Navigation Links
New technology enables faster, more efficient cell harvest: Cell therapy meeting study

A new, transformative filtration-based technology for the isolation and enrichment of cells, a critical first step in the development of therapies to repair or replace diseased or damaged tissues and organs, was found to be more efficient and faster than traditional technology used for cell separation.

These findings were presented today at the International Society for Cellular Therapy (ISCT) annual meeting in Berlin, Germany. The Pall Corporation (NYSE: PLL) Filter Harvest System was found to have the potential to become a valuable tool to help realize the promise of regenerative medicine, a field that scientists believe could produce significant breakthroughs in the treatment of heart disease, cancer, diabetes, bone injury and many other acute and chronic conditions.

Lisa Bradbury, Ph.D., Director, R&D Cell Therapy, Pall Life Sciences, presented data comparing the Pall Filter Harvest System to a traditional open-system, density gradient, centrifuge-based method for isolation of mononuclear cells (MNC) from whole blood. The Pall Filter Harvest System was found to significantly reduce processing time; it can be performed in less than 15 minutes compared to an average processing time of about 2.5 to 4 hours with the Ficoll gradient technique. The Filter Harvest System also exhibited higher yield of MNCs for significantly better recovery (60 to 95 percent) than the Ficoll method.

The Pall Filter Harvest system can be used as a closed system that adheres to Good Manufacturing Practice (cGMP), furthering the ability to comply with increasingly stringent regulations for safe, reproducible and efficacious cell products. In addition to rapid processing, the Pall system can be performed at point of use (operating room). It does not require the addition of laboratory equipment or trained technicians, as the method is easy to learn and use.

"Researchers and companies working in cell therapy expressed the need to find better and easi er ways to isolate and enrich cells that result in higher cell yield, faster processing time, ease of use and are also more likely to meet future regulatory requirements," stated Judy Angelbeck, Ph.D., Senior Vice President, Pall New Technologies. "Pall was able to translate its material science expertise on the interactions between media and cells based on our long-standing leadership in blood filtration to develop this new approach to cell harvesting."

The Pall system can be used to harvest cells from a broad range of biological samples including peripheral blood, bone marrow and umbilical cord blood. The Company is currently working with several companies in applying its filter harvest system to the development of innovative cell-based therapies in a variety of therapeutic areas, including orthopedics.

"We are pleased that Pall technology can play a key role in the revolutionary advances now occurring in medicine by providing researchers with the tools to take novel cell therapies from the laboratory into the clinic, as part of our goal to make cell therapy safe, routine and simple," Dr. Angelbeck added.

Regenerative medicine, which includes cell therapy, is a promising area of scientific research with application in the treatment and cure of a rapidly expanding list of diseases and injuries. Scientists believe cell-based therapies could be used to repair damaged heart muscle following a heart attack, replace skin for burn victims, restore movement after a spinal cord injury and regenerate pancreatic tissue to produce insulin for people with diabetes. Regenerative medicine promises to improve health and quality of life by supporting and activating the body's natural healing abilities.


'"/>

Source:Pall Corporation


Related biology news :

1. Novel technology detects human DNA mutations
2. Novel antiviral technology inhibits RSV infection in mice
3. The BIOS Initiative - open source biotechnology is born
4. Revolutionary nanotechnology illuminates brain cells at work
5. Study: homemade gene expression technology unreliable
6. First technology to remove prions that cause vCJD from blood launched
7. Integration of Agilents MS technology, Proteome Systems software to help scientists in proteomics research
8. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
9. Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs
10. First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
11. Vietnam war technology could aid elephant conservation
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/16/2016)... -- Research and Markets has announced the addition of ... 2021" report to their offering. ... The biometric vehicle access system market, in ... 14.06% from 2016 to 2021. The market is estimated to be ... Million by 2021. The growth of the biometric vehicle access system ...
(Date:12/15/2016)... , Dec 15, 2016 ... Research and Markets has announced the addition ... offering. The report forecasts the global military biometrics market ... The report has been prepared based on an in-depth market ... and its growth prospects over the coming years. The report also includes ...
(Date:12/12/2016)... -- Researchers at Trinity College, Dublin, are opening up ... material with Silly Putty. The mixture (known as "G-putty") ... sense pulse, blood pressure, respiration, and even the ... The research team,s findings were published Thursday in ... Due ...
Breaking Biology News(10 mins):
(Date:1/17/2017)... Jan. 17, 2017   Pulmatrix, Inc . (NASDAQ: ... developing innovative inhaled therapies to address serious pulmonary diseases, ... infections in the lungs of CF patients, PUR1900, has ... by the U.S. Food & Drug Administration. ... to speed the development of novel drugs against important ...
(Date:1/17/2017)...  Only nine percent of U.S. consumers believe pharmaceutical ... 16 percent believe health insurance companies do, according to ... of U.S. adults believe health care providers (such as ... hospitals (23%). "We are in the midst ... , vice president of reputation management and public affairs ...
(Date:1/17/2017)... (PRWEB) , ... January 17, 2017 , ... Pono ... balanced, peaceful and healthy lifestyle, announced today the official launch of its much-anticipated Pono ... the mind. , In development for over a year, the patented Pono ...
(Date:1/17/2017)... ... January 17, 2017 , ... Diagenode, ... recently announced a collaboration with the Heidelberg University Hospital and the German Cancer ... preparation, following the company’s successful launch of its CATS (Capture and Amplification ...
Breaking Biology Technology: