Navigation Links
Outsmarting the smartie bug

ts against 82% of infections in children under five years of age in the UK. This will soon be given to UK children under the age of two. A second, PPV, recognizes 23 capsule types and protects against 96% of the UK's strains but is not effective in infants and is mainly used to protect the elderly.

S. pneumoniae usually lives harmlessly in the air passages and in the first year of life most people are likely to have 'carried' at least one strain. It is passed from person to person by sneezing and other aerosols. However, it occasionally passes from the airways to invade other tissues. This can lead to any one of a range of diseases including meningitis and infections of the sinuses, ear, lungs and blood. Why it switches to become invasive is not known.

The team sequenced all genes required to make all 90 forms of the capsule (more than 1,800,000 letters of genetic code), determined their function and studied their evolution. The work gives the most complete understanding of capsule production in any bacterial species.

The new vaccine will protect children from many of the most common serotypes but monitoring is needed to check whether other serotypes start to cause some disease. It is known that pneumococci can switch their capsular polysaccharide and so, if an invasive strain changes its coat to a form not recognised by the vaccine, it might start to become more prevalent and cause disease.

The catalogue of capsules from all known strains will help in the development of new techniques for monitoring changes in capsule type so researchers can look out for such capsule switching.

"The new vaccine that will be given to UK children is very effective at protecting against serious pneumococcal disease, but it does not protect against disease caused by the rarer serotypes," said Brian Spratt, Professor of Microbiology at Imperial College and a co-author of the study. "The catalogue of capsular genes will help us develop better met
'"/>

Source:Public Library of Science


Page: 1 2 3

Related biology news :

1. New insight into people who see colors in letters and numbers
2. Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
3. New insight into regulation of blood stem cells
4. New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
5. New insights into how Huntingtons disease attacks the brain
6. Gambling monkeys give insight into neural machinery of risk
7. Structures of marine toxins provide insight into their effectiveness as cancer drugs
8. Flies on speed offer insight into the roles of dopamine in sleep and arousal
9. Grasshopper love songs give insight into sensory tuning
10. Studies on human genome variation provide insight into disease
11. Study provides insight into cellular defenses against genetic mutation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Outsmarting the smartie bug

(Date:12/17/2014)... , Dec. 16, 2014 Research and Markets ... addition of the "Global Chemical Sensor Market ... http://photos.prnewswire.com/prnh/20130307/600769 One ... increasing demand for medical sensors in biomedical applications. ... for quick and correct diagnosis during surgical procedures. ...
(Date:12/11/2014)... SALEM, N.C. , Dec. 10, 2014  That blood ... for quite a while. Hypertension – the medical term for ... in the early 1800s, and the inflatable cuff that,s used ... That doesn,t, however, mean there,s nothing new about hypertension, its ... some long-held beliefs about the condition and the best ways ...
(Date:12/10/2014)... 9, 2014 CIE San Diego has launched ... the connective tissue that enhances care coordination among social ... share client-level information; earned a second $1 million grant ... serving seniors aging in community and; will be recognized ... 11 th 4-6p. CIE San Diego ...
Breaking Biology News(10 mins):Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... caused some lethal human epidemics in Central Africa. Research ... from the animal reservoir, which is an any case ... and certain forest antelopes. Results have come from work ... and their partners (1) to shed light on the ...
... at the University of Southern California's Viterbi School ... Ultrasonic Transmission Tomography" (HUTT) system that offers 3D ... those produced by existing commercial X-ray, ultrasound or ... biomedical engineering at the Viterbi School, presented HUTT ...
... Grieg Fry, Ph.D., a scientist from the University of ... the origin and evolution of one of nature's most ... the March issue of the journal Genome Research. , ... Colubroidea, evolved glands for the storage and dispersal of ...
Cached Biology News:Ebola virus: from wildlife to dogs 2Ebola virus: from wildlife to dogs 3Ebola virus: from wildlife to dogs 4A probe, not an echo 2A probe, not an echo 3A probe, not an echo 4Venom doc tracks down snake bioweapons 2
(Date:12/15/2014)... , Dec. 15, 2014  GlassesOff Inc. (OTCBB: GLSO) ... as an independent director of the Company,s Board ... AeroScout and served as its CEO until its acquisition ... a $240 million transaction. Recognized as the inventor of ... leadership, AeroScout provided Wi-Fi -based RFID solutions focused on ...
(Date:12/13/2014)... CHARLOTTE, N.C. (PRWEB) December 13, 2014 ... (UNC Charlotte) spin-out company has changed its name to ... more accurate representation of where we are today,” said ... “We’ve extended our platform’s applications beyond breast cancer diagnostics ... is a reflection of that evolution.” , Founded in ...
(Date:12/13/2014)... The DNA Microarray market market ... is expected to grow at a CAGR of ... the TOC of the DNA Microarray for an ... with help of various tables and figures. , ... market consists of instrument, consumables, and services, where ...
(Date:12/13/2014)... According to population studies: “North Carolina ... and 2030." If a population explosion like that actually ... state in the country. , To that end, North ... of North Carolina Forum on December 16th to ask ... necessary infrastructure in place? Enough clean water? And will ...
Breaking Biology Technology:AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3CanDiag Inc. Expands Product Scope Under a New Name: OncoTab, Inc. 2DNA Microarray Market Is Expected to Grow at a CAGR of 15.2% from 2014 to 2019 - A Report by MicroMarket Monitor 2DNA Microarray Market Is Expected to Grow at a CAGR of 15.2% from 2014 to 2019 - A Report by MicroMarket Monitor 3DNA Microarray Market Is Expected to Grow at a CAGR of 15.2% from 2014 to 2019 - A Report by MicroMarket Monitor 4North Carolina Chamber of Commerce: Asking Questions & Gathering Answers with a Futurist 2
... WORTH, Texas, May 16 George Abercrombie, president,and ... than 200,Fort Worth business leaders today at a ... of a pandemic flu presents businesses with challenges,unlike ... "While businesses are all too familiar with preparing ...
... presented at conference, NATICK, Mass., May 16 ... announced that results from an international,multi-center patient registry ... Direct Visualization System will be presented at,Digestive Disease ... San Diego,CA. Registry results will be announced in ...
... CEDAR KNOLLS, N.J., May 16 Highlighting the,company,s ... current product,pipeline, Michael V. Novinski, President and CEO ... featured in an extensive interview published,recently in The ... ago, TWST interviews the leaders of financial markets, ...
Cached Biology Technology:CEO Addresses Fort Worth Business Leaders About Developing Pandemic and Business Continuity Plans 2CEO Addresses Fort Worth Business Leaders About Developing Pandemic and Business Continuity Plans 3Boston Scientific's SpyGlass(R) Direct Visualization System to Be Prominently Featured at Digestive Disease Week(R) 2Boston Scientific's SpyGlass(R) Direct Visualization System to Be Prominently Featured at Digestive Disease Week(R) 3Boston Scientific's SpyGlass(R) Direct Visualization System to Be Prominently Featured at Digestive Disease Week(R) 4Boston Scientific's SpyGlass(R) Direct Visualization System to Be Prominently Featured at Digestive Disease Week(R) 5Michael V. Novinski, Emisphere President/CEO Featured in the Wall Street Transcript 2Michael V. Novinski, Emisphere President/CEO Featured in the Wall Street Transcript 3
... At the forefront of Agilent analytical solutions ... local area networking (LAN) allows you to ... fast and informed decision making. Just as ... all the flexibility and performance needed for ...
The novel and unique HCTplus delivers unmatched information-rich data-dependent LC/MSn data for todays challenge in proteomics and metabonomics work....
The essence of fluorescence analysis is sensitivity. The high throughput optical system in the RF-5301PC employs a blazed holographic grating, photomultiplier and digital signal processing to provide...
... In Situ Assay Kit is a fluorescent-based ... cells undergoing apoptosis. The kit is for ... diagnostic or therapeutic procedures. CHEMICON®s CaspaTag™ Pan-Caspase ... approach to detect active caspases. The methodology ...
Biology Products: