Navigation Links
Pregnancy hormone key to repairing nerve cell damage

biological mechanism that produces new myelin in the adult brain and spinal cord and identifies prolactin as a potential therapeutic substance for future testing in people with MS.

"Agents promoting remyelination will be beneficial not only for typical demyelinating diseases like MS," says Dr. Fred (Rusty) Gage, of the Salk Institute, "but also for many other neurological disorders, such as spinal cord injuries and stroke." Gage, an international leader in nervous system repair, was not involved in this study.

Subsequent tests of prolactin in animal models of MS will be required before testing of prolactin on humans can take place, but MS researchers are hopeful human trials can take place within the next several years.

"This discovery has the potential to take MS therapy a step further than current treatments that stabilize the disease in its early stages. By promoting repair, which is the goal of prolactin therapy, we have hope of actually improving symptoms in people with MS," says Dr. Luanne Metz, director of the Calgary MS Clinic in the Department of Clinical Neurosciences, University of Calgary and Calgary Health Region.

The study, authored by Weiss, Christopher Gregg, Viktor Shikar, Peter Larsen, Gloria Mak, Andrew Chojnacki and Yong, compared pregnant and virgin female mice of the same age and found that pregnant mice had twice as many myelin-producing cells, called oligodendrocytes, and continued to generate new ones during pregnancy. By chemically destroying myelin around nerve cells, the researchers found that pregnant mice had twice as much new myelin two weeks following the damage as virgin mice and that introducing prolactin mimicked the effects of pregnancy on myelin production and repair in mice that weren't pregnant.

"The results of this study should be well received by people living with MS today," said Dr. William McIlroy, national medical advisor for the Multiple Sclerosis Society of Canada.
'"/>

Source:University of Calgary


Page: 1 2 3

Related biology news :

1. Pregnancy drugs can affect grandkids
2. Female sex hormones play a vital role in defense against sexually transmitted diseases
3. Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
4. Measuring hormone cuts antibiotic use in half in pneumonia patients
5. Alcohol consumption disrupts breastfeeding hormones
6. VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease
7. University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
8. Penguin chicks exposed to human visitors experience spike in stress hormone
9. Suppressing growth hormone in early adulthood may prevent cancer
10. Growth hormone is made in the brain, report scientists
11. Learning and memory stimulated by gut hormone
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Pregnancy hormone key repairing nerve cell damage

(Date:9/22/2014)... fires captured in this image burn in Khabarovsk Krai, a ... of red hotspots, accompanied by plumes of smoke mark active ... to the east towards the Sea of Okhotsk. ... area, swampy forest inhabit the central depression, and deciduous forests ... wildfires are common in Russia in the summer, the 2014 ...
(Date:9/22/2014)... to global warming, larger and larger areas of sea ice ... over in the winter it is thinner and more reduced. ... an acceleration of global warming, because reduced sea ice in ... scientists report. , "If our results are representative, then sea ... take this into account in future global CO2 budgets", says ...
(Date:9/21/2014)... September 22, 2014The story of cowpea (black-eyed peas) is ... world,s biggest problemseven more fascinating is the story of ... wrote Cowpea: The Food Legume of the 21st Century ... management, and use. The book was recently published by ... International Institute of Tropical Agriculture (IITA). , Singh has ...
Breaking Biology News(10 mins):Arctic sea ice helps remove CO2 from the atmosphere 2
... MADISON, WI, JULY 21, 2011 -- Surface water quality ... as well as human needs and recreation. Pasturelands have ... and pathogens in Midwest surface water resources. While poor ... is known about the specific amount of pollution in ...
... program developed by a Penn State synthetic biologist could ... turn bacteria into molecular factories, capable of producing everything ... engineer designs a plane or a car," said Howard ... and chemical engineering. "When designing a biological organism, there ...
... When competing for food and resources, bacteria employ elaborate strategies ... a pathway that allows disease-causing bacteria to attack other bacterial ... aeruginosa is a type of bacteria readily found in ... of settings, including medical devices, body organs and skin wounds. ...
Cached Biology News:Grazing management effects on stream pollutants 2Software helps synthetic biologists customize protein production 2
(Date:9/23/2014)... Cambridge Semantics, the leading provider of ... named in the recent ‘Hype Cycle for Life Sciences ... report details key insights pertaining to the benefits in ... analysts Michael Shanler and Stephen Davies, “The use of ... relationships with scientific stakeholders, and support collaboration and innovation ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 Texas Fertility ... clinic in South Austin, expanding a Central Texas footprint ... San Antonio. The satellite office for the region’s most ... options to the South Austin, Buda, Kyle and San ... and affordable fertility treatment directly to individuals and couples ...
(Date:9/23/2014)... September 23, 2014 Healthcare ... globe will convene at the Society for ... be held October 26-28 in Houston, Texas ... and practice in individualized integrative cancer care. ... nurses, psychologists, nutritionists, naturopaths, acupuncturists, and other ...
(Date:9/22/2014)... who were treated with a statin in the hospital ... likely to survive than those who were not, according ... . This study was conducted by the same researchers ... can improve survival in victims of ischemic stroke., Ischemic ... a blood vessel that blocks blood from reaching areas ...
Breaking Biology Technology:Cambridge Semantics Identified in Gartner’s ‘Hype Cycle for Life Sciences 2014’ Report 2Opening Doors to a Family: Texas Fertility Center Announces Newest Fertility Clinic in South Austin 2Opening Doors to a Family: Texas Fertility Center Announces Newest Fertility Clinic in South Austin 3International Medical Experts to Discuss Latest Integrative Oncology Research and Its Translation to Personalized Clinical Care at 11th International Conference of SIO 2International Medical Experts to Discuss Latest Integrative Oncology Research and Its Translation to Personalized Clinical Care at 11th International Conference of SIO 3Statin use during hospitalization for hemorrhagic stroke associated with improved survival 2
... ABR-Affinity,BioReagents, a leading global antibody manufacturer, ... agreement with Osenses Pty. Ltd., an,Australian-based manufacturer ... extensive portfolio of 100% quality guaranteed research,antibodies, ... Osenses products in the,U.S., Europe and Canada., ...
... alternative bearing surface components, boosting growth, according to ... ... Millennium Research Group (MRG),estimates that the US large-joint reconstructive ... Orthopedic Reconstructive Marketrack(TM),indicates that an uptake in higher-priced products, such ...
... March 3 WaferGen Biosystems,Inc. (OTC Bulletin Board: ... cell biology and stem cell research systems,today announced ... management,team. Kumar Kastury, Ph.D., director of assay development, ... and John McEntee, director,of engineering, has been promoted ...
Cached Biology Technology:ABR-Affinity BioReagents Finalizes Agreement for Distribution of Osenses Antibodies in the U.S., Canada and Europe 2US Large-Joint Reconstructive Implant Market Grew 10% in 2007 2WaferGen Announces Management Team Promotions 2WaferGen Announces Management Team Promotions 3WaferGen Announces Management Team Promotions 4
Purified anti-DNA-PKcs Phosphorylated (Thr2609)...
Peptide-affinity Purified Polyclonal Antibody to Histamine H2 Receptor...
NF kappa B Related Sampler Kit 10g each...
Co-precipitant is free of background polynucleotides,Dnases,Rnases, proteases. 20mg/ml...
Biology Products: