Navigation Links
Flies on speed offer insight into the roles of dopamine in sleep and arousal

Methamphetamine, the drug of choice for long-distance truckers and college students pulling all-nighters, appears to do a similar trick for fruit flies, too. This finding is one of several in a new study that demonstrates a critical role for the neurotransmitter dopamine in the modulation of sleep, wake, and arousal states.

The work is reported by Dr. Ralph Greenspan and colleagues at The Neurosciences Institute in San Diego.

The researchers found that long, sleepless nights, heightened locomotor activity, frenetic brain activity, and frenzied (but ultimately ineffective) courtship behavior are all characteristics of fruit flies on methamphetamine, the effects of which are known to act through the neurotransmitter dopamine. In the new work, the researchers showed that genetically engineered flies whose dopamine cells could be turned off experimentally, or flies that have received dopamine inhibitors, show converse behavioral effects to those seen in normal flies that have ingested methamphetamine. The results suggest that the right balance of dopamine is necessary for proper brain functioning, as has been seen in human studies of attention and distraction. Dopamine has been implicated in numerous aspects of brain function in humans and other animals, and many of these brain functions involve the modulation of neuronal activity and the ability to assign proper saliency (or relevance) to sensory stimuli.


'"/>

Source:Cell Press


Page: 1

Related biology news :

1. Flies dont buzz about aimlessly!
2. Sleepless for science: Flies show link between sleep, immune system in Stanford study
3. First atlas of key brain genes could speed research on cancer, neurological diseases
4. Influenza vaccine uses insect cells to speed development
5. Rabies spread speeds up
6. New technique may speed DNA analysis
7. Scientists discover gene that controls speed of tuberculosis development
8. Stressed cells spark DNA repair missteps and speed evolution
9. UW scientists report a new method to speed bird flu vaccine production
10. Agreement will speed research on microbicides for women
11. Treating populations infected with HIV and latent TB could speed the emergence of drug-resistant TB
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Flies speed offer insight into the roles dopamine sleep and arousal

(Date:7/31/2015)... de 2015 La 10 th International Conference ... de BGI del 22 al 25 de octubre de 2015 en ... año, la conferencia celebra su décimo aniversario. Desde su inauguración ... de las reuniones anuales más influyentes del mundo en el ... dinámicas, entusiastas y mejores a nivel científico. ...
(Date:7/30/2015)... 2015 Cellecta, Inc., a U.S.-based provider ... and biomarker discovery, announced the release of its ... all human protein coding genes. CRISPR technology enables ... gene,s function. Cellecta,s new Human Whole Genome CRISPR ... so that researchers can investigate in a single ...
(Date:7/23/2015)... Research and Markets ( http://www.researchandmarkets.com/research/rzzp3v/global_outlook_of ) ... Outlook of the Biometrics Industry 2015 " ... global biometrics market is likely to witness significant ... to the uptake of multiple technologies available. The ... the growth of biometrics in existing applications as ...
Breaking Biology News(10 mins):La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3
... streams and rivers, affecting the number and variety of some ... found. , Rivers and streams are key ecosystems for ... yet little emphasis has been given so far to the ... , Now a twenty-five year study at Llyn Brianne ...
... must prevent the immune system from launching an all-out ... a nutrient "floodgate" that serves to protect against such ... May 4, 2007 issue of the journal Cell, a ... animals lacking a protein enriched in fat cells, called ...
... University of Manchester researchers are ridding diabetic patients of ... with maggots. , Professor Andrew Boulton and his team ... patients whose foot ulcers were contaminated with MRSA and ... period of three weeks, much quicker than the 28-week ...
Cached Biology News:Keeping the immune system from starting a 'food fight' 2Maggots rid patients of MRSA 2
(Date:7/31/2015)... , July 31, 2015 China Cord ... China,s leading provider of cord blood ... cell storage services, today announced that the Company has ... U.S. Securities and Exchange Commission. The filed Form 20-F ... March 31, 2015. The Form 20-F can be accessed ...
(Date:7/30/2015)...   GenoSpace , a leading provider of ... of genomic and other biomedical data, today announced ... company as Vice President of Sales and Marketing. ... "GenoSpace partners with its customers to ... explore complex sets of genomic, phenotypic and other ...
(Date:7/30/2015)... Diego , CA (PRWEB) , ... July 30, ... ... announced the successful completion of a field clinical study of its canine osteoarthritis ... developed together with Aratana Therapeutics (Kansas City, KS) and will be marketed in ...
(Date:7/30/2015)... 2015 Ascendis Pharma A/S (Nasdaq: ... innovative TransCon technology to address significant unmet medical ... six-month Phase 2 study to evaluate the safety ... 53 treatment-naïve, pre-pubertal children with growth hormone deficiency, ... with the top-line results from our Phase 2 ...
Breaking Biology Technology:China Cord Blood Corporation Files Its Annual Report on Form 20-F 2GenoSpace Introduces Matthew Fischer as Vice President of Sales and Marketing 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 2Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 4Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 5Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 6Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 7
... Study Published in the Journal of Clinical Oncology Proves Accurate, ... ... Reaction (RT-PCR), REDWOOD CITY, Calif., June 2 Genomic ... of Clinical Oncology,(JCO) published results of a study confirming RT-PCR ...
... AKIVA, Israel, June 2 ITGI Medical, Ltd.,(TASE: ITGI) ... certified,Over and Under(R) Pericardium Covered Stent (PCS) in the ... covered with a heterologous tissue,designed to set a barrier ... is intended for situations such as degenerated Saphenous Vein,Graft ...
... Perceptive Informatics, the,technology subsidiary of PAREXEL International ... it has integrated its leading medical imaging,technology ... image,management and reporting system provided by Digisonics, ... assessment in clinical studies.,The system provides high-performance ...
Cached Biology Technology:Genomic Health Announces Expansion of Oncotype DX(R) Breast Cancer Test to Include Quantitative Estrogen Receptor (ER) and Progesterone Receptor (PR) Scores 2Genomic Health Announces Expansion of Oncotype DX(R) Breast Cancer Test to Include Quantitative Estrogen Receptor (ER) and Progesterone Receptor (PR) Scores 3Genomic Health Announces Expansion of Oncotype DX(R) Breast Cancer Test to Include Quantitative Estrogen Receptor (ER) and Progesterone Receptor (PR) Scores 4Over and Under(R) Pericardium Covered Stent is now in use in England and Proves Great Deliverability 2Perceptive Informatics Enhances Medical Imaging Capabilities for Assessment of Cardiac Function 2Perceptive Informatics Enhances Medical Imaging Capabilities for Assessment of Cardiac Function 3Perceptive Informatics Enhances Medical Imaging Capabilities for Assessment of Cardiac Function 4
... Assay is an anchorage-independent growth assay in ... stringent assay for detecting malignant transformation of ... with carcinogens or carcinogen inhibitors) are cultured ... for 21-28 days. Following this incubation ...
The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver une...
... Kit uses a simplified procedure and streamlines ... The kit is based on the three ... and sodium bisulfite where cytosine is converted ... innovative in-column desulphonation reaction eliminates several precipitation ...
... Invitrogen makes blotting of E-PAGE Gels easier ... fiber blotting pad and several types of ... fit 8.6 cm x 13.5 cm E-PAGE ... membranes are designed for western transfer of ...
Biology Products: