Navigation Links
Stem cell training program to make its Stanford debut

Nature is a seemingly endless storehouse of interesting ?and potentially life-saving ?biological molecules. But tracking down and harvesting those chemicals in their natural form can be time-consuming, expensive and unreliable.

Now Salk scientists have discovered a new way of bringing “bio-prospecting?out of the rainforest and into the lab. Their findings are published in the June 16th edition of the journal Nature.

Stéphane Richard, Joseph Noel and Tomohisa Kuzuyama isolated and examined a totally new enzyme that can mix and match biological chemicals to create a wide range of different molecules that could be used as the basis for new drugs. The enzyme, named Orf2, takes chemical building blocks known as small aromatic molecules and changes them by adding a fat-like molecule called a prenyl group. That modification can have a huge impact on where the aromatic molecule goes within the cell, and what sort of effects it has when it reaches its target.

“When you make that so-called hybrid molecule, all the chemistry associated with the original compound changes,?said Noel. He explained that the addition of a prenyl group, also known as prenylation, produces a relatively large change in the chemical’s biological properties. “The molecule becomes a little bit more greasy, and so the kinds of targets that it might interact with change completely.?/p>

“We actually have in our hands now the ability to do things that a chemist might not be able to do, or if a chemist was able to do it, it could be expensive and time-consuming,?said Noel. “I think it’s a completely novel way to approach the whole area of bio-prospecting and new natural medicines.?/p>

The group was interested in manipulating the properties of small aromatic molecules because these bacteria- and plant-derived compounds are involved in a wide variety of important biological processes. Some are potent cancer-fighting anti-oxidants, while others have antibiotic or anti-fungal proper
'"/>

Source:


Page: 1 2 3

Related biology news :

1. Exercise training in ordinary people affects the activity of 500 genes
2. Laboratory professionals in Africa receive training under AIDS Relief Plan
3. Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
4. Research finds music training tunes human auditory system
5. Critical role in programmed cell death identified
6. Harmful chemicals may reprogram gene response to estrogen
7. Modification of program enables prediction of gene transcription
8. Rutgers to lead $52.7 million protein research program
9. DOEs Office of Science sets up program to aid scientists displaced by Hurricane Katrina
10. Costly breeding programs for endangered species pay off
11. HIV-infected adults in Botswana respond positively to ARV therapy public treatment program
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Stem cell training program make its Stanford debut

(Date:6/16/2015)... /CNW Telbec/ - handyem Inc. and FlowMetric Diagnostics ... of handyem,s HPC-150 portable flow cytometer within FlowMetric ... unprecedented model of mobile laboratory platform is presented ... Pennsylvania Convention Center, ... to 18 th 2015.  By virtue of ...
(Date:6/16/2015)... GOTHENBURG, Sweden , June 16, 2015 ... including all touch fingerprint sensors in the company,s portfolio from ... . Deliveries are planned to mainly take place during the ... manufacturers in Asia . Jörgen ... another evidence of    the   growing interest from smartphone ...
(Date:6/15/2015)... , June 16, 2015 According ... Market by Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, ... to 2020" published by MarketsandMarkets, The Natural Language Processing ... a CAGR of 18.4% for the forecast period 2015-2020. ...   46 F igures spread   through 155 ...
Breaking Biology News(10 mins):handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 2handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 3FPC Receives Order for Touch Fingerprint Sensors of 375 MSEK 2Natural Language Processing Market Worth $13.4 Billion by 2020 2Natural Language Processing Market Worth $13.4 Billion by 2020 3Natural Language Processing Market Worth $13.4 Billion by 2020 4Natural Language Processing Market Worth $13.4 Billion by 2020 5
... Effects of climate change projected this century for ... threaten water supplies, buildings, transportation systems, human health, ... report produced by the University of Oregon,s Climate ... Science & Policy. The authors say that ...
... Earth are fueling the world,s highest-known microbial ecosystems, which ... Socompa volcano in the Andes by a University of ... study shows the emission of water, carbon dioxide and ... Socompa sustains complex microbial ecosystems new to science in ...
... researchers in China have discovered that chicken manure can be ... the International Journal of Environment and Pollution the ... more crude oil than soil lacking the guano. ... China, point out that contamination of soil by crude oil ...
Cached Biology News:Eugene-Springfield face Upper Willamette climate threats 2Eugene-Springfield face Upper Willamette climate threats 3Eugene-Springfield face Upper Willamette climate threats 4Earth's highest known microbial systems fueled by volcanic gases 2Earth's highest known microbial systems fueled by volcanic gases 3Fowl soil additive breaks down crude oil 2
(Date:7/7/2015)... , July 7, 2015  SME,s Advanced Manufacturing ... third-annual "30 Under 30" issue, celebrating young men and ... The July issue of Manufacturing ... professionals and students for their accomplishments. Among the standouts: ... U.S. Air Force on optimizing the topology of flapping ...
(Date:7/7/2015)... (PRWEB) , ... July 07, 2015 , ... CSM, a ... team as Vice President of Finance. Morse has an extensive background in financial management ... to the CSM team. In his new role, Morse will oversee all financial areas ...
(Date:7/6/2015)... Irvine, CA (PRWEB) , ... July 06, 2015 ... ... leader in Personalized Medicine, recently hosted their 2015 bi-annual Pain Management Medical Advisory ... Board met with Proove Biosciences’ executive Research and Development team to discuss new ...
(Date:7/6/2015)... SUNNYVALE, Calif. , July 6, 2015  Viveve Medical, ... announced that Patricia Scheller , Viveve,s Chief Executive Officer, ... present live at VirtualInvestorConferences.com on July 9, 2015. , ... 9, 2015 , , , , TIME:     ... , LINK: , , , http://tinyurl.com/viveve   , ...
Breaking Biology Technology:SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 2SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 3SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 4SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 5CSM Appoints Michael Morse as Vice President of Finance 2Proove Biosciences Gathers Key Opinion Leaders in Pain Management for Medical Advisory Board Meeting in Palm Springs, California 2Proove Biosciences Gathers Key Opinion Leaders in Pain Management for Medical Advisory Board Meeting in Palm Springs, California 3Viveve to Webcast Live at VirtualInvestorConferences.com 2Viveve to Webcast Live at VirtualInvestorConferences.com 3
... Instrumental in Dickinson Mental Health Center,s Ability ... to Track ... Oct. 18 Netsmart Technologies, Inc.,a leading provider of ... today announced that Netsmart customer,Dickinson Mental Health Center ranked ...
... Elekta, a global leader in radiation,oncology and ... at the 49th Annual Meeting of The American ... reduce,treatment times and increase efficiency. The meeting will ... Los Angeles Convention Center (Los Angeles,California, USA). Elekta ...
... Mass., Oct. 18 Alseres,Pharmaceuticals, Inc. (Nasdaq: ... Frank Bobe,Executive Vice President and Chief Business ... at Windhover Information,s 2nd,Annual Therapeutic Area Partnerships ... will be presenting an overview on Alseres ...
Cached Biology Technology:Netsmart Technologies Customer in Pennsylvania Recognized for Achieving Data Benchmarking Milestones 2Elekta Announces New Cancer Care Solutions and Highlights Personalized Efficiency at ASTRO 2007 2Elekta Announces New Cancer Care Solutions and Highlights Personalized Efficiency at ASTRO 2007 3Elekta Announces New Cancer Care Solutions and Highlights Personalized Efficiency at ASTRO 2007 4Alseres Pharmaceuticals, Inc. to Present at Windhover's Therapeutic Area Partnerships Conference 2
Request Info...
Request Info...
Agarose-LE, 250 g. Suitable for soft agarose cloning. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1200 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Request Info...
Biology Products: