Navigation Links
Protein structure initiative launches new resources for the scientific community

r John Norvell, Ph.D. "By centralizing the availability of these materials, we put valuable resources at researchers' fingertips that can free up time to explore important scientific questions."

To date, the PSI research centers have produced more than 100,000 clones. Norvell expects the current centers to produce a total of 20,000 clones annually.

Knowledgebase

In fall 2007, the PSI will establish a "Knowledgebase" that will serve as a headquarters for structural information generated by its centers. For every protein, scientists will be able to find the best available information about the structure and biological function. The Knowledgebase also will offer experimental details about each stage of the protein structure determination process, regardless of whether the structure was successfully determined. Information about current PSI proteins being solved will be listed. In addition to searching these details, scientists will be able to submit requests for protein structures they'd like the PSI to determine.

The PSI centers will continue to deposit all solved structures in the Protein Data Bank (www.pdb.org), an international structural database. So far, the centers have generated more than 1,700 structures from both simple and complex organisms. The majority of these are novel, sharing little structural resemblance to others in the PDB.

Technology Development

As the four large-scale PSI centers concentrate on churning out structures, the six specialized centers will continue to develop methods and tools that lead to more efficient and successful determination of challenging protein structures, such as membrane proteins and large protein complexes.

Many of the technologies conceptualized during the first phase of the PSI have been commercialized and are already being used in labs both large and small.

Such advances include:

  • T
    '"/>


Source:NIH/National Institute of General Medical Sciences


Page: 1 2 3

Related biology news :

1. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
2. Protein discovery could unlock the secret to better TB treatment
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. An HIV Protein Plays a Surprising Role in Gene Activation
5. Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
6. New SARS Protein Linked To Important Cell Doorway
7. The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
8. PANTHER Protein Classification System Database 5.0
9. Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimers, Parkinsons Disease
10. Newly Discovered Compound Blocks Known Cancer-Causing Protein
11. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
Post Your Comments:
(Date:11/15/2014)... YORK , Nov. 13, 2014  While we may ... technology Doctor McCoy used in "Star Trek" to gain instant ... tools designed to work with smartphones and tablets for monitoring ... of the healthcare world. This may seem a tad Orwellian ... ready to adopt some of these technological opportunities into their ...
(Date:11/7/2014)... Calif. , Nov. 7, 2014  In conjunction with ... Police Departments, The Community Foundation of the Verdugos ... DNA JUSTICE PROJECT," a $250,000 initiative to keep ... initial phase. In its first six months of existence, the ... needed evidence support for local law enforcement. "Because ...
(Date:11/6/2014)... November 6, 2014 - Insilico Medicine, Inc, a ... and age related diseases announced a research collaboration ... cancer, Champions Oncology, Inc (OTC: CSBR). , "There ... personalized medicine, but Champions Oncology,s TumorGraft technology is ... the chemotherapy regimen experimentally generating vast amounts of ...
Breaking Biology News(10 mins):Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4Community Foundation Of The Verdugos Unveils Campaign To Fund Glendale-Burbank DNA Justice Project 2Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2
... advance the field of coastal restoration, The Nature Conservancy and ... agencies and research institutions led by the University of Cambridge ... the first time, the actual biomass (the "living weight") of ... , ,Historical ecology with real numbers, published today ...
... tree growing faster than its neighbor look like from ... of Maryland Center for Environmental Science,s Appalachian Laboratory will ... Nelson were awarded $653,018 from National Aeronautics and Space ... data to find out how the growth rate of ...
... 2012 - The Reed Elsevier Environmental Challenge shortlist was announced ... safe water and sanitation. The winning project will be announced ... Week in Stockholm and featured in the Journal of ... receive a prize of $50,000 with a second place prize ...
Cached Biology News:New report puts real numbers behind history of oyster reefs 2Reed Elsevier Environmental Challenge shortlists 2012 projects 2
(Date:11/26/2014)... 2014 In keeping with the holiday ... bevy of last-minute Thanksgiving savings. The company is offering ... all product lines this holiday weekend as well as ... Friday, and Cyber Monday are right around the corner, ... both loyal customers and those looking to explore their ...
(Date:11/26/2014)... 26, 2014 The Alliance for ... survey of European physicians at the "1 ST ... Biological Therapies" at the Spanish Ministry of Health, ... EuropaBio and the Spanish Bioindustry Association (ASEBIO), included ... from Spanish oncology and rheumatology societies, representatives from ...
(Date:11/26/2014)... (PRWEB) November 26, 2014 PMG Research, ... Board. PMG Research is a network of sites that provide ... to over 2 million patient lives through its partnerships with ... comprised of 11 hub site locations in the Southeastern United ... first term of the board will be held ...
(Date:11/26/2014)... Sunnyvale, CA (PRWEB) November 25, 2014 ... joins forces with RPM Alliance , provider ... and pharmaceutical companies. With the latest addition to its ... only free validated EDC system to India. , ... as a robust and customizable EDC platform which is ...
Breaking Biology Technology:DNA Spectrum Offers Last Minute Thanksgiving Coupons 2DNA Spectrum Offers Last Minute Thanksgiving Coupons 3ASBM Presents European Physicians Survey at Spanish Ministry of Health 2PMG Research Names Medical Advisory Board 2PMG Research Names Medical Advisory Board 3RPM Alliance Joins Clinovo’s CRO Partnership Program, Further Strengthening Its Presence in Southern California and India 2
... throughout the Upper Midwest will have the chance to network ... Wisconsin Early Stage Symposium . , ,The event, to be ... Oct. 19-20. It is being organized by the Wisconsin Technology ... the Wisconsin Entrepreneurs' Network. , ,"When you think about it, ...
... Orleans and Biloxi by Hurricane Katrina has released another type ... making deadly weather even deadlier. The debate wont help last ... prepare us for tomorrows hurricanes. , ,About a month before ... climate researcher at the Massachusetts Institute of Technology published a ...
... Larry Landweber, who was involved in one of the first ... the next stage of the Internet, which has been proposed ... Information Science & Engineering (CISE) branch of the ... may lead to the next generation of the Internet. ...
Cached Biology Technology:Conference will focus on financing of early-stage ventures 2Conference will focus on financing of early-stage ventures 3In the wake of Katrina, more questions than answers about global climate change 2In the wake of Katrina, more questions than answers about global climate change 3Madison professor emeritus will consult on development of 'Internet 2' 2Madison professor emeritus will consult on development of 'Internet 2' 3
Preparation TW--Compatibility: no end cap seals -Hybridization Tube for Hybrigene -Comp Dim: 240 80 mm -Material: borosilicate glass -Mfr Desig: Techne FHB-15...
... top performance with exquisite design. The 96 ... unparalleled temperature uniformity. The instrument has a ... spreadsheet or alternatively in a graphical mode. ... the push of a button and swings ...
...
... provide a rapid and simple method for recovering ... 10 kb) from stained agarose gels or EtBr ... an agarose gel and loaded into the spin ... are a series of membranes and filters that ...
Biology Products: