Navigation Links
'Cellular antennae' on algae give clues to how human cells receive signals

By studying microscopic hairs called cilia on algae, researchers at UT Southwestern Medical Center have found that an internal structure that helps build cilia is also responsible for a cell's response to external signals.

Cilia perform many functions on human cells; they propel egg and sperm cells to make fertilization possible, line the nose to pick up odors, and purify the blood, among other tasks.

With such a range of abilities, cilia serve as both motors and "cellular antennae," said Dr. William Snell, a professor of cell biology at UT Southwestern and senior author of new research on cilia published in the May 5 issue of Cell.

Genetic defects in cilia can cause people to develop debilitating kidney disease or to be born with learning disabilities, extra fingers or toes, or the inability to smell.

But no one really knows how cilia work, or, in some parts of the body, what their function is.

"There are cilia all over within our brain, and we don't have a clue about what they're doing," Dr. Snell said.

He and his team use the microscopic green alga, Chlamydomonas reinhardtii, which has two individual cilia. This alga allows researchers to manipulate genes and study the resulting effects on cilia in a way that would be impossible in animals such as mice.

"Chlamy is one of the few model organisms in which it's possible to do these kinds of studies," Dr. Snell said.

Normally, cilia ?also called flagella ?are built and maintained by an internal bidirectional, escalator-like system that ferries molecules to and from the tips by a process called intraflagellar transport, or IFT.

The UT Southwestern researchers used a mutant temperature-sensitive strain of the alga that behaved normally at lower temperatures. At higher temperatures, however, the IFT process stopped, and its components disappeared from the cilia. The cilia themselves were still able to beat, or move back and forth, for about 40 m
'"/>

Source:UT Southwestern Medical Center


Page: 1 2

Related biology news :

1. Evidence of 600-million-year old fungi-algae symbiosis discovered in marine fossils
2. Deep sea algae connect ancient climate, carbon dioxide and vegetation
3. The secret life of algae
4. A new male-specific gene in algae unveils an origin of male and female
5. Detecting microalgae in coastal waters
6. Chemicals in brown algae may protect against skin cancer
7. Florida Tech explores microalgae for biofuel
8. Common algae helps illustrate mammalian brain electrical circuitry
9. Insight into DNAs weakest links may yield clues to cancer biology
10. High-powered gene profiles provide clues to genes involved in common form of lung cancer
11. Genetic links could unlock clues to leading cause of blindness
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cellular antennae algae give clues how human cells receive signals

(Date:8/21/2014)... significant reduction in smog-producing toxins in past decade, ... new study shows that while the Greater Toronto ... toxins that contribute to smog, the city continues ... pollution., Smog, which can cause or aggravate health ... is produced by a set of complex photochemical ...
(Date:8/21/2014)... dandruff, eczema and other itchy, flaky maladies in humans ... Hawaiian coral reefs and the extreme environments of arctic ... the scientific journal PLOS Pathogens considers the ... genus Malassezia in light of new insights ... world. , University of Hawai,i at Mānoa scientist Anthony ...
(Date:8/21/2014)... AWI geologist Juliane Mller the Fram Strait is a key ... of this passage between Greenland and Svalbard warm Atlantic water ... the west side cold Arctic water masses and sea ice ... Atlantic. A considerable portion of the Atlantic water cools here ... layers. The circulation of the water caused in this manner ...
Breaking Biology News(10 mins):Despite a significant reduction in smog-producing toxins, the Greater Toronto Area still violates Canada's standards for ozone air pollution 2From dandruff to deep sea vents, an ecologically hyper-diverse fungus 2Arctic sea ice influenced force of the Gulf Stream 2Arctic sea ice influenced force of the Gulf Stream 3
... Fifty-nine leading life scientists from Europe and around the ... Organization (EMBO) for their proven excellence in research. Fifty-one ... Europe and neighbouring countries, while eight equally respected scientists ... as Associate Members, bringing the current membership total to ...
... herbicide that is effective at killing broadleaf weeds in ... Illinois and other Midwestern states, may finally have a ... developed a new grape called Improved Chancellor which is ... 1946, 2,4-Dichlorophenoxyacetic or 2, 4-D was introduced. It was ...
... is available in Spanish . An ... the Institute for Research in Biomedicine (IRB Barcelona) and ... (ICIQ, Tarragona), have discovered a substance with the capacity ... certain mutations that promote the appearance of cancer. Giralt, ...
Cached Biology News:EMBO honors 59 leading life scientists 2Herbicide-resistant grape could revitalize Midwest wine industry 2Herbicide-resistant grape could revitalize Midwest wine industry 3Design of a compound that stabilizes the main natural suppressor of tumors 2
(Date:8/22/2014)... August 22, 2014 Nerium International, ... is in the spotlight again. Nerium will showcase ... its NeriumFirmTM Body Contouring Cream to Hollywood’s elite ... Creations during the 66th Primetime Emmy® Awards. , ... extract, third-party clinical trials show that NeriumAD night ...
(Date:8/21/2014)... 2014 DNA vaccine pioneer Immunomic ... development of JRC-LAMP-vax, an innovative and safe potential treatment ... studies began this month in Hawaii, moving the world ... The Japanese red cedar releases pollen that causes devastating ... Cedar pollen wreaks similar havoc in Colorado, New Mexico ...
(Date:8/21/2014)... , August 21, 2014 ... http://www.researchandmarkets.com/research/3zh3q8/global_hormone ) has announced the addition of ...  report to their offering.       ... as hormone therapy, is a means of ... produced by the body. This type of ...
(Date:8/21/2014)... , Aug. 21, 2014  Decision Resources Group ... Brazil and Mexico ... of several newly approved agents, the anticipated label ... and the launch of emerging biologics will substantially ... particular, the emerging IL-5 inhibitors will introduce a ...
Breaking Biology Technology:Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 3Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 2Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 3Relief for Allergy Sufferers Finally in Sight: Immunomic Therapeutics Closes in on Treatment for Hay Fever in Japan, U.S. 4Global Hormone Replacement Therapy Market 2014-2018: Key Vendors are Actavis, Bayer, Merck & Co, Novartis and Novo Nordisk 2Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 2Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 3
... March 10 Campbell Alliance, the leading ... industry, today announced that Ashwin Dandekar, Vice President, Brand ... Summit USA on March 30 and 31, 2009 at ... Dr. Dandekar will also present a workshop at EyeForPharma,s ...
... Off-Label Use of Avastin Will Take Market Share ... to a New Report from Decision ResourcesWALTHAM, Mass., ... world,s leading research and advisory firms for pharmaceutical ... percent growth in the age-related macular degeneration (AMD) ...
... NxStage Medical, Inc. (Nasdaq: NXTM ), a ... Jeffrey H. Burbank, Chief Executive Officer, will be presenting ... on Monday, March 16, 2009 at the Marriot Copley ... for Monday, March 16th at 4:40 p.m. ET. ...
Cached Biology Technology:Campbell Alliance Brand Management Practice to Present at EyeForPharma's Oncology Summit USA and Oncology Market Access Europe Conference 2Campbell Alliance Brand Management Practice to Present at EyeForPharma's Oncology Summit USA and Oncology Market Access Europe Conference 3Robust Annual Growth Through 2012 in the Age-Related Macular Degeneration Market Will Be Driven by Expanding Use of Lucentis in Europe 2Robust Annual Growth Through 2012 in the Age-Related Macular Degeneration Market Will Be Driven by Expanding Use of Lucentis in Europe 3NxStage to Present at the Cowen and Company 29th Annual Healthcare Conference 2
Integrins Sampler Kit 10g each...
Protein Tyrosine Phosphatase Sampler Kit 10g each...
... reagent for Virus isolation ... unique water insoluble Elastomeric ... and chaotropes; Engineered to ... viruses while preserving infectivity; ...
Caveolin Sampler Kit 10g each...
Biology Products: