Navigation Links
Stem cell training program to make its Stanford debut

ties. Many of these molecules only become active once they have had a prenyl group added.

The researchers tested whether their new enzyme could modify a wide range of small aromatic molecules, ranging from plant flavonoids ?for instance, compounds found in hops that give beer its bitter taste or in other plants act as sunscreens, pigments, or antibiotics ?to olivetol, a component in the production of THC, the active ingredient of marijuana. Unlike other previously known prenylation enzymes that only act on a small number of molecules, this new enzyme was able to attach prenyl groups to most of the different aromatic compounds tested. Some of the newly-formed hybrid molecules had previously been found in natural sources, but the enzyme also built some new compounds that had never been seen before.

The key to Orf2’s flexibility seems to reside in the active site, the region of the enzyme where the small aromatic molecules bind. In many enzymes, the structure of the active site only allows one specific molecule to interact with it, like a key fitting into a lock. But the scientists found that Orf2’s active site is a surprisingly spacious barrel-like structure, unlike any protein fold ever seen before. Not only does this wide barrel allow Orf2 to act on such a wide range of aromatic molecules, its discovery could also shed new light on the relationship between an enzyme’s structure, the way it has evolved, and the chemical reactions it is able to carry out.

Although the researchers have not yet had a chance to test the modified molecules to see if their function has changed, they believe that Orf2 could be a powerful tool for creating biologically active compounds that could be used as drugs or as new methods of enhancing the disease-preventative properties of plants. Because the enzyme is able to modify such a wide range of compounds, scientists seeking to develop new drugs could use it in several different ways. If they had no particular end pr
'"/>

Source:


Page: 1 2 3

Related biology news :

1. Exercise training in ordinary people affects the activity of 500 genes
2. Laboratory professionals in Africa receive training under AIDS Relief Plan
3. Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
4. Research finds music training tunes human auditory system
5. Critical role in programmed cell death identified
6. Harmful chemicals may reprogram gene response to estrogen
7. Modification of program enables prediction of gene transcription
8. Rutgers to lead $52.7 million protein research program
9. DOEs Office of Science sets up program to aid scientists displaced by Hurricane Katrina
10. Costly breeding programs for endangered species pay off
11. HIV-infected adults in Botswana respond positively to ARV therapy public treatment program
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Stem cell training program make its Stanford debut

(Date:7/13/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... focused on the growing mobile commerce market, announced ... for BEHAVIORAL-DIRECTED AUTHENTIATION METHOD AND SYSTEM. ... secure method to make payments.  With this patent, ... with its groundbreaking voice-direct payment patent application, with ...
(Date:7/9/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/98rrmr/biometrics_for ... "Biometrics for Banking; Market & Technology Analysis, Adoption ... offering. The adoption for banking purposes ... the forecast is that by 2020 it will ... in delivering biometric systems to the banking industry. ...
(Date:7/9/2015)... Calif. , July 9, 2015 /PRNewswire/ ... leading developer of human interface solutions, today ... the industry,s first fully hardware encapsulated fingerprint ... secure authentication technology is literally off the ... and biometric matching within the fingerprint sensor ...
Breaking Biology News(10 mins):NXT-ID Patents Behavior-Directed Payments 2NXT-ID Patents Behavior-Directed Payments 3NXT-ID Patents Behavior-Directed Payments 4Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 2Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 3
... United States are getting a second life in developing ... the most comprehensive ever done on the topic ... & Technology . The findings may ease growing concerns ... from dismantling and recycling computer components in developing countries. ...
... Hospital (MGH) researchers has developed an innovative way to culture ... to be published in Proceedings of the National Academy ... describe how liver cells grown in a high-oxygen environment and ... to function as they do within the liver. ...
... cells have a different structure and expression in type II ... new study from the Swedish medical university Karolinska Institutet published ... ,epigenetic mutations, might have a key part to play in ... is characterised by a lower sensitivity to insulin in muscles ...
Cached Biology News:A breath of fresh air could improve drug toxicity screening 2
(Date:7/28/2015)... ... ... Xsample 530 sample changer for vials can be used with Anton Paar density ... than 12,000 mPas (internal air) up to 36,000 (external air) – and can process up ... Xsample 530 is its removable magazine, which is easily lifted off its hub and carried ...
(Date:7/28/2015)... July 28, 2015 Seahorse Bioscience, the ... is the provider of XF Technology which is ... research areas. As the links between mitochondrial function ... metabolism is escalating rapidly.   Recently, ... Nature Publishing Group (NPG) featuring XF Technology, including ...
(Date:7/28/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/z54c4k/biomedical ) has ... and Freezers Market - Global Industry Analysis, Size, ... report to their offering. ... been segmented based on applications: hospitals, research laboratories, ... others segment includes applications of biomedical refrigerators and ...
(Date:7/28/2015)... -- Tauriga Sciences, Inc. (OTCQB:  TAUG) or ("Tauriga" or ... that its stockholders approved an increase in the number ... from 1,000,000,000 to 2,500,000,000 at its Special Meeting of ... Offices of Nixon Peabody LLP in Midtown Manhattan (the ... shares of common stock represented either by proxy or ...
Breaking Biology Technology:New Moves in Automatic Sample Handling: Introducing Xsample 530 2XF Technology Used to Demonstrate Feasibility of Stem Cell Regenerative Technique 2XF Technology Used to Demonstrate Feasibility of Stem Cell Regenerative Technique 3Biomedical Refrigerators and Freezers Market Report - Global Industry Analysis 2015 2Biomedical Refrigerators and Freezers Market Report - Global Industry Analysis 2015 3Tauriga Sciences, Inc. Stockholders Approve Increase In Authorized Common Stock 2Tauriga Sciences, Inc. Stockholders Approve Increase In Authorized Common Stock 3
... Dallas , and Boston , getting a first look ... the search for DEMO 2007's demonstrating class is in full swing.) ... quite different from the usual fare of Silicon Valley . ... consumer software, Austin has strong leadership in IT systems management. In ...
... the American population hit the 300 million mark earlier this week. ... is scheduled to hit the 300 million mark sometime Tuesday, and ... baby before he or she is out of the womb. , ... many environmentalists still buy into the doomsday theories of Thomas Malthus, ...
... favorite topic of mine over the years is Japan. In ... pharmaceutical industry and biotech markets (3/10/03, 8/18/03, 3/28/05). I had ... Bio-Jan 2006 Conference in September after a three-year hiatus. ... the 30th anniversary celebration of the Osaka-Chicago sister city relationship, ...
Cached Biology Technology:What makes Silicon Valley so different? 2What makes Silicon Valley so different? 3What makes Silicon Valley so different? 4300 millionth American no cause for eco-alarm 2300 millionth American no cause for eco-alarm 3300 millionth American no cause for eco-alarm 4Japan on the rebound: Implications for Midwest 2Japan on the rebound: Implications for Midwest 3Japan on the rebound: Implications for Midwest 4Japan on the rebound: Implications for Midwest 5Japan on the rebound: Implications for Midwest 6Japan on the rebound: Implications for Midwest 7Japan on the rebound: Implications for Midwest 8Japan on the rebound: Implications for Midwest 9
Mouse monoclonal antibody raised against a partial recombinant CALCOCO2. NCBI Entrez Gene ID = CALCOCO2...
Mouse monoclonal antibody raised against a partial recombinant SCARB2. NCBI Entrez Gene ID = SCARB2...
The F40 pump maintenance kit is used to service one F40 pump of a BioLogic DuoFlow workstation. It includes 2 piston seals, 4 check valves, seal removal tool, and 2 O-rings....
...
Biology Products: