Navigation Links
Patterns in genome organization may partially explain how microbial cells work

ial patterns in the arrangement of most sequenced microbial genomes. They related the degree of organization in each genome they studied to various characteristics specific to each species.

"Bacterial chromosomes may have something like ZIP codes that fix groups of genes to certain locations within the cell where they are most needed," said Timothy E. Allen, a member of Palsson's team at UCSD who is currently an assistant professor of biomedical engineering at the University of Virginia. He said the surprising organization begs the question of what it means. The sequence order of bacterial genomes most likely affects the way in which the DNA is compressed, often more than 1,000-fold, to fit within the confines of the cell. "In some cases, it might suggest that a genome is arranged into relatively large physically distinct coils inside the cell, but nobody knows for certain," Allen said. "One of the take-home messages of our study is that we need to develop more ways to measure the location of specific genes within individual cells."

Palsson's team included Allen, recent Ph.D. graduate Nathan D. Price, and Ph.D. candidate Andrew R. Joyce. They downloaded the sequences of the 161 prokaryotic genomes from the CBS Genome Atlas Database and analyzed regions of each genome for the relative amount of four basic building blocks of DNA, the density of genes and expression level of those genes, and other factors.

To detect patterns in those features, they used wavelet analysis, a statistical technique used to identify patterns in geophysical data such as significant warming of the surface of the ocean off South America that causes El Niño climatic events. The wavelet analysis of bacterial genomes yielded "scalograms," maps colored to elucidate the strength of a variety of periodicities associated with chromosome position. Just as the wavelet analysis identified significant increases in sea surface temperatures; it also revealed nonrandom patterns in th
'"/>

Source:University of California - San Diego


Page: 1 2 3

Related biology news :

1. Man and mouse share genome structures
2. Whole genome fine map of rice completed
3. Study finds more than one-third of human genome regulated by RNA
4. A bacterial genome reveals new targets to combat infectious disease
5. Scientists decipher genome of fungus that can cause life-threatening infections
6. Highly adaptable genome in gut bacterium key to intestinal health
7. Fleshing out the genome
8. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
9. wFleaBase: the Daphnia genome database
10. NHGRI targets 12 more organisms for genome sequencing
11. Chimp genome reveals a retroviral invasion
Post Your Comments:
(Date:1/22/2015)... and Markets ( http://www.researchandmarkets.com/research/wxdglm/global_wearable ) has ... Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, ... report to their offering. , ... be worn on the user,s body and have ...
(Date:12/22/2014)... , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, announces ... Apollo Robbins for the 2015 International CES debut of ... Robbins will be at the NXT-ID booth January 6th ...
(Date:12/19/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has ... America Perimeter Security Systems Market" report to their offering. ... North American perimeter security market is estimated to grow at ... U.S. market holds a larger share in this market, ...
Breaking Biology News(10 mins):Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3
... 2008 -- Rice University bioengineer Jennifer West is being ... highest scientific honors, the O,Donnell Award from The Academy ... The O,Donnell Awards, given for excellence in medical, scientific ... and an inscribed statue. West, a pioneer in the ...
... University Program in Biodesign have released a review ... medical device regulation in the United States. ... of the Journal of Medical Devices, highlights the ... and underscores the complexity of the approval process ...
... out of the University of Alberta for those who may have ... medical researchers have found a way to reduce the amount of ... from food the body metabolizes, a key discovery that could lead ... 2 diabetes and heart disease related to obesity. In ...
Cached Biology News:Rice's West honored as one of Texas' best researchers 2Rice's West honored as one of Texas' best researchers 3Stanford researchers publish review of US medical device regulation 2Stanford researchers publish review of US medical device regulation 3University of Alberta researchers report breakthrough in lowering bad cholesterol, fatty acid levels 2
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently ... Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... education conference for health care professionals. This year’s pre-conference seminar ... probiotics in health. Dr. Leyer spoke about the emerging topics ...
(Date:1/22/2015)... , Nueva Jersey , 22 de enero de ... Biomedical Research abre hoy su llamada a nominaciones para ... investigación científica ha hecho, o tiene el potencial para ... humana. Las nominaciones se aceptarán hasta el 15 de ...
(Date:1/22/2015)... N.J. , Jan. 22, 2015  Derma Sciences, ... regeneration company focused on advanced wound care, announces ... placental tissues, have been added to the Premier, ... increases the opportunity for the AMNIOEXCEL® and AMNIOMATRIX® ...
(Date:12/24/2014)... , Dec. 24, 2014  Vermillion, Inc. (Nasdaq: ... gynecologic disease, announced today that the Company closed ... Oracle Investment Management, Jack W. Schuler , ... proceeds were $10.5 million, before offering expenses.  The ...
Breaking Biology Technology:El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3
... 20 5AM Ventures, specializing,in seed and early-stage ... expansion of the firm,s investment team with,the appointment ... Ventures,also announced the promotion of two of the ... Andrew McMillan, PhD, to Principal. Drs. Forrest,and McMillan ...
... Cells in Future, ROCKVILLE, Md., Feb. 20 ... that Korean conglomerate, CJ,CheilJedang Corporation (KSE: CJ CheilJedang) has ... Neuralstem,s stem cell-products and,technology after the company completes a ... has purchased $2.5 million worth of Neuralstem,stock at $4.063 ...
... in Women,s Health (NPWH) Encourages Women to Get ... 20 Despite growing awareness of HPV,(human papillomavirus), the ... the National Association of Nurse Practitioners in Women,s,Health (NPWH) ... what it takes,to prevent the disease. Despite the fact ...
Cached Biology Technology:5AM Ventures Announces Expansion of Investment Team: Names Richard Ulevitch Venture Partner; Promotes Kevin Forrest and Andrew McMillan to Principal 25AM Ventures Announces Expansion of Investment Team: Names Richard Ulevitch Venture Partner; Promotes Kevin Forrest and Andrew McMillan to Principal 3Neuralstem Inc. Announces Strategic Investment by Korean CJ CheilJedang Corporation 2Neuralstem Inc. Announces Strategic Investment by Korean CJ CheilJedang Corporation 3Survey Shows Most Women Can't Separate Fact From Fiction When It Comes to Cervical Cancer Prevention 2Survey Shows Most Women Can't Separate Fact From Fiction When It Comes to Cervical Cancer Prevention 3Survey Shows Most Women Can't Separate Fact From Fiction When It Comes to Cervical Cancer Prevention 4
The antibody recognizes the peptide sequence ESESQGPK (aa 441-448) of human class III beta-tubulin specific for neurones....
... Immunogen: Partially purified chicken ... detects vitamin D receptor (VDR) from ... and fish tissues. This antibody ... glucocorticoid receptors. MA1-710 detects both ...
... highly versatile power supply. Capable of producing up ... supply is ideal for PAGE, SDS-PAGE, DNA or ... of small format transfer apparatus. It is designed ... with a continuously variable output in either mode. ...
... a highly compact, extremely reliable and easy to ... one hi-lo range switch control the output, which ... to 250 volts. One two-position switch toggles the ... output current. For maximum safety, the EC105 is ...
Biology Products: