Navigation Links
Flies on speed offer insight into the roles of dopamine in sleep and arousal

Methamphetamine, the drug of choice for long-distance truckers and college students pulling all-nighters, appears to do a similar trick for fruit flies, too. This finding is one of several in a new study that demonstrates a critical role for the neurotransmitter dopamine in the modulation of sleep, wake, and arousal states.

The work is reported by Dr. Ralph Greenspan and colleagues at The Neurosciences Institute in San Diego.

The researchers found that long, sleepless nights, heightened locomotor activity, frenetic brain activity, and frenzied (but ultimately ineffective) courtship behavior are all characteristics of fruit flies on methamphetamine, the effects of which are known to act through the neurotransmitter dopamine. In the new work, the researchers showed that genetically engineered flies whose dopamine cells could be turned off experimentally, or flies that have received dopamine inhibitors, show converse behavioral effects to those seen in normal flies that have ingested methamphetamine. The results suggest that the right balance of dopamine is necessary for proper brain functioning, as has been seen in human studies of attention and distraction. Dopamine has been implicated in numerous aspects of brain function in humans and other animals, and many of these brain functions involve the modulation of neuronal activity and the ability to assign proper saliency (or relevance) to sensory stimuli.


'"/>

Source:Cell Press


Page: 1

Related biology news :

1. Flies dont buzz about aimlessly!
2. Sleepless for science: Flies show link between sleep, immune system in Stanford study
3. First atlas of key brain genes could speed research on cancer, neurological diseases
4. Influenza vaccine uses insect cells to speed development
5. Rabies spread speeds up
6. New technique may speed DNA analysis
7. Scientists discover gene that controls speed of tuberculosis development
8. Stressed cells spark DNA repair missteps and speed evolution
9. UW scientists report a new method to speed bird flu vaccine production
10. Agreement will speed research on microbicides for women
11. Treating populations infected with HIV and latent TB could speed the emergence of drug-resistant TB
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Flies speed offer insight into the roles dopamine sleep and arousal

(Date:4/24/2014)... recently introduced Clinical OMICs ... of OMICs technologies in clinical settings. These advanced ... transform medical care just as they revolutionized basic ... "GEN,s editors and reporters have written about the ... etc. for years," said John Sterling, editor-in-chief of ...
(Date:4/24/2014)... cheap way of making a high-powered lens that can ... Costing less than a cent, the lenses promise a ... remote areas. , The lens fabrication technique was invented ... (ANU) Research School of Engineering, who collaborated with Dr ... to find ways to transform the lentil-sized lens into ...
(Date:4/24/2014)... University of North Carolina at Chapel Hill have developed ... plaque that is at high risk of breaking off ... is the plaque that builds up in arteries as ... meaning that they are more likely to detach from ... , "Existing state-of-the-art technologies are capable of determining if ...
Breaking Biology News(10 mins):Droplet lens 2New ultrasound device may add in detecting risk for heart attack, stroke 2
... 2009 Landfilled waste decomposes in the absence ... methane. Landfills are classified as the second-largest human-made ... gas contains numerous non-methane hydrocarbons that are either ... biochemical reactions during waste degradation. Microbial methane ...
... tissues need continuous irrigation and drainage. Blood vessels feeding ... via the lymphatic system. While much is known about ... true for lymph vessels. Now though, Norrmn et al. ... drainage construction in the mouse embryo. The ...
... the composition and structure of a needlelike protein complex ... develop new strategies to thwart infection. The research, conducted ... National Laboratory, will be published April 26, 2009, in ... Molecular Biology . The scientists were studying a ...
Cached Biology News:Landfill cover soil methane oxidation underestimated 2Details of bacterial 'injection' system revealed 2
(Date:1/15/2014)... This webinar will focus on EMA and ... in biosimilars. , Regulatory frameworks are evolving many countries ... the complex nature of biopharmaceuticals makes the demonstration of ... challenging. Based on the specific aspects of biosimilar drug ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 Two champions ... continued their sponsorship of an annual competition for middle ... and access to, innovative STEM study. The competition presents ... TEAMS: Tests of Engineering Aptitude, Mathematics, and Sciences ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 2013 was ... Scottsdale’s Brain State Technologies®. They saw continued independent research ... Center who were awarded a $1 million grant from ... in “Brain and Behavior” a peer reviewed journal, Amy ...
(Date:1/15/2014)... Jan. 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") ... with R-Pharm, a leading Russian pharmaceutical company, to develop ... Russian Federation , Turkey ... (CIS). Nemonoxacin is a novel antibiotic for the treatment of ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4
... Real-Time Location System provider for healthcare, is pleased to ... Real-Time Location System . The new messaging better captures ... – , Industry-Leading Accuracy , ... Applications Easy Installation and Maintenance ...
... been mysteriously falling for at least five years in the ... (CCD) is still largely unknown. In a report ... , researchers report that a widely used in-hive medication may ... and that this interaction may be at least partially responsible ...
... and SHENZHEN, China, Nov. 2, 2011 Advanced BioMedical ... internal fixation devices, is pleased to announce the formation ... comprised of three distinguished physicians and scientists. The combined ... critical scientific and strategic input as the Company continues ...
Cached Biology Technology:CenTrak, a Leading Real-Time Location System Provider, Unveils New Branding 2Advanced BioMedical Technologies Inc. Announces Formation of Scientific Advisory Board 2Advanced BioMedical Technologies Inc. Announces Formation of Scientific Advisory Board 3Advanced BioMedical Technologies Inc. Announces Formation of Scientific Advisory Board 4Advanced BioMedical Technologies Inc. Announces Formation of Scientific Advisory Board 5Advanced BioMedical Technologies Inc. Announces Formation of Scientific Advisory Board 6Advanced BioMedical Technologies Inc. Announces Formation of Scientific Advisory Board 7
... antibiotic-based selection system for recombinant identification. Recombinant ... the need for costly color screening. This ... 100% accuracy in recombinant selection. pLivSelect is ... picking. This cloning kit can be used ...
Mouse monoclonal antibody raised against a partial recombinant PRG4. NCBI Entrez Gene ID = PRG4...
Mouse monoclonal antibody raised against a partial recombinant SCARB2. NCBI Entrez Gene ID = SCARB2...
...
Biology Products: