Navigation Links
Math model predicts cancer behavior

Vito Quaranta clicks on a small black dot on his computer screen. The dot ?which represents about a thousand cancer cells ?begins to "grow," morphing into a mass with finger-like projections that looks like an invasive tumor.

The Vanderbilt professor of cancer biology envisions a future when computer simulations like this will be used to predict a tumor's clinical progression and formulate individualized treatment plans. For the last two years, he has headed a major effort to develop the kind of mathematical model for cancer invasion powerful enough for this purpose. The result was published as an entirely theoretical paper in the journal Cell and, if he is right, it represents a "sea change" in how biology is done.

The new approach is not so different from forecasting the weather.

"Today we can know pretty well that for the next few days we're going to expect good weather or that there's a storm on the way," Quaranta said. "That's the kind of predictive power we want to generate with our model for cancer invasion."

Quaranta and colleagues at Vanderbilt University and the University of Dundee in Scotland developed a computational model for cancer invasion and described the model in the Dec. 1 issue of Cell. The model ?a series of mathematical equations that drive computer simulations of tumor growth ?suggests that the microenvironment around tumor cells determines the tumor's ultimate cellular makeup and invasive potential.

The investigators have focused on the events of invasion and metastasis (movement of a tumor to distant sites), Quaranta said, because these events mark "the critical transition of a tumor that in the end will be lethal for the patient." A tumor that does not penetrate the surrounding tissue can often be surgically removed with curative success.

"When a patient comes in with a tumor, we'd like to understand for that particular tumor, what are the chances that metastasis is going to occur," Quara
'"/>

Source:Vanderbilt University Medical Center


Page: 1 2 3 4

Related biology news :

1. Scientists identify new model Of NK cell development
2. Genrate: a generative model that finds and scores new genes and exons in genomic microarray data
3. Molecular models advance the fight against malaria
4. NYU and MSKCC research provides model for understanding chemically induced cancer initiation
5. Genetic therapy reverses nervous system damage in animal model of inherited human disease
6. Disease progression model of pancreatic cancer developed by Penn researchers
7. A new way to share models of biological systems
8. Understanding biases in epidemic models important when making public health predictions
9. Climate model links higher temperatures to prehistoric extinction
10. Gene therapy advance treats hemophilia in mouse models
11. Targeting a key enzyme with gene therapy reversed course of Alzheimers disease in mouse models
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Math model predicts cancer behavior

(Date:8/5/2015)... New York , August 5, 2015 ... market report titled "Facial Recognition Market - Global Industry ... 2022", the global market for facial recognition is forecast ... is driven by increased demand for surveillance systems by ... the rising number of crimes and terrorist activities across ...
(Date:8/4/2015)... Aug. 04, 2015 ... has announced the addition of the ... and Service), Sub-Segment (Computer Forensics, Network Forensics, ... Types, Service, Vertical and Region - Global ... offering. By Component (Hardware, Software, ...
(Date:8/3/2015)... Synaptics, Inc. (Nasdaq: SYNA ), the ... members of the executive management team will present to ... Leadership Forum on Tuesday, August 11, 2015 at 1:00 ... the Sonnenalp Resort in Vail, CO. ... information. An audio webcast of the event will be ...
Breaking Biology News(10 mins):Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2
... In unprecedented new research, scientists at Rice University ... time to both predict theoretically and verify experimentally ... , The interdisciplinary research appears this week in ... National Academy of Sciences. , "Researchers have successfully ...
... computerized system to easilymonitor the levels of glucose in ... published today in the open access journal BMC MedicalInformatics ... assists in the monitoring of glucose levels incritically ill ... than the paper-based method currently used in manyintensive care ...
... protein called vasostatin may prove a promising new way of ... Gut. , Pancreatic cancer is the fifth leading cause of ... to treat. Only 3% of affected patients are still alive ... static for the past three decades. , Currently, the only ...
Cached Biology News:Free-energy theory borne out in large-scale protein folding 2Free-energy theory borne out in large-scale protein folding 3Jefferson researchers find nanoparticle shows promise in reducing radiation side effects 2
(Date:9/1/2015)... , September 2, 2015 ... primär auf die Forschung und Entwicklung neuartiger ... Allergien, chronisch-entzündliche Darmerkrankungen und Reizdarm konzentriert, erhält ... Zusage, dass sein neues Medikament patentiert wird. ... das Allergien bei Kindern verhindert und Entzündungen ...
(Date:9/1/2015)... N.J. , Sept. 1, 2015  ContraVir Pharmaceuticals, ... on the development and commercialization of targeted antiviral therapies, ... & Renshaw 17 th Annual Global Investment Conference ... place September 8-10, 2015 at The St. Regis Hotel ... James Sapirstein , Chief Executive Officer, ...
(Date:9/1/2015)... Eau Claire, WI (PRWEB) , ... September 01, 2015 , ... ... 2015), Alexi Venice expertly transports the reader to a not-so-distant future faced with an ... McCallan, a beautiful professional who overcomes personal tragedy to enter the world of counterterrorism, ...
(Date:9/1/2015)... 2015 The Dohmen Company today announced ... MBA as Chief Science Officer (CSO) of Dohmen ... role, Dr. Floyd will lead Dohmen,s growing regulatory ... pre-commercial and post approval outsourced services in quality, ... Dr. Floyd brings decades of experience leading global ...
Breaking Biology Technology:Das Patent von Swecure zur Verhinderung von Allergien bei Kindern wird in den USA zugelassen 2ContraVir to Present at Rodman & Renshaw 17th Annual Global Investment Conference 2Alexi Venice’s Debut Novel Takes on the Human Testing of a Vaccine for Ebola and Revenge by an Anti-Big Pharma Terrorist Group in ‘Ebola Vaccine Wars' 2Alexi Venice’s Debut Novel Takes on the Human Testing of a Vaccine for Ebola and Revenge by an Anti-Big Pharma Terrorist Group in ‘Ebola Vaccine Wars' 3Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 2Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 3
... YORK, Feb. 17 The following is from Betsy ... "Ruin Your Health With the Obama Stimulus Plan."I am ... a correction. Mr. Olbermann charges that I, Betsy McCaughey, ... industry, the biotech industry, the Hudson Institute, or Cantel ...
... Mass., Feb. 17 Idenix Pharmaceuticals, Inc. (Nasdaq: ... development of drugs for the treatment of human viral and ... fourth quarter and year ended December 31, 2008. At December ... $46.1 million. Business Highlights , , ...
... ... DE (Vocus) February 17, 2009 -- DuPont today announced that ... are in compliance with the Excellence Through StewardshipSM (ETS) ... confirms that the company uses the tools of biotechnology ethically and ...
Cached Biology Technology:Idenix Pharmaceuticals Reports Fourth Quarter and Year End Financial Results 2Idenix Pharmaceuticals Reports Fourth Quarter and Year End Financial Results 3Idenix Pharmaceuticals Reports Fourth Quarter and Year End Financial Results 4Idenix Pharmaceuticals Reports Fourth Quarter and Year End Financial Results 5Idenix Pharmaceuticals Reports Fourth Quarter and Year End Financial Results 6Idenix Pharmaceuticals Reports Fourth Quarter and Year End Financial Results 7DuPont Biotech Stewardship Program Gains External Certification 2DuPont Biotech Stewardship Program Gains External Certification 3
Polyclonal Antibody to SHPRH...
Rabbit polyclonal to TetR ( Abpromise for all tested applications). Antigen: Synthetic peptide: AQKLGVEQPTLYWHVKNKR, corresponding to amino acids 31 - 49 of TetR...
Biotin anti-mouse Ly-49C/F/I/H...
Peptide-affinity Purified Polyclonal Antibody to Retinoic Acid-Induced 3 (RAI3/RAIG1)...
Biology Products: