Navigation Links
Pregnancy hormone key to repairing nerve cell damage

The mystery of why multiple sclerosis (MS) tends to go into remission while women are pregnant may be the secret to overcoming the devastating neurodegenerative disease, according to University of Calgary researchers who have shown that a pregnancy-related hormone is responsible for rebuilding the protective coating around nerve cells.

In a paper to be published in the February 21 issue of The Journal of Neuroscience, a team of researchers from the U of C's Faculty of Medicine reports that a study conducted on mice found that the hormone prolactin encourages the spontaneous production of myelin, the fatty substance that coats nerve cells and plays a critical role in transmitting messages in the central nervous system. A collaboration between the laboratories of Drs. Samuel Weiss and V. Wee Yong of the Hotchkiss Brain Institute, the study is the first to determine that prolactin, which increases in the body during pregnancy, is directly responsible for the formation of new myelin in the brains and spinal cords of pregnant mice. Further, when non-pregnant mice with MS-like lesions were injected with prolactin, their myelin was also repaired.

The research was based on evidence that MS, which is more common in women than men, goes into remission when women become pregnant. MS is a neurodegenerative disease where the body's own immune system attacks the myelin surrounding nerves, leading to progressive loss of sensation and movement. MS affects approximately 2.5 million people worldwide and Canadians have one of the highest rates of the disease in the world.

"It is thought that during pregnancy, women's immune systems no longer destroyed the myelin," said Weiss, director of the Hotchkiss Brain Institute and senior author of the study. "However, no previous study has tested whether pregnancy actually results in the production of new myelin, which may lead to improvement of symptoms." The paper's findings represent the first example of a natural,
'"/>

Source:University of Calgary


Page: 1 2 3

Related biology news :

1. Pregnancy drugs can affect grandkids
2. Female sex hormones play a vital role in defense against sexually transmitted diseases
3. Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
4. Measuring hormone cuts antibiotic use in half in pneumonia patients
5. Alcohol consumption disrupts breastfeeding hormones
6. VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease
7. University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
8. Penguin chicks exposed to human visitors experience spike in stress hormone
9. Suppressing growth hormone in early adulthood may prevent cancer
10. Growth hormone is made in the brain, report scientists
11. Learning and memory stimulated by gut hormone
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Pregnancy hormone key repairing nerve cell damage

(Date:9/15/2014)... an unprecedented evolution experiment scientists from GEOMAR Helmholtz ... Institute of Sea Fisheries have demonstrated for the ... algae of the world,s oceans, Emiliania huxleyi ... rising water temperatures. In their study, the researchers ... evolutionary adaptations to these two aspects of climate ...
(Date:9/15/2014)... Ebola virus outbreak in West Africa, which has claimed ... a deeper understanding of the molecular biology of the ... vaccines or antiviral drugs to treat or prevent Ebola ... Virginia (UVA), USA under the leadership of Dr ... structural biologist has obtained the crystal structure of ...
(Date:9/15/2014)... September 15, 2014 Schizophrenia is generally considered to ... many risk factors, both genetic and environmental, with other ... The normal path for brain development is determined by ... and a wide range of environmental factors. , However, ... populations are required in order to map the disturbances ...
Breaking Biology News(10 mins):Small algae with great potential 2Small algae with great potential 3Protein secrets of Ebola virus 2Brain Development in Schizophrenia Strays from the Normal Path 2
... AUSTIN, Texas , April 17, 2013 Vermillion, ... company focused on gynecologic cancers and women,s health, announced the ... with the U.S. Army Medical Research and Materiel Command ... titled, "Cost Reduction Using OVA1 in a Treatment Algorithm ...
... Recent developments in postharvest disease control will be highlighted at ... sponsored by the University of California, Riverside Extension ... run from 8 a.m. to 5 p.m. Tuesday, April 23, and ... Santa Barbara . This year,s conference will include a large ...
... Committee for the Asian hornet, the Vespa velutina ... Community (region), the Charter Provincial Councils, the Beekeeping sector ... aimed at controlling the Vespa velutina populations ... an invasive species from France that preys on bees ...
Cached Biology News:U.S. Army and Vermillion to Assess Health and Economic Benefits of OVA1 as a Standard of Care 2U.S. Army and Vermillion to Assess Health and Economic Benefits of OVA1 as a Standard of Care 3U.S. Army and Vermillion to Assess Health and Economic Benefits of OVA1 as a Standard of Care 4Conference to highlight latest in postharvest pest control 2
(Date:9/15/2014)... An interdisciplinary team of researchers led by Northeastern ... constructing precise inter-nanotube junctions and a variety of ... is facile and easily scalable, which will allow ... nanotube networks for use in applications ranging from ... everything from cars to sports equipment. , Their ...
(Date:9/15/2014)... , Sept. 15, 2014 The chemistry, taste, ... climate, says a new article published by the nonprofit American ... PhD, on climate change and its effects on the phytochemical ... an extensive study conducted by Dr. Ahmed in the ... and has implications for the future of medicinal ...
(Date:9/15/2014)... , Sept. 15, 2014  The second annual ... celebrated October 12-18. A joint initiative of the ... member companies , IPAW is designed to: ... , Recognize the contributions of plasma donors in saving ... plasma protein therapies and rare diseases ...
(Date:9/13/2014)... September 13, 2014 Boehringer Laboratories Inc., ... is proud to announce the successful broadcast of a ... surgeons Leonardo Claros, MD, FACS, FAMBS, and Maher El ... Gastrectomy Calibration System. , This sleeve gastrectomy surgery ... of more than four hundred surgeons from around the ...
Breaking Biology Technology:Northeastern University Researchers Develop Novel Method for Working with Nanotubes 2Tea Taste and Quality Affected by Climate Change 2Tea Taste and Quality Affected by Climate Change 3Tea Taste and Quality Affected by Climate Change 4International Plasma Awareness Week To Celebrate Donors And Spotlight Rare Diseases 2International Plasma Awareness Week To Celebrate Donors And Spotlight Rare Diseases 3Boehringer Laboratories, Inc. Announces Live Surgery Using Innovative System to Calibrate Sleeve Gastrectomy 2
... Dec. 20 Northwest,Biotherapeutics, Inc. (OTC Bulletin ... ("NWBT") announced today that Lonza Group AG ... NWBT,s DCVax(R)-Brain,product and other NWBT DCVax(R) products ... DCVax(R) cancer vaccine products infringed,certain gene expression ...
... teens and adults, HIGHLANDS RANCH, Colo., Dec. 19 ... its treatment services to,include a detox program. The new ... adults, and the hospital has added several new physicians ... abuse and,mental illness)., Teen suicide rates nationally are ...
... PALO ALTO, Calif., Dec. 19 Alexza,Pharmaceuticals, Inc. (Nasdaq: ... V. Barron, MD, FACC to its Board of Directors. ... Medical Officer at Genentech,where he leads the Development organization, ... Dr. Barron joined Genentech in 1996 as a clinical ...
Cached Biology Technology:Lonza Withdraws Majority of Claims in Patent Lawsuit Against Northwest Biotherapeutics 2Lonza Withdraws Majority of Claims in Patent Lawsuit Against Northwest Biotherapeutics 3Lonza Withdraws Majority of Claims in Patent Lawsuit Against Northwest Biotherapeutics 4Highlands Behavioral Health Hospital Unveils New Substance Abuse Detox Program 2Alexza Elects Dr. Hal V. Barron to Its Board of Directors 2Alexza Elects Dr. Hal V. Barron to Its Board of Directors 3
... microPET 220 utilizes utilizies CTI ... leading to superior resolution, sensitivty, and ... the user the flexibility to image ... iamge quality., microPET is a dedicated ...
... been developed to significantly increase the shelf ... Stability is increased at room temperature storage ... This product is subjected to 0.2 micron ... This formulation insures consistently high levels ...
384 Well PCR Plate Carrier for Thermo-Sealer...
... Bead Separation is a powerful tool for ... Typical applications are DNA/RNA or protein purification ... has been fully automated on the Genesis ... Te-MagS. ,In combination with the RoMa ...
Biology Products: