Navigation Links
Researchers report breakthrough against world’s deadliest viruses

Scientists from the Public Health Agency of Canada - with assistance from the U.S. Army Medical Research Institute of Infectious Diseases - have developed vaccines against the Ebola and Marburg viruses that have been shown to be effective in non-human primates.

In a study published in this month's Nature Medicine, Canadian researchers Dr. Heinz Feldmann and Dr. Steven Jones of PHAC's National Microbiology Laboratory and Dr. Thomas Geisbert of USAMRIID report that the vaccines have proven 100 percent effective in protecting monkeys against infection from these often deadly viruses.

Monkeys are known to develop hemorrhagic fever symptoms that are similar to those observed in humans infected by these viruses. Demonstrating that these vaccines are safe and effective in monkeys is a promising indicator of their real potential for use in humans.

"When you see the tragedies these viruses cause, it's very frustrating that we can't do more to help people," said Dr. Feldmann, who (along with Dr. Jones and others from PHAC) has been providing on-site rapid diagnostic support to the current Marburg outbreak in Angola. "It'll be some time before we can use these vaccines in the field, but it's satisfying to know that we're getting closer."

According to Dr. Geisbert, this is the first vaccine system, or platform, that has protected nonhuman primates from both Ebola and Marburg. "In addition, the vaccine targets dendritic cells, which are the same cells that Ebola and Marburg attack," said Dr. Geisbert. "These cells are also important in generating a protective immune response. So the vaccine goes exactly where we want it to go."

The study describes how Canadian researchers developed the vaccines by replacing a surface protein in an animal pathogen, called vesicular stomatitis virus, with a surface protein from either the Ebola or Marburg viruses. Following extensive work, including trials with mice and guinea pigs, the PHAC researchers colla
'"/>

Source:US Army Medical Research Institute of Infectious Diseases


Page: 1 2

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
(Date:12/5/2014)... Dec. 4, 2014 Increased emphasis on ... in new testing and inspection technologies. The convergence ... to a range of innovative test solutions. This ... Generation Y, which is generally more inclined towards ... product development strategies of test equipment vendors will ...
(Date:12/4/2014)... , Dec. 3, 2014  Crossmatch™, a ... announced that its DigitalPersona ® Pro Enterprise ... have been deployed throughout First Bank branch locations ... South Carolina and Virginia. First Bank, ... Southern Pines, North Carolina , selected ...
(Date:12/3/2014)... As part of our commitment to offering ... to announce the release of a new reader that ... workforce data that they need. The Atlas ... existing readers. Many such devices have serious shortcomings when ... Older models force users to navigate numerous complicated steps ...
Breaking Biology News(10 mins):Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Inception Technologies to Release New Biometric Reader 2
... average temperatures of the atmosphere are rising; the average ... react sensititvely to these changes. The transitional zones between ... slopes store a huge amount of methane hydrates in ... at low temperatures and under high pressure. When the ...
... levels of hormones that are associated with stress are a ... but recent research on young songbirds found that some elevated ... life and death. The new research concluded that elevated ... response to stress, were related to the movement, feeding, and ...
... at The University of Nottingham have discovered a new ... These new materials could lead to a significant reduction ... device associated infections can lead to systemic infections or ... many commonly used devices including urinary and venous catheters ...
Cached Biology News:Are methane hydrates dissolving? 2For young birds, getting stressed out can be a good thing 2New bacteria-resistant materials discovered 2New bacteria-resistant materials discovered 3
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... BioPharma Corp. (TSX, FSE: "HBP") announced that its registration ... the U.S. Securities and Exchange Commission ("SEC").Accordingly, Helix,s common ... Section 12(g) of the Securities Exchange Act of 1934, ... States allows its shares to be solicited and traded ...
... Corporation (NYSE: BSX ) today announced that ... to stable from negative. In addition, Moody,s upgraded ... Ba2 and its liquidity rating to SGL-2 from SGL-3, ... Moody,s said the revised rating outlook reflects: (1) ...
... March 12 /PRNewswire-Asia/ -- Simcere Pharmaceutical Group,("Simcere" or the ... and supplier,of branded generic pharmaceuticals and manufacturer of the ... financial,results for the quarter and fiscal year ended December ... -- Total revenue increased to RMB 466.9 ...
Cached Biology Technology:Helix BioPharma Form 20-F Registration Statement Declared Effective by SEC 2Helix BioPharma Form 20-F Registration Statement Declared Effective by SEC 3Moody's Raises Boston Scientific's Rating Outlook to Stable 2Moody's Raises Boston Scientific's Rating Outlook to Stable 3Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 2Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 3Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 4Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 5Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 6Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 7Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 8Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 9Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 10Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 11Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 12Simcere Pharmaceutical Group Reports Unaudited Fourth Quarter and Fiscal Year 2008 Results 13
BAI-1 (T-20)...
MOUSE ANTI HUMAN CYTOKERATIN 1-8...
GOAT ANTI HUMAN PSA (ISOFORM 1)...
... peptide derived from the N-terminal region of ... Specificity: Specific for the N-terminus of the ... Dog Rat Mouse (positive controls: MDCK-II A431 ... heart blood vessel and brain mossy fiber ...
Biology Products: