Steven B. Abramson, MD, senior vice president and vice ... Departments of Medicine and Pathology at NYU Langone Medical ... American College of Rheumatology (ACR) & Association of Rheumatology ... Chicago. The Distinguished Basic Investigator Award is a ...
... the RIKEN Brain Science Institute (BSI) have discovered a ... proteins from the cell. Their findings indicate that the ... the phosphorylation of a protein called p62, opening the ... as Huntington,s disease and Alzheimer,s disease. One of ...
Cached Biology News:First use of high-field MRI in developing brain reveals previously undetectable injuries 2Steven B. Abramson, MD, receives distinguished Basic Investigator Award at ACR 2011 2
(Date:2/27/2015)... , Feb. 27, 2015  Steep Hill, the ... US and internationally, intends to open a full service ... New Mexico , bringing advanced scientific tools and ... Steep Hill is currently the only laboratory ... conduct potency and contaminant testing in order to meet ...
(Date:2/26/2015)... , Feb. 26, 2015 S&P Capital ... Factual Stock Report coverage on MabVax Therapeutics Holdings Inc ... is a clinical stage biotechnology company focused on the ... medical needs in the treatment of cancer. MabVax has ... on the protective immune responses generated by patients who ...
(Date:2/26/2015)... MOUNTAIN VIEW, Calif. , Feb. 26, 2015 /PRNewswire/ ... appointment of Kate Black as Privacy Officer ... international, federal, and state privacy laws as well as ... and regulatory team, she will be responsible for reviewing, ... for customers in the U.S. and abroad. She joined ...
(Date:2/26/2015)... LEXINGTON, Mass., Feb. 26, 2015   Synageva ... a biopharmaceutical company developing therapeutic products for rare ... and provided 2015 goals, other key objectives, and ... conference call today at 4:30 p.m. EST to ... business update.  To participate in today,s call by ...
Breaking Biology Technology:Steep Hill First to Receive Provisional Approval to Establish Laboratory Services for Cannabis Testing in State of New Mexico 2S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 2S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 3S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 4S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 523andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2Synageva BioPharma Reports 2014 Full Year Financial Results 2Synageva BioPharma Reports 2014 Full Year Financial Results 3Synageva BioPharma Reports 2014 Full Year Financial Results 4Synageva BioPharma Reports 2014 Full Year Financial Results 5Synageva BioPharma Reports 2014 Full Year Financial Results 6Synageva BioPharma Reports 2014 Full Year Financial Results 7Synageva BioPharma Reports 2014 Full Year Financial Results 8Synageva BioPharma Reports 2014 Full Year Financial Results 9
... Intercell,s IXIARO, the first licensed vaccine against Japanese ... -- This final decision follows the positive opinion ... in December 2008VIENNA, April 2 Intercell AG ... to prevent Japanese Encephalitis, IXIARO(R), has been approved ...
... for detection of methicillin-resistant Staphylococcus aureus for better patient ... its new LightCycler(R) test for the detection of methicillin-resistant ... the CE Mark, allowing it to be sold for ... Advanced Test is a qualitative in vitro ...
... - Conference Call Scheduled for Today at 5:00 p.m. ... Sunesis Pharmaceuticals, Inc. (Nasdaq: SNSS ) ... fiscal year ended December 31, 2008.Total revenue for the ... a net loss of $37.2 million. As of December ...
Cached Biology Technology:Intercell Announces European Approval of New Vaccine, IXIARO(R), to Prevent Japanese Encephalitis 2Intercell Announces European Approval of New Vaccine, IXIARO(R), to Prevent Japanese Encephalitis 3Intercell Announces European Approval of New Vaccine, IXIARO(R), to Prevent Japanese Encephalitis 4Roche to Introduce New LightCycler(R) MRSA Advanced Test in the EU 2Roche to Introduce New LightCycler(R) MRSA Advanced Test in the EU 3Roche to Introduce New LightCycler(R) MRSA Advanced Test in the EU 4Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 2Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 3Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 4Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 5Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 6Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 7Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 8Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 9Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 10Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results 11
Roll of Mesh 5m x 25cm...
... Beacon 2000 Fluorescence Polarization System is ... and assay development. Standard Beacon 2000 ... System uses a quartz-halogen lamp that ... 360-700 nm. It accommodates all applications ...
Preparation Note: Prepared essentially by method of Singer, T.P., J. Biol. Chem., 174, 11 (1948). Quality Clarifier: Contains lipase Unit Definition: One unit will hydrolyze 1.0 μmole of p-ni...
... Tris buffer, pH 10.2 give activity approx. ... Assays in diethanolamine buffer, pH 9.8 give ... buffer system. Protein determined by Biuret Physical ... Preparation Unit Definition: One unit will hydrolyze ...
Biology Products: