Navigation Links
Outsmarting the smartie bug

ts against 82% of infections in children under five years of age in the UK. This will soon be given to UK children under the age of two. A second, PPV, recognizes 23 capsule types and protects against 96% of the UK's strains but is not effective in infants and is mainly used to protect the elderly.

S. pneumoniae usually lives harmlessly in the air passages and in the first year of life most people are likely to have 'carried' at least one strain. It is passed from person to person by sneezing and other aerosols. However, it occasionally passes from the airways to invade other tissues. This can lead to any one of a range of diseases including meningitis and infections of the sinuses, ear, lungs and blood. Why it switches to become invasive is not known.

The team sequenced all genes required to make all 90 forms of the capsule (more than 1,800,000 letters of genetic code), determined their function and studied their evolution. The work gives the most complete understanding of capsule production in any bacterial species.

The new vaccine will protect children from many of the most common serotypes but monitoring is needed to check whether other serotypes start to cause some disease. It is known that pneumococci can switch their capsular polysaccharide and so, if an invasive strain changes its coat to a form not recognised by the vaccine, it might start to become more prevalent and cause disease.

The catalogue of capsules from all known strains will help in the development of new techniques for monitoring changes in capsule type so researchers can look out for such capsule switching.

"The new vaccine that will be given to UK children is very effective at protecting against serious pneumococcal disease, but it does not protect against disease caused by the rarer serotypes," said Brian Spratt, Professor of Microbiology at Imperial College and a co-author of the study. "The catalogue of capsular genes will help us develop better met
'"/>

Source:Public Library of Science


Page: 1 2 3

Related biology news :

1. New insight into people who see colors in letters and numbers
2. Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
3. New insight into regulation of blood stem cells
4. New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
5. New insights into how Huntingtons disease attacks the brain
6. Gambling monkeys give insight into neural machinery of risk
7. Structures of marine toxins provide insight into their effectiveness as cancer drugs
8. Flies on speed offer insight into the roles of dopamine in sleep and arousal
9. Grasshopper love songs give insight into sensory tuning
10. Studies on human genome variation provide insight into disease
11. Study provides insight into cellular defenses against genetic mutation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Outsmarting the smartie bug

(Date:9/22/2014)... Additive manufacturing (AM), or 3D printing, has rapidly ... metal components strong enough for structural applications. However, ... as well as quality standards to test the ... technology. Engineers at the University of Pittsburgh,s Swanson ... modeling and simulation (M&S) technology and new qualification ...
(Date:9/22/2014)... be much more useful in homes, if they could ... the world with cameras and lasers, which have difficulty ... hidden in clutter. A complementary way robots can "sense" ... small ultra-high frequency radio-frequency identification (UHF RFID) tags. Inexpensive ... RFID-equipped robot to search a room for the correct ...
(Date:9/22/2014)... wake of the huge King Fire blazing out of ... Fire is burning in steep terrain in the South ... and the Rubicon Canyon, north of the community of ... and burned onto the Tahoe National Forest north of ... to be minimal on Sept. 22 due to thunderstorms ...
Breaking Biology News(10 mins):Pitt engineers receive grants to enhance additive manufacturing 2Pitt engineers receive grants to enhance additive manufacturing 3New RFID technology helps robots find household objects 2New RFID technology helps robots find household objects 3
... a New Zealand snail and its worm parasite makes ... reproduction in the absence of parasites, say Indiana University ... this week,s Current Biology . The scientists, ... Hypothesis" of sex, which suggests sexual reproduction allows host ...
... received a $3 million grant from the National Science ... Festival and fund the creation and growth of Science ... first annual San Diego Science Festival, held March-April 2009. ... San Diego as a national and global leader in ...
... Cornell Medical Center have discovered a new gene fusion that ... results may lead to more accurate prostate cancer testing and ... -- a hybrid gene formed from two previously separated genes ... cells to grow more quickly than normal cells. The ...
Cached Biology News:Parasitic worms make sex worthwhile 2Parasitic worms make sex worthwhile 3UC San Diego's $3 million NSF grant to fund science festivals 2UC San Diego's $3 million NSF grant to fund science festivals 3Newly discovered gene fusion may lead to improved prostate cancer diagnosis 2Newly discovered gene fusion may lead to improved prostate cancer diagnosis 3
(Date:9/22/2014)... Topical BioMedics, Inc., is celebrating 20 years of ... restoring hope an quality of life and contributing to ... of the innovative cellular biomedicines research that made Topricin® ... , The company was founded in 1994 in a ... of research, and Topricin inventor), Aurora Paradise (COO) and ...
(Date:9/22/2014)... Follow us on LinkedIn ... available in abundance in nature. These natural bio-based ... as shells of crustaceans. The significant commercial interest ... the high percentage of nitrogen present compared to ... industries owing to its exclusive properties such as ...
(Date:9/22/2014)... September 22, 2014 Follow ... to stay young has groomed and nurtured anti-aging ... worldwide. Growing emphasis on appearance maintenance is benefitting ... a neurotoxic protein obtained from the bacterium, Clostridium ... in muscle relaxation. With cosmetic indications for botulinum ...
(Date:9/22/2014)... DUBLIN , Sept. 22, 2014 ... the "Global and Chinese Microcrystalline Cellulose Industry Report ... The Global and Chinese Microcrystalline Cellulose Industry Report 2014 ... state of the global microcrystalline cellulose industry with a ... provides a basic overview of the industry including definitions, ...
Breaking Biology Technology:Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 3Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 4Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 5Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 6Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 2Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 3Strong Demand for Non-Invasive Cosmetic Procedures Drives the Global Botulinum Toxin Market, According to New Report by Global Industry Analysts, Inc. 2Strong Demand for Non-Invasive Cosmetic Procedures Drives the Global Botulinum Toxin Market, According to New Report by Global Industry Analysts, Inc. 3Global and Chinese Microcrystalline Cellulose Industry Report 2014 2
... and HILDEN, Germany , May 25, ... , Prime Standard:,QIA) today announced that it has entered ... pursuant to which QIAGEN has acquired all rights,to 70 ... -based specialized,laboratory center for food analysis. The transaction further ...
... Carolina Conceptions, an infertility practice in Raleigh, NC , announces IRB ... newer technology that is growing in demand. While embryo and sperm freezing have ... achieve the same level of success. , ... Unlike fertilized eggs (embryos) and sperm, which thaw well, the larger egg ...
... ... Mills is the latest company to become a tenant at the North ... partnership between David Murdock and the University of North Carolina System. ... Other tenants on the Campus include: Dole Food Inc, Monsanto, NC State ...
Cached Biology Technology:QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 2QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 3QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 4QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 5QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 6QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 7Carolina Conceptions Announces New Egg Freezing Study to Help Women Preserve their Fertility 2General Mills Joins Kannapolis Research Campus 2General Mills Joins Kannapolis Research Campus 3
Bovine Calf Serum...
Collected from animals of U.S. origin.Collected from animals of U.S. origin. *Can be used in cell growth studies and immunoassays. *Sterility tested, * Mycoplasma tested upon request, *Endoto...
NEWBORN CALF SERUM AND PLASMA...
NEWBORN CALF SERUM AND PLASMA...
Biology Products: