Navigation Links
Heat-shock protein vaccine reduces alveolar bone loss

Heat-shock protein (HSP) can be utilized as a vaccine to cross-protect against multiple pathogenic species. Investigators from Pusan National University (South Korea) today presented the findings of a study they performed to evaluate the bacterium Porphyromonas gingivalis heat-shock protein (HSP) 60 as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss.Recombinant P. gingivalis HSP60 was produced and purified from P. gingivalis GroEL gene. Rats were immunized with P. gingivalis HSP60, and experimental alveolar bone loss was induced by infection with multiple periodontopathogenic bacteria.

There was a very strong inverse relationship between post-immune anti-P. gingivalis HSP immunoglobulin G levels and the amount of alveolar bone loss induced by either P. gingivalis or multiple bacterial infection (p = 0.007). Analysis of data from polymerase chain-reaction indicated that the vaccine successfully eradicated the multiple pathogenic species.

The researchers concluded that P. gingivalis HSP60 could potentially be developed as a vaccine to inhibit periodontal disease induced by multiple pathogenic bacteria.


'"/>

Source:International & American Association for Dental Research


Page: 1

Related biology news :

1. New, automated tool successfully classifies and relates proteins in unprecedented way
2. New binding target for oncogenic viral protein
3. Controversial drug shown to act on brain protein to cut alcohol use
4. Timing is everything: First step in protein building revealed
5. UWs Rosetta software to unlock secrets of many human proteins
6. Researchers find how protein allows insects to detect and respond to pheromones
7. Signaling protein builds bigger, better bones in mice
8. Ancient olfaction protein is shared by many bugs, offering new pest control target
9. Automatic extraction of gene/protein biological functions from biomedical text
10. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Heat shock protein vaccine reduces alveolar bone loss

(Date:8/28/2014)... support of peer groups and clinicians is critical ... to recent University of Georgia research. , A ... County area determined that role models for successful ... of infants. , "Mothers who received that support ... said study co-author Alex Anderson, an associate professor ...
(Date:8/28/2014)... 2014  Privacy Advocate and Senior Staff Attorney at ... joins the lineup of biometric and mobile commerce experts ... Executive Summit in Tampa, Florida ... speakers include Steven Rahman, Director, Technology and Strategy at Samsung, ... The theme of this year,s event is Mobility at ...
(Date:8/28/2014)... MARC (Maximizing Access to Research Careers) Program has ... College of Sports Medicine,s Conference on Integrative Physiology ... Florida. These awards are meant to promote ... from underrepresented groups into the mainstream of the ... of young scientists at the American College of ...
Breaking Biology News(10 mins):Breastfeeding study shows need for effective peer counseling programs 2Biometrics UnPlugged Welcomes the Electronic Frontier Foundation's Jennifer Lynch to the Mobility at the Crossroads of Commerce and Privacy Summit 2
... and Education (CARE) Unit ( www.bumc.bu.edu/CARE ) in the ... awarded a $1,886,087 renewal grant from the National ... to become sophisticated implementers of substance use screening, assessment ... renewal from the national institute on Drug Abuse to ...
... Ebersberg, Germany, February 14, 2011 - Eurofins MWG Operon, ... to 5 different non-cloned genomic DNA libraries for sequencing with ... are a combination of shotgun and long paired end (LPE) ... kb and up to 40 kb). After sequencing, the resulting ...
... Two scientific publications report on improved methods for ... chocolate. The research, sponsored by The Hershey Center ... at The Hershey Company and other scientific laboratories. ... separated cocoa flavanol antioxidants on a large scale. ...
Cached Biology News:Hershey scientists improve methods for analysis of healthful cocoa compounds 2
(Date:8/28/2014)... LAFAYETTE, Ind. A new research platform ... properties of tiny structures undergoing stress and ... to improve designs for microelectronics and batteries., ... reveals information about how heating and the ... mechanical properties. Researchers have discussed the merits ...
(Date:8/28/2014)... 28, 2014  Next month, executives from clinical trial marketing ... events beginning with Patient-Centered Clinical Trials 2014 , to ... Boston , September 4-5. Patient recruitment experts Bonnie ... Fleishman will share insights on the benefits of employing ... tactics – from media to mobile apps – can be ...
(Date:8/28/2014)... Fla. Exciting new work by a Florida State ... system that can take your temperature, emit white light, ... And, the molecule looks like a butterfly. , Biwu ... Biomedical Engineering in the FAMU-FSU College of Engineering, created ... but has continued to discover that his creation has ...
(Date:8/28/2014)... MA (PRWEB) August 28, 2014 ... wholesale construction materials, selected SoundConnect to ... their cloud based audio and web conferencing platform ... to support PrimeSource’s employees’ needs. SoundConnect delivers ... , PrimeSource Building Products will be utilizing ...
Breaking Biology Technology:New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3BBK Worldwide Leads Sessions at Key September Events 2Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 2PrimeSource Chooses SoundConnect as Collaboration Provider 2
... 100 companies for innovative technologySALT LAKE CITY, May 4 ... through the development of molecular diagnostic technologies, was selected ... Award Ceremony. The award recognizes significant innovations and the ... Stoel Rives, LLP presented the award to Axial Biotech ...
... LLC, a Boston-based life science investment bank, is pleased ... the firm as senior advisor. In this role, ... and client-related activities including private equity placements and merger ... medical device transactions. "We are thrilled to welcome ...
... today that the company has recently closed a $8.5 ... Fifth Third Bank. This new credit facility consists of ... revolving working capital line of credit."Our ability to close ... banking environment speaks to the strength of the company,s ...
Cached Biology Technology:Axial Biotech Wins 2009 Innovation Award for Biotechnology 2Venture Capital Veteran John Brooks Joins Life Science Investment Bank Johnston Blakely & Company 2Pulse Systems Announces New $8.5 Million Credit Facility 2
This issue concentrated on the purification of proteins for specific purposes (i.e. large-scale purification, purification for therapeutic use, etc.)...
... (1997) • Contains short but ... & molecular biology, arranged under ... give details of biochemical substances ... they are involved and define ...
Edited by D.M. Gersten (1996) Provides comprehensive descriptions of the techniques available for analytical gel electrophoresis of proteins and offers clear step-by-step protocols for all of the m...
The Protein Kinase Factsbooks (2 Volume Set)...
Biology Products: