Navigation Links
Studies on human genome variation provide insight into disease

The International HapMap Project was initiated with the primary goal of facilitating medical studies and understanding the genomic basis for human diseases. To coordinate with the journal Nature's publication describing the HapMap, the journal Genome Research is announcing a special issue entitled "Human Genome Variation," which is entirely devoted to studies using these data to provide insight into human biology and disease.

Predicting pregnancy success

Successful human reproduction and the maintenance of early pregnancy are dependent on a cluster of genes on chromosome 19 called the Luteinizing Hormone/Chorionic Gonadotropin Beta (LHB/CGB). During primate evolution, this cluster actively underwent numerous gene duplications and structural rearrangements, allowing the associated genes to acquire new biological functions.

In this month's issue of Genome Research, Dr. Maris Laan and her colleagues report their analysis of the LHB/CGB cluster in three human populations: European Estonians, African Mandenka, and Chinese Han. They demonstrate how gene conversion was critical for shaping the genetic diversity of this region in humans.

"This study paves the way for examining an individual's potential reproductive success based on sequence variants of the LHB/CGB genes," explains Laan. "We may be able to determine whether an individual is particularly susceptible to spontaneous abortions or reduced gonadal function, for example."

Contact:
Maris Laan, Ph.D.
Research Professor, University of Tartu, Estonia
Phone: +372-53495258
E-mail: maris@ebc.ee

X-ing out hereditary prostate cancer

According to the Prostate Cancer Foundation, one of every six American men develops prostate cancer, making it the most common form of non-skin cancer. Growing evidence suggests that there is a signific
'"/>

Source:Cold Spring Harbor Laboratory


Page: 1 2 3 4

Related biology news :

1. Studies reveal methods viruses use to sidestep immune system
2. Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
3. Studies clarify risk factors for mother-to-child transmission of hepatitis C virus
4. Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety
5. Studies find general mechanism of cellular aging
6. Studies look at how genes affect antipsychotic drug response
7. Studies yield insight into the numerical brain
8. Studies force new view on biology of flavonoids
9. Novel technology detects human DNA mutations
10. Current human embryonic stem cell lines contaminated UCSD/Salk team finds
11. UWs Rosetta software to unlock secrets of many human proteins
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Studies human genome variation provide insight into disease

(Date:6/30/2015)... HATFIELD, Pa. , June 30, 2015 ... joined the company as CEO to help further develop ... a wealth of partnering experience, having spent much of ... companies including Therakine, Amgen, Baxter Bioscience, and Johnson & ... a focus on Technology and Biotech Corporate Finance. He ...
(Date:6/25/2015)... 25, 2015  TAKE Solutions Ltd., a global business ... United States Patent and Trademark Office (USPTO) for its ... TAKE Solutions, Clinical Accelerators to reduce the time taken ... to standardization without the accelerators), thus reducing time to ... At the heart of the patented Clinical Data ...
(Date:6/24/2015)... 2015 Biometry authentication provider KeyLemon today ... solution one face in. Logo ... face in, entering the expanding biometric authentication market ... biometric answer to the password problem. With advanced ... with KeyLemon, one face in allows users to ...
Breaking Biology News(10 mins):Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3TAKE Solutions Awarded Patent By USPTO 2KeyLemon Announces Partnership With Biometric Password Solution onefacein 2
... is participating in a large-scale, multi-center clinical trial in ... substance, in high doses, can slow the progression of ... million people in the United States. "At present, ... only mask the symptoms they do not alter ...
... have found the "Rosetta Stone" of supervolcanoes, those giant ... massive explosive eruptions that rank among nature,s most violent ... and possibly trigger climatic and environmental effects at ... discovered in the Italian Alps, Sesia Valley by a ...
... 100 billion (1011) neurons, which altogether form about 100 ... mechanism for the generation of this complex wiring pattern ... Hannes Schmidt and Professor Fritz G. Rathjen at the ... have now discovered a molecule that regulates this vital ...
Cached Biology News:Can an over-the-counter vitamin-like substance slow the progression of Parkinson's disease? 2'Rosetta Stone' of supervolcanoes discovered in Italian Alps 2'Rosetta Stone' of supervolcanoes discovered in Italian Alps 3MDC researchers discover molecule responsible for axonal branching 2
(Date:7/26/2015)... Maine (PRWEB) , ... July 26, 2015 , ... ... release of its VALIDATE® ANEMIA calibration verification / linearity test kit. The VALIDATE® ... Each VALIDATE® ANEMIA kit is prepared using the CLSI recommended “equal delta” ...
(Date:7/24/2015)... Pa. , July 24, 2015 Ryan ... been filed in United States District Court for the Northern ... all persons or entities that purchased the common stock of ... ) between July 31, 2014 and June 15, 2015, inclusive ... than September 8, 2015, move the Court for appointment as ...
(Date:7/24/2015)... YORK , July 24, 2015 ... following equities: PDL BioPharma Inc. (NASDAQ: PDLI ), ... (NASDAQ: STEM ), Northwest Biotherapeutics Inc. (NASDAQ: ... ). Free research report on PDL BioPharma can be ... 2015, the NASDAQ Composite ended at 5,146.41, down 0.49%, ...
(Date:7/24/2015)... July 24, 2015 Orexigen Therapeutics, Inc. (Nasdaq: ... for the second quarter 2015 on Thursday, August 6 ... provide a business update and discuss the financial results ... a.m. Eastern Time (5:00 a.m. Pacific Time). ... calling (800) 447-0521 (domestic) or (847) 413-3238 (international), participant ...
Breaking Biology Technology:Maine Standards Company, LLC Announces Release of VALIDATE® ANEMIA Calibration Verification / Linearity Test Kit 2Ryan & Maniskas, LLP Announces Class Action Lawsuit Against Avalanche Biotechnologies, Inc. 2Ryan & Maniskas, LLP Announces Class Action Lawsuit Against Avalanche Biotechnologies, Inc. 3Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 2Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 3Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 4Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 5
... 31 Revotar,Biopharmaceuticals AG., today announced first positive ... pilot study in 14 patients with,stable COPD stage ... of Bimosiamose,twice a day. The study was conducted ... Witt and the Respiratory Institute Wiesbaden, Dr.,Beeh. The ...
... Oct. 31 Amedica Corporation,an orthopedic implants company ... the U.S. Food and Drug Administration,has granted 510(k) ... The Valeo(TM) Cervical Plate system combines features aimed ... The,Valeo(TM) Cervical Plate system is intended for anterior ...
... Md., Oct. 31 Micromet, Inc.,(Nasdaq: MITI ... of,novel, proprietary antibody-based products for cancer, inflammation and,autoimmune ... and,Chief Executive Officer of Micromet, will present at ... Conference in New York, on,Wednesday, November 7, 2007 ...
Cached Biology Technology:Revotar Reports First Positive Clinical Results From Phase IIa Study in COPD 2Micromet to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference on November 7, 2007 2
... Source rat adult and fetal ... $550.00, * T75 plated cells ... * This product requires Celprogen ... M55007-08 and extracellular matrix, * ...
... is a K-12 strain ideally suited as ... high transformation efficiency, blue/white screening capability (with ... result in high yields of excellent quality ... is potentially useful as a stringent host ...
... Purification with an Affinity Chitin-binding Tag) utilizes ... splicing elements (termed inteins) to purify recombinant ... (Figures 1 and 2). This system distinguishes ... its ability to separate a recombinant protein ...
... imaging system from Molecular Devices ... system for automated acquisition and analysis ... screening. ImageXpressULTRA is powered by ... screening acquisition, image storage and analysis. ...
Biology Products: