Navigation Links
NYU researchers simulate molecular biological clock

For many years, DNA and proteins have been viewed as the real movers and shakers in genomic studies, with RNA seen as little more than a messenger that shuttles information between the two. But researchers from Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology have discovered that small RNA molecules called microRNAs regulate thousands of human genes--more than one third of the genome's protein-coding regions. In other words, a class of molecule once relegated to the sidelines may be one of the principal players in regulating cellular mechanisms.

"It's exciting to see how many genes are regulated by microRNAs. We now know that this type of gene control is much more widespread than previously appreciated," says Whitehead Member and MIT professor of biology David Bartel. MicroRNAs interrupt a gene's ability to make protein. These tiny, single-stranded pieces of RNA are newcomers to biological research. It wasn't until 2000 that researchers even knew that microRNAs existed in humans. Now, in the January 14 edition of the journal Cell, Benjamin Lewis, a graduate student working jointly with Whitehead's Bartel and MIT associate professor of biology Christopher Burge, provides the first evidence that microRNAs influence a large percentage of life's functions. The team developed a computational method to define the relationship between microRNAs and their target genes. In December 2003, the same group identified 400 genes in the human genome targeted by microRNAs. (Prior to this study, there were no known microRNA targets in any vertebrate.) In their latest paper, taking advantage of the most recent genome-sequencing data, the team has compared human genome data with that of the dog, chicken, mouse, and rat. For each of the microRNAs and protein-coding genes that are common to these five species, the team looked for correspondence between the microRNAs and the protein-coding genes. They discovered that regulation of a third of th
'"/>

Source:


Page: 1 2

Related biology news :

1. Vital step in cellular migration described by UCSD medical researchers
2. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
3. UCSD researchers maintain stem cells without contaminated animal feeder layers
4. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
5. New protein discovered by Hebrew University researchers
6. First real-time view of developing neurons reveals surprises, say Stanford researchers
7. Agilent Technologies releases automated literature search tool for biology researchers
8. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
9. Yale researchers identify molecule for detecting parasitic infection in humans
10. US life expectancy about to decline, researchers say
11. Wisconsin researchers identify sleep gene
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: NYU researchers simulate molecular biological clock

(Date:2/13/2015)... 13, 2015 ACT Genomics Co., Ltd., ... to transform cancer genomic information into precision diagnosis ... has raised US$ 8 million in the its first ... Taipei, Taiwan , ACT Genomics has ... the aim to implement next generation sequencing (NGS) ...
(Date:2/12/2015)... 12, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce ... 62/113114 for DISTRIBUTED METHOD AND SYSTEM TO ... patent further establishes NXT-ID,s position in the emerging "Internet ... the ability for multiple devices to collaborate with one ...
(Date:2/10/2015)... 10, 2015  Alere Inc. (NYSE: ALR), a ... results for the quarter ended December 31, 2014. ... President of Alere said, "We made substantial progress ... the global leader in rapid diagnostics and delivering ... Health divestiture in early January enabled us to ...
Breaking Biology News(10 mins):ACT Genomics Raises $8 Million in its First Private Funding Round 2NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 2NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 3Alere Inc. Announces Fourth Quarter 2014 Results 2Alere Inc. Announces Fourth Quarter 2014 Results 3Alere Inc. Announces Fourth Quarter 2014 Results 4Alere Inc. Announces Fourth Quarter 2014 Results 5Alere Inc. Announces Fourth Quarter 2014 Results 6Alere Inc. Announces Fourth Quarter 2014 Results 7Alere Inc. Announces Fourth Quarter 2014 Results 8Alere Inc. Announces Fourth Quarter 2014 Results 9Alere Inc. Announces Fourth Quarter 2014 Results 10Alere Inc. Announces Fourth Quarter 2014 Results 11Alere Inc. Announces Fourth Quarter 2014 Results 12Alere Inc. Announces Fourth Quarter 2014 Results 13Alere Inc. Announces Fourth Quarter 2014 Results 14Alere Inc. Announces Fourth Quarter 2014 Results 15Alere Inc. Announces Fourth Quarter 2014 Results 16Alere Inc. Announces Fourth Quarter 2014 Results 17Alere Inc. Announces Fourth Quarter 2014 Results 18Alere Inc. Announces Fourth Quarter 2014 Results 19Alere Inc. Announces Fourth Quarter 2014 Results 20Alere Inc. Announces Fourth Quarter 2014 Results 21Alere Inc. Announces Fourth Quarter 2014 Results 22Alere Inc. Announces Fourth Quarter 2014 Results 23Alere Inc. Announces Fourth Quarter 2014 Results 24Alere Inc. Announces Fourth Quarter 2014 Results 25Alere Inc. Announces Fourth Quarter 2014 Results 26Alere Inc. Announces Fourth Quarter 2014 Results 27Alere Inc. Announces Fourth Quarter 2014 Results 28Alere Inc. Announces Fourth Quarter 2014 Results 29Alere Inc. Announces Fourth Quarter 2014 Results 30Alere Inc. Announces Fourth Quarter 2014 Results 31Alere Inc. Announces Fourth Quarter 2014 Results 32Alere Inc. Announces Fourth Quarter 2014 Results 33
... after all when it comes to Alzheimer’s disease. , ... Investigation, a team of scientists from the University of Rochester ... villain when it comes to parsing out damage after a ... in Alzheimer’s disease, protecting the brain and helping get rid ...
... greenhouse gases and increase production at the same time has ... Primary Industries' (DPI) Wollongbar Agricultural Institute. , Trials of agrichar ... soils and the environment - have doubled and, in one ... 10 tonnes per hectare. , Agrichar is a ...
... Why do so many people continue to suffer from life-altering, ... The definitive answer -- and an effective treatment -- has ... morphine derivatives, haven’t worked very well. , A ... pain appears to be an old memory trace that essentially ...
Cached Biology News:Brain inflammation may be friend, not foe, for Alzheimer's patients 2Brain inflammation may be friend, not foe, for Alzheimer's patients 3Brain inflammation may be friend, not foe, for Alzheimer's patients 4Soils offer new hope as carbon sink 2Soils offer new hope as carbon sink 3Old memory traces in brain may trigger chronic pain 2Old memory traces in brain may trigger chronic pain 3
(Date:3/4/2015)... , March 4, 2015  BioClinica®, Inc., ... technology provider, today announced that clinical trial ... convened at its annual European User Conference ... to discuss the use of its eClinical ... eClinical technologies include: the Microsoft Office-Smart OnPoint ...
(Date:3/4/2015)... 2015   ... und Therapie, Strahlendosismanagement und IT-Lösungen für die gesamte ... Philips (NYSE: PHG, AEX: PHIA) gab heute ... (ECR) bekannt, der vom 4. bis 8. März in ... Ständen Nr. 102 and 110 wird das ...
(Date:3/3/2015)... 2015 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") ... for odour control projects in North America , ... . "Bidding activity in 2015 continues to be ... a high volume year for bidding in 2014, we are pleased ... recent orders reflect the organization,s renewed focus on select market segments ...
(Date:3/3/2015)... Ark. (PRWEB) March 03, 2015 ... Systems Inc. to their international sales network. The ... gas dissolution technology to Canada’s Atlantic Provinces, exclusively ... has served as one of Canada’s premiere manufacturing ... in both the municipal water and wastewater markets. ...
Breaking Biology Technology:BioClinica Teams With Pharma To Tackle Clinical Trial Challenges In Europe 2BioClinica Teams With Pharma To Tackle Clinical Trial Challenges In Europe 3Philips stellt integrierte Bildgebungslösungen auf dem Europäischen Röntgenkongress 2015 vor 2Philips stellt integrierte Bildgebungslösungen auf dem Europäischen Röntgenkongress 2015 vor 3Philips stellt integrierte Bildgebungslösungen auf dem Europäischen Röntgenkongress 2015 vor 4Philips stellt integrierte Bildgebungslösungen auf dem Europäischen Röntgenkongress 2015 vor 5Philips stellt integrierte Bildgebungslösungen auf dem Europäischen Röntgenkongress 2015 vor 6BlueInGreen® Continues Canadian Expansion, Partners with Resource Systems Inc. 2
... , AUSTIN, Texas , Feb. 15 ... San Antonio , is presenting at the 5th Annual Stem Cell ... Dr. Johnson will be presenting his most recent data proving the efficacy ... of care technology utilizes the patient,s own cells derived from bone marrow ...
... to the term "power suit," University of California, Berkeley, ... be woven into clothing and textiles. These ... convert into electricity the energy created through mechanical stress, ... lead to wearable ,smart clothes, that can power hand-held ...
... , MINNEAPOLIS , Feb. 12 CoAxia™, ... completion of enrollment in its SENTIS randomized, controlled, pivotal trial ... for ischemic stroke.  The Company plans to complete data collection ... warranted, submit a PMA to the US FDA. , Ischemic ...
Cached Biology Technology:SpineSmith to Present at the 5th Annual Stem Cell Summit 2SpineSmith to Present at the 5th Annual Stem Cell Summit 3New fiber nanogenerators could lead to electric clothing 2CoAxia Announces Completion of Enrollment in Ischemic Stroke Trial 2CoAxia Announces Completion of Enrollment in Ischemic Stroke Trial 3