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Outsmarting the smartie bug

hods to monitor the effect of the vaccine and allow us to see if changes of capsular types or increased prevalence of the rarer serotypes result in any increase in disease by serotypes not included in the vaccine.

"We must always be vigilant to changes in the properties of microorganisms when we introduce new vaccines or antibiotics. This catalogue will help us to develop new tools to keep a check on the march of the pneumococcus and is also going to give us fascinating insights into the evolution of the amazing diversity of capsular genes that can be produced by this pathogen"

Researchers are at pains to point out that current vaccines are enormously successful and vaccination plays an essential in protecting all of us. The pneumococcal vaccines have been shown to be safe and very effective at preventing widespread infections and are expected to greatly reduce serious pneumococcal disease in UK children, as they already have done in the USA.

Current research, such as the capsule study described here, is intended to ensure we keep ahead of organisms such as S. pneumoniae.


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Source:Public Library of Science


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