Navigation Links
NYU biologists identify gene that coordinates two cellular processes

A team of biologists at New York University's Center for Comparative Functional Genomics has uncovered a dual role for the gene mel-28. The gene plays a part in ensuring that chromosomes are divided properly during cell division and it is required for nuclear envelope function. The findings appear in the journal Current Biology.

The team is using functional genomic tools to study the nematode worm Caenorhabditis elegans (C. elegans), the first animal species whose genome was completely sequenced and a model organism to study how embryos develop. The study appearing in Current Biology was performed by NYU's Fabio Piano, an assistant professor, and Anita Fernandez, a post-doctoral researcher, at the Center for Comparative Functional Genomics.

Biologists can draw connections between genes based on systematically accumulated experimental evidence. Network diagrams that illustrate such connections show that most genes fall into highly interconnected groups called modules. These modules are often enriched for genes that share the same role. In order to determine the functions of genes whose role is unknown, researchers examine genes in the same module whose function has already been discovered. This approach has proven useful for learning about the roles of unknown genes.

Unlike most genes in the network, mel-28 had connections to two distinct modules. Piano and Fernandez tested the idea that mel-28 plays important roles in both chromosome segregation and nuclear envelope function. Part of this undertaking included examining the protein MEL-28, which the gene mel-28 encodes.

By fusing mel-28 to a gene-encoding GFP, a fluorescent marker, and expressing this fusion in early embryos, they visualized the movement of MEL-28 during cell division in living embryos. Consistent with the idea that MEL-28 had function in chromosome segregation and the nuclear envelope, the MEL-28-GFP fusion was observed to shuttle between the nuclear periphe
'"/>

Source:New York University


Page: 1 2

Related biology news :

1. Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
2. GeneNotes - A novel information management software for biologists
3. NYU biologists map out early stages of embryo formation
4. FSU biologists describe key role of signal-transcribing gene during cell cycle
5. High-tech tags on marine animals yield valuable data for biologists and oceanographers
6. UCSD biologists find new evidence for one-way evolution
7. UC San Diego biologists solve plant growth hormone enigma
8. FSU biologists uncover mechanisms that shape cells for better or worse
9. MIT biologists solve vitamin puzzle
10. Yale biologists trick viruses into extinction
11. Brown cancer biologists identify major player in cell growth
Post Your Comments:
(Date:8/1/2014)... at The Scripps Research Institute (TSRI) have identified a ... in brown fat cells. , The study, which ... the Proceedings of the National Academy of Sciences ... fat thermogenesis," which is of great interest to medical ... also protect against diabetes. , "This finding offers new ...
(Date:7/31/2014)... In the United States, natural-gas production from shale ... since 2007. Yet scientists still do not fully ... according to a report in the journal ... As gas extraction continues to vastly outpace scientific ... various organizations and institutions, including Princeton University, concluded ...
(Date:7/31/2014)... Fla. --- By tracing nearly 3,000 genes to ... University of Florida scientists have created an extensive ... use large-scale, next-generation DNA sequencing. , Among ... closely related to small moths than to large ... butterflies evolved. The study also found that some ...
Breaking Biology News(10 mins):Scripps Research Institute scientists find new calorie-burning switch in brown fat 2Scripps Research Institute scientists find new calorie-burning switch in brown fat 3'Fracking' in the dark: Biological fallout of shale-gas production still largely unknown 2'Fracking' in the dark: Biological fallout of shale-gas production still largely unknown 3UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3
... Knut Stamnes, Professor and Department Director of Physics ... has been awarded a NASA grant for work ... satellite. His proposal to "use and further develop ... coupled atmosphere-surface systems" is funded as part of ...
... Senior Design team at Stevens Institute of Technology is ... arise during thoracic surgeries. Five undergraduate Biomedical Engineering students ... of existing catheter design and introduces a potentially profitable ... the efforts of the Stevens Innovative Fluid Extraction System ...
... revealing how age-old irrigation techniques may have boosted the ... an estimated 200 million people today. ... kingdom that was located in present-day Sudan, provides details ... disease across populations in ancient times, and how human ...
Cached Biology News:Dr. Knut Stamnes at Stevens receives NASA grant for environmental monitoring 2Dr. Knut Stamnes at Stevens receives NASA grant for environmental monitoring 3Stevens thoracic catheter senior design team takes 1st place at regional ISPE competition 2Stevens thoracic catheter senior design team takes 1st place at regional ISPE competition 3Mummies tell history of a 'modern' plague 2Mummies tell history of a 'modern' plague 3
(Date:8/1/2014)... Corporation (NYSE: CBM ) reports results for the ... , Second quarter sales increased 59% to $98.0 ... , Second quarter EBITDA increased 86% to $21.2 million ... (see table at the end of this release). , ... foreign currency, to between 13% and 16% over 2013, and ...
(Date:7/31/2014)... Dallas, Texas (PRWEB) August 01, 2014 ... Global and China Polyurethane Resin Industry” is ... Polyurethane Resin market. The report introduces Polyurethane ... application, and industry chain structure and industry ... analysis, including China’s domestic market as well ...
(Date:7/31/2014)... the British mathematician (1912-1954), is famous for a number ... century. In 1936 he published a paper, which laid ... concept of a computer algorithm. He next played a ... machines which cracked the German military codes, enabling the ... And in the late 1940,s he turned his attention ...
(Date:7/31/2014)... , July 31, 2014 The ... today with $25,000 to fund a translational research ... in 2011, the gift was presented at the ... Annual Meeting in Colorado Springs, CO. ... in neurointerventional approaches to neurovascular conditions, SNIS formed ...
Breaking Biology Technology:Cambrex Reports Second Quarter 2014 Financial Results 2Cambrex Reports Second Quarter 2014 Financial Results 3Cambrex Reports Second Quarter 2014 Financial Results 4Cambrex Reports Second Quarter 2014 Financial Results 5Cambrex Reports Second Quarter 2014 Financial Results 6Cambrex Reports Second Quarter 2014 Financial Results 7Cambrex Reports Second Quarter 2014 Financial Results 8Cambrex Reports Second Quarter 2014 Financial Results 9Cambrex Reports Second Quarter 2014 Financial Results 10Cambrex Reports Second Quarter 2014 Financial Results 11Cambrex Reports Second Quarter 2014 Financial Results 12Cambrex Reports Second Quarter 2014 Financial Results 13Cambrex Reports Second Quarter 2014 Financial Results 14Cambrex Reports Second Quarter 2014 Financial Results 15Cambrex Reports Second Quarter 2014 Financial Results 16Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 2Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 3Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 4A mathematical theory proposed by Alan Turing in 1952 can explain the formation of fingers 2A mathematical theory proposed by Alan Turing in 1952 can explain the formation of fingers 3SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 2SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 3
... individuals are invited to enter the 35th ... benefits coming from research and engineering of new ... Products Awards are given in four major categories: ... (500-999 employees); medium companies (50-499 employees); and small ...
... gave about $400,000 worth of software to ... youth and their families. Rob Busch, enterprise sales manager ... at the non-profit's Synergy School in Milwaukee for the ... to upgrade Lad Lakes network and software infrastructure, including ...
... Wis. If Wisconsin is to attract the ... it first has to focus on its own environment, ... Biotechnology and Medical-Devices Association. , ,Part of building the ... large corporations, said WBMA President and EraGen CEO Irene ...
Cached Biology Technology:Panel stresses drawing outside biotech firms to state 2
AVOID FREEZE/THAW CYCLES. Recognizes the ~32 kDa DNase IIα chain and the ~40 kDa proenzyme. DNase II causes both DNA condensation and DNA fragmentation. ...
BD BioCoat Vented Caps for 175 cm2 Flasks...
...
I-Ab MHC Class II...
Biology Products: