Navigation Links
Heat-shock protein vaccine reduces alveolar bone loss

Heat-shock protein (HSP) can be utilized as a vaccine to cross-protect against multiple pathogenic species. Investigators from Pusan National University (South Korea) today presented the findings of a study they performed to evaluate the bacterium Porphyromonas gingivalis heat-shock protein (HSP) 60 as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss.Recombinant P. gingivalis HSP60 was produced and purified from P. gingivalis GroEL gene. Rats were immunized with P. gingivalis HSP60, and experimental alveolar bone loss was induced by infection with multiple periodontopathogenic bacteria.

There was a very strong inverse relationship between post-immune anti-P. gingivalis HSP immunoglobulin G levels and the amount of alveolar bone loss induced by either P. gingivalis or multiple bacterial infection (p = 0.007). Analysis of data from polymerase chain-reaction indicated that the vaccine successfully eradicated the multiple pathogenic species.

The researchers concluded that P. gingivalis HSP60 could potentially be developed as a vaccine to inhibit periodontal disease induced by multiple pathogenic bacteria.


'"/>

Source:International & American Association for Dental Research


Page: 1

Related biology news :

1. New, automated tool successfully classifies and relates proteins in unprecedented way
2. New binding target for oncogenic viral protein
3. Controversial drug shown to act on brain protein to cut alcohol use
4. Timing is everything: First step in protein building revealed
5. UWs Rosetta software to unlock secrets of many human proteins
6. Researchers find how protein allows insects to detect and respond to pheromones
7. Signaling protein builds bigger, better bones in mice
8. Ancient olfaction protein is shared by many bugs, offering new pest control target
9. Automatic extraction of gene/protein biological functions from biomedical text
10. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/6/2017)... Forecasts by Product Type (EAC), Biometrics, Card-Based ... & Logistics, Government & Public Sector, Utilities / Energy ... Nuclear Power), Industrial, Retail, Business Organisation (BFSI), Hospitality & ... for a definitive report on the $27.9bn Access Control ... ...
(Date:4/5/2017)... 2017 KEY FINDINGS The global ... a CAGR of 25.76% during the forecast period of ... factor for the growth of the stem cell market. ... MARKET INSIGHTS The global stem cell market is ... geography. The stem cell market of the product is ...
(Date:3/30/2017)... -- On April 6-7, 2017, Sequencing.com will host the world,s ... at Microsoft,s headquarters in Redmond, Washington ... health and wellness apps that provide a unique, personalized ... is the first hackathon for personal genomics and the ... the genomics, tech and health industries are sending teams ...
Breaking Biology News(10 mins):
(Date:9/14/2017)... ... 2017 , ... One of the world’s largest World Marrow Donor Day events ... that day, the GenCure Marrow Donor Program will be signing up potential donors for ... San Antonio. , The registration tables will be staffed by employees from all the ...
(Date:9/12/2017)... ... 2017 , ... PhysIQ, a Chicago-based company that provides a ... and clinical trial support, earned DPharm Idol 2017 honors at the 7th annual ... in 2005, PhysIQ leverages artificial intelligence (AI) to empower digital health. The company ...
(Date:9/12/2017)... , ... September 12, 2017 , ... ... extremely pleased to announce that Jeremy Nicholson, Head of the Department of Surgery ... will deliver the 2018 Wallace H. Coulter Lecture. His presentation, “Analytical Science ...
(Date:9/12/2017)... ... September 11, 2017 , ... An August 30th article on Daily ... idea that only aging and overweight patients suffer from enlarged veins (genetics are also ... cosmetic concern. , The Washington State clinic Northwest Vein & Aesthetic Center notes ...
Breaking Biology Technology: