Navigation Links
Diabetes slows nerve recovery after heart transplant

Diabetes has a detrimental effect on a person's ability to recover from a heart transplant, notes a study in the September Journal of Nuclear Medicine.

"Using positron emission tomography (PET) and the transplanted heart as a very specific model to study the regenerative capacity of the heart's sympathetic nervous system, we determined that reinnervation--or the heart's ability to develop new nerves to replace damaged ones--is slower in diabetic patients," said Frank M. Bengel, a visiting associate professor of radiology and the director of cardiovascular nuclear medicine at Johns Hopkins Medicine's Russell H. Morgan Department of Radiology and Radiological Science in Baltimore, Md. "Our results confirm a detrimental effect of diabetes on the potential for recovery of sympathetic nerve fibers of the heart," added the co-author of "Effect of Diabetes Mellitus on Sympathetic Neuronal Regeneration Studied in the Model of Transplant Reinnervation."

"A better understanding of the importance of nervous system abnormalities and an imaging technique to precisely characterize nerve damage may be of value to guide future therapeutic efforts aimed at reducing cardiac risk with diabetes mellitus patients," explained Bengel, who was an associate professor at the Technical University of Munich, where the study was performed, prior to his move to Johns Hopkins. "Even if a transplant recipient is suffering from diabetes, there is still a chance for reinnervation--just at a slower speed," he added. "Unfortunately, there are no techniques developed yet that speed the nerve regeneration process," he said.

Currently, nuclear medicine techniques (such as PET) are the only imaging techniques that can measure the presence and function of the sympathetic nervous system of the heart, said Bengel. "There are invasive methods that allow for the measurement of neurotransmitters released to the blood, offering indirect conclusions about the presence, storage and releas
'"/>

Source:Society of Nuclear Medicine


Page: 1 2

Related biology news :

1. FDA Approves New Drug to Treat Type I and Type II Diabetes
2. First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes
3. Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
4. Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes
5. Diabetes researchers pioneer islet cell xenotransplantation in primate studies
6. Diabetes hits 275 Australians each day as pandemic spreads
7. Diabetes research takes wing thanks to long-lived fruit fly
8. Cancer drug slows poxvirus in mice
9. Stress substantially slows human bodys ability to heal
10. Cell therapy slows progression of an inherited neurological disease; Improves motor skills in mice
11. Protein found that slows hepatitis C growth in liver cells
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Diabetes slows nerve recovery after heart transplant

(Date:9/21/2014)... such as mussels and barnacles secrete very sticky proteins ... even underwater. Inspired by these natural adhesives, a team ... be used to repair ships or help heal wounds ... adhesives, the MIT researchers engineered bacteria to produce a ... well as a bacterial protein found in biofilms ...
(Date:9/19/2014)... new resource unveiled today by researchers from several ... Dublin provides both experienced and aspiring researchers with ... and operate robots made from soft, flexible materials. ... laser cutters, and other advances in manufacturing technology, ... field. Using principles drawn from conventional rigid robot ...
(Date:9/19/2014)... the sake of fairness per se but in order ... Frans de Waal, PhD, and Sarah Brosnan, PhD, co-authors ... is defined as a negative reaction to unequal outcomes. ... , Their conclusion comes after the co-authors reviewed more ... it is the evolution of forestalling partner dissatisfaction with ...
Breaking Biology News(10 mins):Engineered proteins stick like glue -- even in water 2Engineered proteins stick like glue -- even in water 3Soft robotics 'toolkit' features everything a robot-maker needs 2Evolution of responses to (un)fairness 2Evolution of responses to (un)fairness 3
... unknown movements of a set of specialized cells, Whitehead ... immune system mounts a successful defense against hostile, ever-changing ... the activity inside structures known as germinal centers (GCs), ... of a foreign virus or bacteria. Within the GCs, ...
... In a study published in Cell Research , ... the genome sequencing and analysis of the endangered Chinese ... published crocodilian genome, providing a good explanation of how ... determination (TSD). The Chinese alligator is a ...
... The Netherlands , August 9, 2013 ... employment market, recruiters and HR specialists need to increase ... Microsoft Dynamics and WCC ELISE for organisations keen to ... Today,s recruiters must grapple with ever-increasing amounts ...
Cached Biology News:Helper cells aptly named in battle with invading pathogens 2Whole-genome sequencing uncovers the mysteries of the endangered Chinese alligator 2Most Efficient Matching in Recruitment With CRMATCH and ELISE 2
(Date:9/18/2014)... BELLINGHAM, Washington, USA (PRWEB) September 18, 2014 ... of Representatives of a bill designed to stimulate development ... high-value jobs is being praised by leaders of ... The bill, the Revitalizing American Manufacturing and Innovation (RAMI) ... vote. The bill’s authors have said they are optimistic ...
(Date:9/18/2014)... 2014 /PRNewswire-iReach/ -- DeepResearchReports.com adds "2014 Deep Research ... and "2014 Deep Research Report on Global and ... database. Photo - http://photos.prnewswire.com/prnh/20140918/147058 ... Global and China Acetic Acid Industry" is a ... China and Global Acetic Acid Market. ...
(Date:9/18/2014)... Ireland , September 18, 2014 ... and Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has ... "Biocompatible Materials - Global Strategic Business ... ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes ... in US$ Million by the following ...
(Date:9/18/2014)... , Sept. 18, 2014 Research ... "Global and Chinese Stem Cell Industry Report, 2014-2017" ... cells are undifferentiated biological cells that can differentiate into ... more stem cells. Stem cell therapy can be applied ... hematological system disease), nervous system diseases, damage or lesion ...
Breaking Biology Technology:House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Global and Chinese Stem Cell Industry Report, 2014-2017 2Global and Chinese Stem Cell Industry Report, 2014-2017 3
... 96 temperature,cyclers , Michelle Cayouette Jane ... ,Stratagene Cloning Systems, Inc. , With the introduction of ... 96 temperature cyclers, researchers can begin running oil-free,PCR ... is supplied,with a software upgrade card, which provides more ...
... , Novel method streamlines blood DNA purification for PCR applications , ... , , ... , Stratagene , , ... Using the new DNA Stat blood kit, it is easy , ...
... protein purification and native eukaryotic amino acid ... John Bauer ,Stratagene Cloning Systems, Inc. ... system features rapid and high-yield,production of recombinant ... (LIC) for efficient and directional cloning of ...
Cached Biology Technology:Oil-Free PCR Using the Hot Top Assembly 2Oil-Free PCR Using the Hot Top Assembly 3Oil-Free PCR Using the Hot Top Assembly 4Oil-Free PCR Using the Hot Top Assembly 5Oil-Free PCR Using the Hot Top Assembly 6Oil-Free PCR Using the Hot Top Assembly 7Fast and Easy Isolation of PCR-Ready Genomic DNA from Whole Blood 2Fast and Easy Isolation of PCR-Ready Genomic DNA from Whole Blood 3Fast and Easy Isolation of PCR-Ready Genomic DNA from Whole Blood 4Fast and Easy Isolation of PCR-Ready Genomic DNA from Whole Blood 5New Yeast Cloning System for Producing Proteins with Native Amino Acid,Sequences 2New Yeast Cloning System for Producing Proteins with Native Amino Acid,Sequences 3New Yeast Cloning System for Producing Proteins with Native Amino Acid,Sequences 4New Yeast Cloning System for Producing Proteins with Native Amino Acid,Sequences 5
... The ProteoSpin Detergent Clean-up Micro Kit provides ... removal of SDS, Triton X-100 and other detergents ... spin-column chromatography using Norgens patented protein resin as ... processing 2 50 g of either acidic or ...
Compound(s) screened through any number of client selected assays. Client also selects number of concentrations and replicates....
... hematopoietic stem cells called monocytes. Osteoclasts resorb ... and lowering the surrounding pH to an ... mineral is then solubilized and the collagen ... primarily by Macrophage Colony-Stimulating Factor (M-CSF) and ...
Values of steady state parameters for enzyme activities are determined....
Biology Products: