Navigation Links
FSU biologists uncover mechanisms that shape cells for better or worse

In a landmark study, biologists at Florida State University have uncovered a specific genetic and molecular mechanism that causes cell polarity -- the asymmetric shape or composition critical to a cell's proper functioning. Their findings in fruit fly eggs may help to clarify how muscular dystrophy and some cancers develop in humans.

That's because many of the genes involved in the cell-to-cell communication that triggers the development of cell polarity in Drosophila oocytes (unfertilized fruit fly eggs) also are known players in the pathogenesis of those diseases.

The research performed by FSU Assistant Professor Wu-Min Deng and doctoral student John S. Poulton in the department of biological science could foster a better overall understanding of polarity and how it develops -- and why it doesn't, sometimes with dire consequences -- in other types of cells and organisms.

Results from the FSU study are described in the Aug. 14 online edition of the journal PNAS (Proceedings of the National Academy of Sciences).

"We have identified a novel component in the polarization of the fruit fly egg and the signals that determine the anterior-posterior positioning of its head and abdomen," said Deng.

"Such a discovery in the biological model provided by Drosophila oocytes has broad implications in humans, where, for example, neurons in the brain are designed, or polarized, to interpret information from the sense organs, and intestinal cells are polarized to take up nutrients and move them into the bloodstream," he said.

Poulton explained that in order to ensure cell polarity in the Drosophila oocyte, the cells surrounding it activate a classic signaling pathway known as the Epidermal Growth Factor Receptor (EGFR) in a process that is also essential to development in humans and a wide range of other organisms.

"Our study shows that EGFR activation in the cells surrounding the fruit fly
'"/>

Source:Florida State University


Page: 1 2

Related biology news :

1. Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
2. GeneNotes - A novel information management software for biologists
3. NYU biologists map out early stages of embryo formation
4. FSU biologists describe key role of signal-transcribing gene during cell cycle
5. High-tech tags on marine animals yield valuable data for biologists and oceanographers
6. UCSD biologists find new evidence for one-way evolution
7. UC San Diego biologists solve plant growth hormone enigma
8. NYU biologists identify gene that coordinates two cellular processes
9. MIT biologists solve vitamin puzzle
10. Yale biologists trick viruses into extinction
11. Brown cancer biologists identify major player in cell growth
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: FSU biologists uncover mechanisms that shape cells for better worse

(Date:5/27/2015)... , May 27, 2015   ... medication safety systems and image documentation solutions ... of comprehensive, technologically-advanced automation solutions, is pleased ... integration. The Codonics® Safe Label System® (SLS), ... in conjunction with the Omnicell Anesthesia Workstation, ...
(Date:5/26/2015)... Research and Markets ( ... "Saudi Arabia Biometric Systems Market Forecast and ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The biometric systems market in ... to grow at over 22% CAGR through 2020 ... the surging demand for better biometric technologies in ...
(Date:5/25/2015)... May 25, 2015  Australia,s market for wearable technologies ... 2014 saw the advent of several trials and prototypes. ... 2015 is expected to ignite interest in wearables as ... Australia . This in turn will spur ... drive new partnerships amongst vendors and distributors. ...
Breaking Biology News(10 mins):Codonics and Omnicell Expand Partnership 2Codonics and Omnicell Expand Partnership 3Codonics and Omnicell Expand Partnership 4Saudi Arabia Biometric Systems Market Forecast and Opportunities, 2020 with Morpho Safran, ZK Technlogy, and Suprema Dominating 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 3Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 4
... described in an advance online publication in Nature Genetics ... technique which, combined with other approaches, may explain 40 to ... just a few years, proposes the study,s lead investigator. This ... Seattle, will potentially allow clinicians to "lift the hood on ...
... seed to decide on the perfect time to germinate has ... biologists at The University of Nottingham have also discovered that ... important decision in the life cycle of plants when ... genetic mechanisms that plants use to detect and respond to ...
... This release is available in German . ... exciting experience," say Joachim Fischer and Tolga Ergin. For about ... Professor Martin Wegener at KIT,s Center for Functional Nanostructures (CFN) ... cloak to such an extent that it is also effective ...
Cached Biology News:New technique promises to 'lift the hood’ on autism 2New technique promises to 'lift the hood’ on autism 3New technique promises to 'lift the hood’ on autism 4Nottingham scientists reveal genetic 'wiring' of seeds 2Karlsruhe invisibility cloak: Disappearing visibly 2
(Date:5/28/2015)... DryLet, LLC a biotechnology company providing ... animal waste reduction, bioremediation, wastewater treatment, aquaculture and ... plants and restaurant kitchen settings, announced today it ... 3-5 in Des Moines, Iowa. , ManureMagicâ„¢ was ... Journal article because of its industry-leading qualities and ...
(Date:5/28/2015)... 2015 BioNorth Texas (BioNorthTX), an ... the life sciences industry in northern region of ... at The Foundry in Dallas on April 27, ... together a broad spectrum of biotech professionals from ... early successes in partnering with key life sciences ...
(Date:5/28/2015)... , May 28, 2015  PDS Biotechnology Corp. ... immunotherapy treatment targeting HPV-16, has generated strong T-cell ... Currently, pre-cervical cancer is treated by surgical removal ... and effective non-surgical alternative. Results show that it ... to recognize, target, and kill precancerous and cancerous ...
(Date:5/28/2015)... 2015 RXi Pharmaceuticals Corporation (NASDAQ: RXII ... innovative therapeutics, primarily in the areas of dermatology and ... of 26 million units at a price to the ... approximately $10.4 million. Each unit consists of (i) one ... right to purchase 0.50 of a share of common ...
Breaking Biology Technology:DryLet to Showcase Patented ManureMagicâ„¢ at the 2015 World Pork Expo, June 3-5 in Des Moines, Iowa 2BioNorthTX Holds Inaugural Board of Directors Meeting 2BioNorthTX Holds Inaugural Board of Directors Meeting 3PDS Biotechnology reports positive Phase I clinical trial results in proprietary HPV-Cancer Immunotherapy 2RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 3
... , LELYSTAD, ... biotechnology company focusing on protein mimicking,technology for the generation of ... Ph.D. as new Chief Executive Officer. , ... corporate functions and,the overall management and strategic direction of the ...
... , NANJING, China, Dec. ... (NYSE: SCR ), a leading pharmaceutical company,specializing ... proprietary pharmaceuticals in China, today announced that 105 of,its ... List,("NDRL"), which was issued by China,s Ministry of Human ...
... ... announced that he has joined Carolina Eyecare Physicians and has launched his ... Group. Dr. Solomon is a proven LASIK, lens implant, and cataract ... improving vision correction surgery. He is a member of Trusted LASIK ...
Cached Biology Technology:Dutch Biotech Company Pepscan Appoints New CEO 2Simcere Announces 105 Drugs Included in China's National Drug Reimbursement List 2Simcere Announces 105 Drugs Included in China's National Drug Reimbursement List 3Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 2Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 3Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 4Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 5Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 6
... and analysis software for electrophysiology ... Contains powerful stimulus generation capabilities ... including automated waveform feature detection ... many electrophysiology specific functions including ...
A431 cells Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
A431 cells stimulated with EGF Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
... Certified USDA Research Registered OLAW Assured AAALAC ... AALAS Certified Technicians Documentation ... Upon Request Focus CRP is ... your custom immunology service needs. We ...
Biology Products: