Navigation Links
New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

A special type of MRI scan that measures the flow of water molecules through the brain can help doctors determine early in the course of brain cancer regimen if a patient's tumor will shrink, a new study shows.

Researchers at the University of Michigan Comprehensive Cancer Center developed the assessment, which they call a functional diffusion map. They used a magnetic resonance imaging scan that tracks the diffusion, or movement, of water through the brain and mapped the changes in diffusion from the start of therapy to three weeks later. The tumor cells block the flow of water, so as those cells die, water diffusion changes.

In the study of 20 people with malignant brain tumors, the researchers found that any change in the functional diffusion map predicted 10 weeks before traditional techniques if the tumor was responding to the chemotherapy or radiation therapy. This has potential to spare patients from weeks of a grueling treatment regimen that's not working and gives doctors the opportunity to switch patients early on to a therapy that may be more effective.

Results of the study appear the week of March 28 in the early online edition of the Proceedings of the National Academy of Sciences.

Most primary brain tumors have a high mortality rate, with people surviving only 10 months after diagnosis. Typically, patients receive seven weeks of treatment, followed by a traditional MRI scan six weeks after completing therapy to determine if the tumor shrank. If the cancer did not respond to the treatment, a new approach may be tried.

Using diffusion MRI and the functional diffusion map, the U-M researchers were able to predict with 100 percent accuracy after only three weeks of treatment whether the therapy would be effective ?10 weeks before traditional methods would show a response.

"This is an important issue in terms of patient quality of life. Do you want to go through seven weeks of treatment only to find two months
'"/>

Source:University of Michigan Health System


Page: 1 2 3

Related biology news :

1. Duke engineers develop new 3-D cardiac imaging probe
2. Confocal imaging promises early detection of skin cancer
3. Newer imaging techniques may lead to over-treatment
4. Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
5. Microscopic brain imaging in the palm of your hand
6. New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
7. Purdues gold nanorods brighten future for medical imaging
8. PET imaging reveals the immune system at work
9. New technique puts brain-imaging research on its head
10. T-rays: New imaging technology spotlighted by American Chemical Society
11. UCLA imaging study of children with autism finds broken mirror neuron system
Post Your Comments:
(Date:2/5/2015)... Jan. 30, 2015  It is gratifying to see ... potential for genomic science as a means to better ... and treatment.  I was honored to participate in today,s ... medicine program. Since the 1980s my ... genomics—from the first sequenced genome of a free living ...
(Date:1/22/2015)... - Today, FindBiometrics, the leading source of biometrics industry news, interviews ... design. "When we launched FindBiometrics 12 years ago ... , founder and CEO of FindBiometrics. "Now it,s maturing very ... key players on a very broad scale.  We are known ...
(Date:1/22/2015)... Jan. 16, 2015  A man-made form of insulin delivered ... mental capabilities in adults with mild cognitive impairment and ... by researchers at Wake Forest Baptist Medical Center. ... amnesic mild cognitive impairment (MCI) or mild to moderate ...
Breaking Biology News(10 mins):J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3
... of Texas at Austin studying electric fish have gained new ... neurons. , Their finding, published in the Feb. 16 ... and neural disorders like epilepsy in humans. , Dr. Harold ... fish zap each other in dark waters, their neurons store ...
... who undergo surgery for breast cancer followed by ... only be corrected through reconstructive surgery. Researchers at ... with bioengineers at Carnegie Mellon University, have developed ... serve as an artificial tissue filler after surgery ...
... Union speech President Bush said technology is the best way ... of Energy Joint Genome Institute (DOE JGI) is directing the ... that will lead to cheaper and easier to produce biofuels. ... of molecular biology we can generate diagnostic fingerprints, Environmental Genomic ...
Cached Biology News:Mechanism for memory revealed in neurons of electric fish 2Chemotherapy gel may fight breast cancer and reduce breast deformity 2Environmental metagenomics diagnosing extreme environments, tapping opportunities for clean energy 2
(Date:2/26/2015)... Feb. 26, 2015 The healthcare landscape is rapidly ... Frost & Sullivan will host its 20 th ... , March 8 to 10, at the Hilton San Diego ... This event is a platform for global ... discuss industry disruptions and how to succeed in an uncertain ...
(Date:2/26/2015)... Schaumburg, IL (PRWEB) February 26, 2015 ... to its gauging line by expanding its Length Gauge ... and ACANTO gauges. , Specifically, HEIDENHAIN’s pencil ... an improved force specification. Two new 1Vpp, 12mm ... for lower force applications. One is a variant with ...
(Date:2/26/2015)... According to a new market report published ... Crops (Corn, Soybean, Cotton and Others), Synthetic Biology-Enabled Products ... Trends and Forecast, 2013 – 2019,”the global agricultural biotechnology ... and is expected to reach USD 28,694.1 million by ... to 2019. , Demand for food production has ...
(Date:2/26/2015)... OAKS, Calif. , Feb. 26, 2015 ... achieved Gold Partner status in Oracle PartnerNetwork. In attaining ... for its commitment to establish Oracle-related knowledge in delivering ... the challenges of joint customers. Originally developed ... researchers to rapidly zoom in and out of massive ...
Breaking Biology Technology:Embrace the Future of Medical Technologies with Frost & Sullivan 2Embrace the Future of Medical Technologies with Frost & Sullivan 3Accuracy and Versatile Gauging Go Hand in Hand at HEIDENHAIN 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4
... April 8 ImQuest Life Sciences presented their ... their novel small molecule piperazine compound for the ... Therapeutics meeting held in Whistler, British Columbia. The ... lead microtubule inhibitor, IQP-0304. The piperazines demonstrate potent ...
... 8 Micromet, Inc. (Nasdaq: MITI ... for the treatment of cancer, inflammation and autoimmune ... the peer-reviewed Journal of Immunotherapy (1) demonstrating the ... to carcinoembryonic antigen (CEA) and to CD3 on ...
... 7 Pharmatech Oncology, Inc., a Research Management Organization ... companies at the Company Showcase during BIOZONA 2009 - ... Downtown on April 7th in Phoenix, Arizona.Matthew B. Wiener, ... during the first session of the conference. The ...
Cached Biology Technology:ImQuest Presentation at Keystone Symposium Focuses on Advancements in Their Cancer Research and Development Program 2Pre-Clinical Data on CEA-specific BiTE Antibody Published in Journal of Immunotherapy Demonstrate Potent Control of Tumor Growth 2Pre-Clinical Data on CEA-specific BiTE Antibody Published in Journal of Immunotherapy Demonstrate Potent Control of Tumor Growth 3Pre-Clinical Data on CEA-specific BiTE Antibody Published in Journal of Immunotherapy Demonstrate Potent Control of Tumor Growth 4Pharmatech Oncology Selected to Present at Company Showcase at BIOZONA 2
Request Info...
The Proteome Profiler Human Phospho-MAPK Array Kit contains 4 membranes - each spotted in duplicate with 23 different MAPK antibodies....
... Anti-PLCδ-1, clone d1-174 GenBank Accession ... and X-press N-terminal tagged fusion protein corresponding ... Formulation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, ... glycerol to 30% Quality Assurance: routinely evaluated ...
Rat CXCL7/Thymus Chemokine-1 DuoSet Economy Pack, 45 Plate...
Biology Products: