Navigation Links
Living view in animals shows how cells decide to make proteins

ly in their natural environment versus an artificially created environment such as a laboratory tissue culture," Garcia-Blanco said. "The complexity of alternative splicing necessitates its visualization as the decisions are occurring, because taking a cell out of its context shows only its current status and not how it arrived at that place."

For instance, the splicing process can change even from day to day as an animal develops, he said, adding that extracting cells and watching them in a culture cannot convey all of these transient changes.

Moreover, different cell types within the brain or other organs can exhibit different splicing decisions, Garcia-Blanco said. For example, neurons reside next to glial cells in the brain, yet they express different proteins in different amounts, and detecting such differences in cell cultures can be exceedingly difficult, he said.

"This is a powerful tool to apply to mouse genetics to learn when and where in the animals' bodies alternative splicing decisions are made and, eventually, to learn what factors are critical in making these decisions," Garcia-Blanco said.

"Given the importance of alternative splicing in health and disease," he added, "this anatomic mapping of splicing decisions may give us considerable insight into the many human diseases associated with improper regulation of splicing."
'"/>

Source:Duke University Medical Center


Page: 1 2 3

Related biology news :

1. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
2. Living with salt
3. Living anti-HIV gel shows early promise
4. Living taste cells produced outside the body
5. Living laboratory found on shoreline statues
6. Study: Living coral reefs provide better protection from tsunami waves
7. Living with water scarcity -- world must act now
8. Plants, animals share molecular growth mechanisms
9. Elephants imitate truck noises, other animals
10. Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
11. Gene therapy for Parkinsons disease moves forward in animals
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Living view animals shows how cells decide make proteins

(Date:4/23/2014)... chronic inflammatory disorders among people of lower socioeconomic status ... to the microbes that thrive in rural environments, according ... in the journal Clinical & Experimental Immunology , ... less access to green spaces may be more apt ... system dysfunction. , When our immune systems are working ...
(Date:4/23/2014)... diagnosed with Huntington,s disease, most in their mid-thirties ... physical, and behavioral decline within two decades. "Mutant" ... the genetic disease, have been the primary focus ... according to new research from Prof. Gerardo Lederkremer ... Department of Cell Research and Immunology, in collaboration ...
(Date:4/23/2014)... NY. (Apr. 23, 2014) People who have had ... to restore neurological function. However, a study conducted in ... of Cell Transplantation , but is currently freely ... http://www.ingentaconnect.com/content/cog/ct/pre-prints/content-ct1168Chen , has found that when one group of ... (PBSCs) injected directly into the brain and a similar ...
Breaking Biology News(10 mins):Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3On the defensive 2On the defensive 3Autologous stem cell therapy improves motor function in chronic stroke victims 2
... Society by Joaquin Marro is a wide-ranging and accessible ... strategies and concepts that help us understand the boundaries ... and biology on the other. From cooperation ... addresses many of the topics belonging to the broad ...
... Even though multiple sclerosis is largely caused by genetic ... is lower than previously assumed. This is the conclusion ... scientific journal Brain . In the present ... risks for multiple sclerosis (MS) by using population registers ...
... nanotechnology we,ve gotten electronic skin, or e-skin, and electronic ... of electronic whiskers. Researchers with Berkeley Lab and the ... from composite films of carbon nanotubes and silver nanoparticles ... rats. These new e-whiskers respond to pressure as slight ...
Cached Biology News:Modest familial risks for multiple sclerosis 2E-whiskers 2
(Date:1/15/2014)... A study has been launched to test whether technology ... help to tackle the problem of obesity.  This unique healthcare ... based in Stowmarket) and academics at University Campus Suffolk is ... which is inspired by equipment used to collect data about ...
(Date:1/15/2014)... Arizona (PRWEB) January 15, 2014 2013 ... for Scottsdale’s Brain State Technologies®. They saw continued independent ... Medical Center who were awarded a $1 million grant ... published in “Brain and Behavior” a peer reviewed journal, ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... Texas , Jan. 14, 2014 The ... and research medicinal plants and therapeutic derivatives thereof ... health professionals, and researchers about the challenges of ... http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The Society ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8
... SAN FRANCISCO, Oct. 12 In a study presented ... Chemotherapy (ICAAC), researchers used a mobile, automated UV device ... (VA) Medical Center in Ohio and analyzed its ability ... device, known as Tru-D, uses reflected UVC germicidal energy ...
... Oct. 12 ImaginAb, Inc. and BZL Biologics, LLC ... for the field of diagnostic imaging for PET and ... agreement with BZL as we believe that huJ591 will ... the diagnosis and management of prostate cancer. BZL,s technology ...
... in Europe,s healthcare industry were recognised at Frost ... held in London on 8th October 2009. 17 ... prestigious event. , (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ) ... including drug discovery technologies, healthcare and life sciences ...
Cached Biology Technology:Researchers Present 'a Novel, Automated, Efficient Environmental Disinfection Technology that Significantly Reduces C. difficile, VRE and MRSA Contamination' 2Researchers Present 'a Novel, Automated, Efficient Environmental Disinfection Technology that Significantly Reduces C. difficile, VRE and MRSA Contamination' 3ImaginAb, Inc. and BZL Biologics, LLC Conclude Licensing Agreement for Imaging Rights to huJ591/Prostate-Specific Membrane Antigen (PSMA) 2Frost & Sullivan's 2009 Excellence in Healthcare Awards Banquet Honours Industry's Top Performers 2Frost & Sullivan's 2009 Excellence in Healthcare Awards Banquet Honours Industry's Top Performers 3
ERalpha (Ser 104/106)...
... Alkaline Phosphatase, Calf Intestinal (CIAP), catalyzes the ... and ribo- and deoxyribonucleoside triphosphates. This enzyme ... of linearized cloning vector DNA by removing ... also be used for the dephosphorylation of ...
Mouse CXCR3 Allophycocyanin MAb (Clone 220803)...
Homo sapiens palladin...
Biology Products: