Navigation Links
Pregnancy hormone key to repairing nerve cell damage

The mystery of why multiple sclerosis (MS) tends to go into remission while women are pregnant may be the secret to overcoming the devastating neurodegenerative disease, according to University of Calgary researchers who have shown that a pregnancy-related hormone is responsible for rebuilding the protective coating around nerve cells.

In a paper to be published in the February 21 issue of The Journal of Neuroscience, a team of researchers from the U of C's Faculty of Medicine reports that a study conducted on mice found that the hormone prolactin encourages the spontaneous production of myelin, the fatty substance that coats nerve cells and plays a critical role in transmitting messages in the central nervous system. A collaboration between the laboratories of Drs. Samuel Weiss and V. Wee Yong of the Hotchkiss Brain Institute, the study is the first to determine that prolactin, which increases in the body during pregnancy, is directly responsible for the formation of new myelin in the brains and spinal cords of pregnant mice. Further, when non-pregnant mice with MS-like lesions were injected with prolactin, their myelin was also repaired.

The research was based on evidence that MS, which is more common in women than men, goes into remission when women become pregnant. MS is a neurodegenerative disease where the body's own immune system attacks the myelin surrounding nerves, leading to progressive loss of sensation and movement. MS affects approximately 2.5 million people worldwide and Canadians have one of the highest rates of the disease in the world.

"It is thought that during pregnancy, women's immune systems no longer destroyed the myelin," said Weiss, director of the Hotchkiss Brain Institute and senior author of the study. "However, no previous study has tested whether pregnancy actually results in the production of new myelin, which may lead to improvement of symptoms." The paper's findings represent the first example of a natural,
'"/>

Source:University of Calgary


Page: 1 2 3

Related biology news :

1. Pregnancy drugs can affect grandkids
2. Female sex hormones play a vital role in defense against sexually transmitted diseases
3. Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
4. Measuring hormone cuts antibiotic use in half in pneumonia patients
5. Alcohol consumption disrupts breastfeeding hormones
6. VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease
7. University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
8. Penguin chicks exposed to human visitors experience spike in stress hormone
9. Suppressing growth hormone in early adulthood may prevent cancer
10. Growth hormone is made in the brain, report scientists
11. Learning and memory stimulated by gut hormone
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Pregnancy hormone key repairing nerve cell damage

(Date:7/24/2014)... researchers and patients have hoped that embryonic stem cells ... bodycould provide insight into numerous diseases perhaps even be ... by the inability to transfer research and tools from ... because human ESCs are "primed" and slightly less plastic ... Powell, and Haoyi Wang, who are scientists in the ...
(Date:7/24/2014)... team of researchers led by the University of York ... conservation in the Western Indian Ocean. , The ... point to a revolution in the management of marine ... more than 11,000 km in the region now ... are zones of the seas and coasts designed to ...
(Date:7/24/2014)... , Electric cars are ... sight on the roads of the Scandinavian country so ... vehicle registrations for the second time. This poses a stark ... only a small portion of the market. Of the 43 ... 8000 are electric powered. The main factors discouraging motorists in ...
Breaking Biology News(10 mins):Whitehead Institute researchers create 'naïve' pluripotent human embryonic stem cells 2Western Indian Ocean communities play vital role in conservation 2Nano-supercapacitors for electric cars 2Nano-supercapacitors for electric cars 3
... with targeted antibiotics is often delayed by the ... in culture first. At this week's AVS 53rd ... Lochhead, a bioengineer at the Denver biotechnology company ... single bacterial cells for the most common cases ...
... similar to that in which they exist naturally, proteins ... than those they exhibit when in the static form ... at Baylor College of Medicine in a report in ... In a study using electron cryomicroscopy, Dr. Steven Ludtke, ...
... Biology Center have invented two new gene "chip" technologies ... disease-causing mutations in the 97 percent of the genome ... DNA microarray technology, one of the two new chips, ... in the genome where so-called jumping genes have landed ...
Cached Biology News:Lab-on-a-chip could speed up treatment of drug-resistant pneumonia 2Lab-on-a-chip could speed up treatment of drug-resistant pneumonia 3Taking 'chips' to the next level of gene hunting 2Taking 'chips' to the next level of gene hunting 3
(Date:7/24/2014)... 24, 2014  Neogen Corporation (Nasdaq: NEOG ... its potential revenue from new rodenticide research are premature. ... analysts on July 22, 2014, Neogen,s CEO commented about ... research. "It was my intent Tuesday at ... of a new type of rodenticide, but certainly not ...
(Date:7/24/2014)... July 24, 2014  Spherix Incorporated (SPEX) -- an ... monetization of intellectual property, today announced that the Company ... June 30, 2014 on Monday, August 18, 2014 for ... a.m. ET on Monday, August 18, 2014 to discuss ... the company,s CEO, Anthony Hayes . ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 International research ... announced that its biobanking project, Provia Laboratories , ... its growing Advisory Board. Scott Wolf , CEO ... have Dr. Vaught onboard with Provia’s ever-expanding Advisory Board. ... that Provia’s management team brings to this field, should ...
(Date:7/23/2014)... July 23, 2014 /PRNewswire-iReach/ -- Think Drinks are a ... the long term. They are the first functional focus ... energy as an alternative to the temporary fix associated ... Indiegogo on July 29, 2014, with hopes to raise ... Photo - http://photos.prnewswire.com/prnh/20140723/129697 ...
Breaking Biology Technology:Neogen comments on SenesTech 2Spherix Schedules Shareholder Update Call 2Provia Laboratories Adds Dr. Jim Vaught, Ph.D., Former Chief of BBRB, to Advisory Board 2Provia Laboratories Adds Dr. Jim Vaught, Ph.D., Former Chief of BBRB, to Advisory Board 3Provia Laboratories Adds Dr. Jim Vaught, Ph.D., Former Chief of BBRB, to Advisory Board 4truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2
... , , , 77.6.6 Sample cooling ... If sensitive samples should remain cooled until the PCR takes place, the , ... ways: , , , ... Adapt an initial program and connect via a "LINK" command. , ...
... , , , 7.6.4 Long PCR , ... programmed as desired with every temperature , command, enables a , ... , With Long PCR, this function can be ... elongation. , , ...
... , , , There is obviously ... to all PCR amplifications. For example, , depending on the ... of the PCRs can differ from each other. Finding the optimal or the , ... and efficient amplification of a specific target. , ...
Cached Biology Technology:7 Programming 2PCR Optimization 2PCR Optimization 3
... 4200A can be upgraded to the GenePix ... scans, analyzes, and saves results for up ... email when the batch is complete. Line-by-line ... warped slides. GenePix Pro gives you complete ...
... Maximize the value of your microarray data ... support you need from consultation to extensive ... date methods. Utilize our expertise in combination ... from your own microarray experiments., ,Normalization and ...
... Maximize the value of your microarray ... offer the support you need from ... the most up to date methods. ... the Gene Expression Profiling Service or ...
... CLS number is a new ... match Cornings product number. If ... order under the old Sigma-Aldrich ... service for assistance. Material: ...
Biology Products: