Navigation Links
Gene discovery opens door to tackling disease

Western Australian researchers have discovered a new gene that could lead to breakthroughs in breast and prostate cancer, as well as diabetes.

The gene, called SLIRP, was discovered by a team at the Western Australian Institute for Medical Research's (WAIMR) Laboratory for Cancer Medicine, led by Professor Peter Leedman, in collaboration with Professor Bert O'Malley's team at Baylor College of Medicine in Texas.

"When we baited our hook and went fishing in the breast cancer gene library we came up with SLIRP, much to our surprise, as this gene had not been characterised during the mapping of the human genome," said Professor Leedman.

"What's exciting is that SLIRP has the potential to shut down oestrogen in breast cancer cells and testosterone in prostate cancer cells.

"Most of those cancers depend on the hormones to stay alive, so if we can use SLIRP to block the hormones we may be able to help stop those diseases in their tracks."

Professor Leedman said the discovery could open the door to targeted new treatments for the cancers.

"If we can unravel the mystery of how SLIRP works to turn down the hormone action in cancer cells we could potentially develop so-called 'smart' drugs that zoom in on the gene," he said.

"The benefit is that 'smart' drugs can mean fewer nasty side effects for patients as they target specific genes, not entire areas of the body."

The find could also help researchers create blood tests to diagnose breast and prostate cancer.

"A breakthrough in the techniques available to diagnose breast and prostate cancer would hopefully allow for earlier detection and, importantly, lead to better survival rates," said Professor Leedman.

SLIRP has also been shown to turn down genes involved in energy metabolism.

"With its ability to turn off one of the key regulators of energy metabolism, SLIRP could well lead to progress in tackling diabetes and weight problems," Profes
'"/>

Source:Research Australia


Page: 1 2

Related biology news :

1. Protein discovery could unlock the secret to better TB treatment
2. Purdue proves concept of using nano-materials for drug discovery
3. UCSD discovery may help extend life of natural pesticide
4. Leprosy microbes lead scientists to immune discovery
5. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
6. Researchers make surprise discovery that some neurons can transmit three signals at once
7. Important discovery about second most fatal cancer
8. Harmless virus may hold key to more effective HIV drug discovery
9. Fundamental discovery -- Bone fracture
10. Genetic discovery could lead to drought-resistant plants
11. Gene discovery sheds light on causes of rare disease, cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene discovery opens door tackling disease

(Date:9/22/2014)... Additive manufacturing (AM), or 3D printing, has rapidly ... metal components strong enough for structural applications. However, ... as well as quality standards to test the ... technology. Engineers at the University of Pittsburgh,s Swanson ... modeling and simulation (M&S) technology and new qualification ...
(Date:9/22/2014)... be much more useful in homes, if they could ... the world with cameras and lasers, which have difficulty ... hidden in clutter. A complementary way robots can "sense" ... small ultra-high frequency radio-frequency identification (UHF RFID) tags. Inexpensive ... RFID-equipped robot to search a room for the correct ...
(Date:9/22/2014)... wake of the huge King Fire blazing out of ... Fire is burning in steep terrain in the South ... and the Rubicon Canyon, north of the community of ... and burned onto the Tahoe National Forest north of ... to be minimal on Sept. 22 due to thunderstorms ...
Breaking Biology News(10 mins):Pitt engineers receive grants to enhance additive manufacturing 2Pitt engineers receive grants to enhance additive manufacturing 3New RFID technology helps robots find household objects 2New RFID technology helps robots find household objects 3
... a New Zealand snail and its worm parasite makes ... reproduction in the absence of parasites, say Indiana University ... this week,s Current Biology . The scientists, ... Hypothesis" of sex, which suggests sexual reproduction allows host ...
... received a $3 million grant from the National Science ... Festival and fund the creation and growth of Science ... first annual San Diego Science Festival, held March-April 2009. ... San Diego as a national and global leader in ...
... Cornell Medical Center have discovered a new gene fusion that ... results may lead to more accurate prostate cancer testing and ... -- a hybrid gene formed from two previously separated genes ... cells to grow more quickly than normal cells. The ...
Cached Biology News:Parasitic worms make sex worthwhile 2Parasitic worms make sex worthwhile 3UC San Diego's $3 million NSF grant to fund science festivals 2UC San Diego's $3 million NSF grant to fund science festivals 3Newly discovered gene fusion may lead to improved prostate cancer diagnosis 2Newly discovered gene fusion may lead to improved prostate cancer diagnosis 3
(Date:9/22/2014)... Topical BioMedics, Inc., is celebrating 20 years of ... restoring hope an quality of life and contributing to ... of the innovative cellular biomedicines research that made Topricin® ... , The company was founded in 1994 in a ... of research, and Topricin inventor), Aurora Paradise (COO) and ...
(Date:9/22/2014)... Follow us on LinkedIn ... available in abundance in nature. These natural bio-based ... as shells of crustaceans. The significant commercial interest ... the high percentage of nitrogen present compared to ... industries owing to its exclusive properties such as ...
(Date:9/22/2014)... September 22, 2014 Follow ... to stay young has groomed and nurtured anti-aging ... worldwide. Growing emphasis on appearance maintenance is benefitting ... a neurotoxic protein obtained from the bacterium, Clostridium ... in muscle relaxation. With cosmetic indications for botulinum ...
(Date:9/22/2014)... DUBLIN , Sept. 22, 2014 ... the "Global and Chinese Microcrystalline Cellulose Industry Report ... The Global and Chinese Microcrystalline Cellulose Industry Report 2014 ... state of the global microcrystalline cellulose industry with a ... provides a basic overview of the industry including definitions, ...
Breaking Biology Technology:Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 3Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 4Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 5Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 6Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 2Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 3Strong Demand for Non-Invasive Cosmetic Procedures Drives the Global Botulinum Toxin Market, According to New Report by Global Industry Analysts, Inc. 2Strong Demand for Non-Invasive Cosmetic Procedures Drives the Global Botulinum Toxin Market, According to New Report by Global Industry Analysts, Inc. 3Global and Chinese Microcrystalline Cellulose Industry Report 2014 2
... and HILDEN, Germany , May 25, ... , Prime Standard:,QIA) today announced that it has entered ... pursuant to which QIAGEN has acquired all rights,to 70 ... -based specialized,laboratory center for food analysis. The transaction further ...
... Carolina Conceptions, an infertility practice in Raleigh, NC , announces IRB ... newer technology that is growing in demand. While embryo and sperm freezing have ... achieve the same level of success. , ... Unlike fertilized eggs (embryos) and sperm, which thaw well, the larger egg ...
... ... Mills is the latest company to become a tenant at the North ... partnership between David Murdock and the University of North Carolina System. ... Other tenants on the Campus include: Dole Food Inc, Monsanto, NC State ...
Cached Biology Technology:QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 2QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 3QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 4QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 5QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 6QIAGEN Acquires Comprehensive Portfolio of Molecular Food Safety Tests 7Carolina Conceptions Announces New Egg Freezing Study to Help Women Preserve their Fertility 2General Mills Joins Kannapolis Research Campus 2General Mills Joins Kannapolis Research Campus 3
Bovine Calf Serum...
Collected from animals of U.S. origin.Collected from animals of U.S. origin. *Can be used in cell growth studies and immunoassays. *Sterility tested, * Mycoplasma tested upon request, *Endoto...
NEWBORN CALF SERUM AND PLASMA...
NEWBORN CALF SERUM AND PLASMA...
Biology Products: