Navigation Links
Fast test for low blood flow in dogs detects early heart trouble

radiation from X-rays, but PET takes nearly one hour to perform, whereas CT scanning is quicker.

To assess if blood flow in dogs could be accurately measured with 64-CT, researchers compared the new scanner with an existing test that is considered to be the gold standard and relies on muscle absorption of microscopic beads in the heart muscle.

Six dogs had surgery to place a clamp around a main artery, cutting in half the blood flow to the heart. After surgery, the dogs were injected with the drug adenosine to speed up their heartbeat and maximize circulation. The dose, they note, was the same as that typically used in humans for routine stress testing: 140 micrograms per kilogram per minute, for five minutes.

When forced to pump faster, healthy heart tissue and surrounding blood vessels will adapt, while unhealthy, blocked ones will slow blood flow. These changes are not usually perceptible to the human eye from the scanned images but can be detected and quantified with CT imaging and computer analysis. Adenosine is commonly used in stress testing, Lardo says, to relax blood vessels in the muscle, which enhances the contrast between normal and abnormal regions of the heart.

After being injected, each of the dogs had a 64-CT scan of its heart and then underwent the standard test for blood flow with chemical beads. The beads, no bigger than 20 micrometers in diameter and called microspheres, were injected into the animal's bloodstream. Previous research has shown that they will lodge into the heart muscle at a fixed rate compared to how fast blood is flowing. Researchers can actually count the number of beads absorbed into the heart tissue to calculate blood flow.

However, calculating blood flow from the 3-D, scanned CT images was more complicated. Researchers used so-called deconvolution mathematical formulae to gauge the speed of blood flow through the heart and its feeding arteries and made separate cal
'"/>

Source:Johns Hopkins Medical Institutions


Page: 1 2 3 4

Related biology news :

1. White blood cell waste disposal system plays critical regulatory role
2. Epstein-Barr virus protein crucial to its role in blood cancers
3. New insight into regulation of blood stem cells
4. Nano-bumps could help repair clogged blood vessels
5. First technology to remove prions that cause vCJD from blood launched
6. Breakthrough isolating embryo-quality stem cells from blood
7. Thai spice helps cut blood sugar swings
8. Study shows humans have ability to track odors, much like bloodhounds
9. Mad cow proteins successfully detected in blood
10. Unexpected lock and key mechanism found for the assembly of tumor blood vessels
11. Redesigned protein accelerates blood clotting
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Fast test for low blood flow dogs detects early heart trouble

(Date:6/29/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/zj7h4f/latin_america ) ... Biomedical Sensors Market - Growth, Trends & Forecasts (2014-2020)" ... America Biomedical Sensors market is estimated at $0.65 billion ... period 2014-2020 The near future will bring ... of each individual. These sensors can be set to ...
(Date:6/25/2015)... -- TAKE Solutions Ltd., a global business technology solutions provider, ... and Trademark Office (USPTO) for its "Method for Optimizing ... Accelerators to reduce the time taken to standardize trial ... the accelerators), thus reducing time to market. ... heart of the patented Clinical Data Standardization Process are ...
(Date:6/24/2015)... 2015 Research and ... the "Huawei Ascend Mate 7 Fingerprint Sensor ... offering. Huawei,s technological choice for the ... than Apple,s and Samsung,s one. The Ascend Mate ... Fingerprint Cards, a main actor in capacitive sensing ...
Breaking Biology News(10 mins):Latin America Biomedical Sensors Market Report 2015-2020 2TAKE Solutions Awarded Patent By USPTO 2Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2
... In a study to be published in the journal ... cyclin A plays an important but previously unknown role in ... ensure the faithful segregation of chromosomes during cell division. , ... splitting into two identical copies. This process happens trillions of ...
... WATERLOO, Ont. (Wednesday, September 11, 2013) A tiny number ... fish in the Great Lakes, according to new research from ... journal Biological Invasions , research from Professor Kim Cuddington ... probability of Asian carp establishment soars with the introduction of ...
... The NTA IPM team has significantly enhanced the environmental ... research and outreach information needed by scientific and regulatory ... crops to beneficial non-target arthropods. Each year the Entomological ... which includes at least one entomologist from the private ...
Cached Biology News:Discovery of cell division 'master controller' may improve understanding and treatment of cancer 2Tiny number of Asian carp could be big problem for the Great Lakes 2Risk assessment team on Bt plants wins Integrated Pest Management Award 2
(Date:7/2/2015)... , July 2, 2015 ... Bio-tech procurement company Amici Procurement has chosen Microsoft ... help it move to Office 365.      ... provides small to medium-sized companies in the bio-tech sector ... aspects of the purchasing cycle to help them obtain ...
(Date:7/1/2015)... RESEARCH TRIANGLE PARK, N.C. and ... -- Leading agricultural research firm AgBiome, and Genective, key ... partnership to accelerate the discovery of new generations ... new traits for insect control to counter the ... to partner with Genective, aligning AgBiome,s unique insect ...
(Date:7/1/2015)... ALTO, Calif. , July 1, 2015 /PRNewswire/ ... focused on the development of groundbreaking drugs to ... (ALS), announced today that Robert G. Miller ... Center at Sutter Health,s California Pacific Medical Center ... The ALS Association for $1.5 million to help ...
(Date:7/1/2015)... 1, 2015 InferMed , ... will ... evidence-based clinical s olutions suite   ... information products and services, announced today the acquisition of  InferMed ... (CDS) technology company. InferMed,s Arezzo technology supports clinicians ...
Breaking Biology Technology:Biotech Procurement Company Moves to Office 365 with iomart 2AgBiome and Genective collaborate to create novel insect-resistant crops 2Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 2Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 4Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 2Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 4
... ROCKVILLE, Md., Feb. 10, 2011 Ariadne, a ... today that Georgetown University signed a site license ... continuing its goal of adopting and applying innovative ... Pathway Studio to aid researchers in their efforts ...
... /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Amex: YMI, TSX: ... diverse portfolio of promising hematology and cancer-related products at ... results for the second quarter of fiscal 2011, ended ... of Hematology Annual Meeting in December 2010, we presented ...
... Qteros, Inc., the developer of a unique and ... the lowest-cost production of cellulosic ethanol, today announced a ... Europe for members of its senior management team. ... and Engineering, will present on a panel entitled, "Lessons ...
Cached Biology Technology:Georgetown Lombardi Comprehensive Cancer Center Taps Ariadne for G-DOC Pathway Data and Tools 2Georgetown Lombardi Comprehensive Cancer Center Taps Ariadne for G-DOC Pathway Data and Tools 3YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 2YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 3YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 4YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 5YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 6YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 7YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 8YM BioSciences Reports Fiscal Second Quarter 2011 Operational and Financial Results 9Qteros Management to Present at Notable Alternative Energy Conferences in February 2
BD BioCoat Gelatin 100 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of gelatin....
... internal standard for the quantification of 5-OxoETE ... is a polyunsaturated keto acid formed by ... It stimulates cytosolic calcium levels in neutrophils ... selectively stimulates the migration and degranulation of ...
... used as an internal standard for the ... mass spectrometry. 5-OxoETE is a polyunsaturated keto ... in human neutrophils. It stimulates cytosolic calcium ... 2 nM. 5-OxoETE selectively stimulates the migration ...
... size markers are a mixture of Strep•Tag® ... 100 kDa. The markers provide precise size ... staining with Coomassie blue. Because each of ... the markers can also be detected by ...
Biology Products: