Navigation Links
Microscopic brain imaging in the palm of your hand

New portable device captures pictures beneath the living brain's surfaceResearchers at Stanford University have demonstrated a promising, minimally invasive optical technique that can capture micron-scale images from deep in the brains of live subjects. The method, called two-photon microendoscopy, combines a pair of powerful optical and mechanical techniques into one device that fits in the palm of the hand. The results appear in the September 1, 2005 issue of Optics Letters, a journal published by the Optical Society of America.

Researchers want to image individual cells inside living subjects because it will give them insight into how cellular behavior gives rise to the properties of organisms as a whole. For instance, the nerve cells of the hippocampus region of the brain give rise to important mental processes such as learning and memory.

Imaging living cells below the surface has been difficult to accomplish using conventional techniques. Electron microscopy can't be used on living tissue, and optical (light) microscopy can't penetrate very deeply into tissue because light scatters as it travels through tissue near the surface. Thus traditionally microscopic images of the living brain have only been made near the surface. Yet researchers would like to know more about certain deep-tissue areas of the brain, which are critical to understanding Alzheimer's and Parkinson's disease, for example.

Scientists often use some form of fluorescence microscopy to image tissue. In conventional "one-photon" fluorescence imaging, the scientist injects a dye into tissue and then shines a bright light. The tissue fluoresces, or radiates, light of a different color in response. However, a problem with one-photon fluorescence is that the deep tissue causes the photons to ricochet, or scatter, as they return to the detector. The result is a background haze in the images, almost like viewing the sample through a cloud.

It's possible to get rid of bac
'"/>

Source:American Institute of Physics


Page: 1 2 3

Related biology news :

1. Microscopic scaffolding offers a simple solution to treating skin injuries
2. Microscopic passengers to hitch ride on space shuttle
3. Controversial drug shown to act on brain protein to cut alcohol use
4. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
5. Mouse brain tumors mimic those in human genetic disorder
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. First atlas of key brain genes could speed research on cancer, neurological diseases
8. NYU study reveals how brains immune system fights viral encephalitis
9. Stem cells from brain transformed to produce insulin at Stanford
10. Birds brains reveal source of songs
11. Loves all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Microscopic brain imaging the palm your hand

(Date:10/30/2014)... Oct. 29, 2014  Securus Technologies, a ... technology solutions for public safety, investigation, corrections ... deployed exciting enhancements to its THREADS™ product, ... provide actionable intelligence and focused leads for ... drive technological innovation through identifying and delivering ...
(Date:10/29/2014)... a consequence of chemotherapy will benefit from a major ... that prevents hair loss. , The research is being ... cooling manufacturing company, Paxman Coolers, of Fenay Bridge, Huddersfield, ... of Huddersfield. , The research will be led by ... the pharmacology of cancer treatment, which he will use ...
(Date:10/29/2014)... New research presented at the Society for ... TX showed for the first time that it ... using a readily available nutritional supplement, AHCC. ... Judith A. Smith, Pharm.D., associate professor in the ... The University of Texas Health Science Center at ...
Breaking Biology News(10 mins):Securus Technologies Adds Advanced Features to Its Industry-Leading Investigative Analytics Product 2New technology on the way to aid cancer suffers who lose their hair after chemotherapy 2HPV infections in women eradicated by AHCC, Japanese mushroom extract 2
... professor of biology at Kansas State University, is interested in ... forms. , Take the fruit fly and the beetle, for ... same segmented body plan consisting of head, thorax and abdomen, ... in the embryo. Fruit flies make segments all at once; ...
... IQ are distinguished by how fast the thinking part ... up, researchers at the National Institutes of Health's (NIH) ... , Magnetic resonance imaging (MRI) scans showed that their ... childhood, reaching its peak later than in their peers ...
... forthcoming issue of The American Naturalist attempts to explain ... many diving beetle populations. Their findings have important implications ... costs and benefits of multiple matings differ for males ... arms race (involving physical structures, behaviors, chemicals, etc.) for ...
Cached Biology News:Scaled-down genome may power up E. coli's ability in lab, industry 2Cortex matures faster in youth with highest IQ 2
(Date:10/31/2014)... (PRWEB) October 30, 2014 The ... Product Development’s decades-long heritage in successful medical device ... context for what it takes to successfully innovate ... As part of a two-hour on-site class, Insight ... school of business, McCormick School of Engineering, medical ...
(Date:10/31/2014)... The report "Dairy Alternative (Beverage) Market by Type ... Channel (Supermarket, Health Store, Pharmacy, Convenience Store) & ... defines and segments the dairy alternative beverage market ... volume for plant-based dairy alternative beverages. , The ... by 2018 with the Asia-Pacific region as the ...
(Date:10/31/2014)... ATLANTA , Oct. 31, 2014  Atlanta-based ... research efforts accompanying the onset of Ebola by ... options. Scientists at Georgia Tech,s Center for Computational ... and algorithms to find alternative uses for existing ... be able to aid the bout against Ebola. ...
(Date:10/30/2014)... 2014 Deep Research Report on ... professional and in-depth research report on the China ... information, including its definition, classification, application, and industry ... research covers the international market analysis, including China’s ... covering macroeconomic environment & economic situation analysis. The ...
Breaking Biology Technology:Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 3Dairy Alternative Beverage Market Projected to Reach $14 Billion by 2018 - Report by MarketsandMarkets 2Dairy Alternative Beverage Market Projected to Reach $14 Billion by 2018 - Report by MarketsandMarkets 3Dairy Alternative Beverage Market Projected to Reach $14 Billion by 2018 - Report by MarketsandMarkets 4Atlanta-Based Intellimedix May Help Solve Ebola With Computer Algorithms 2Naltrexone HCL Market & Nalbuphine HCL Industry Analysis for Global, China Regions Now at DeepResearchReports.com 2Naltrexone HCL Market & Nalbuphine HCL Industry Analysis for Global, China Regions Now at DeepResearchReports.com 3
... Nov. 9 /PRNewswire-Asia-FirstCall/ -- Yongye International, Inc.,(Nasdaq: YONG ... distributor of Shengmingsu brand plant and animal nutrient products ... it will conduct a,conference call at 10:00 a.m. Eastern ... to discuss results for the quarter ended September 30, ...
... (NYSE Amex: CVM) announced today that Dr. ... Northeastern Ohio Universities College of Medicine and Pharmacy, reported ... Cleveland Clinic and CEL-SCI on CEL-SCI,s LEAPS vaccine technology. ... Vaccine: "All Things Considered" Conference in Crystal City, Virginia. ...
... Nov. 5, 2009 Complete Genomics, a third-generation human ... in the journal Science describing its proprietary ... three complete human genomes. The consumables cost for these ... ranged from $8,005 for 87x coverage to $1,726 for ...
Cached Biology Technology:Yongye International Announces Conference Call to Discuss Third Quarter 2009 Results 2Yongye International Announces Conference Call to Discuss Third Quarter 2009 Results 3CEL-SCI Collaborators Present Data Suggesting That LEAPS Technology Has Ability to Modify Immune Response 2CEL-SCI Collaborators Present Data Suggesting That LEAPS Technology Has Ability to Modify Immune Response 3Complete Genomics publishes in Science on low-cost sequencing of 3 human genomes 2