Navigation Links
'Cellular antennae' on algae give clues to how human cells receive signals

By studying microscopic hairs called cilia on algae, researchers at UT Southwestern Medical Center have found that an internal structure that helps build cilia is also responsible for a cell's response to external signals.

Cilia perform many functions on human cells; they propel egg and sperm cells to make fertilization possible, line the nose to pick up odors, and purify the blood, among other tasks.

With such a range of abilities, cilia serve as both motors and "cellular antennae," said Dr. William Snell, a professor of cell biology at UT Southwestern and senior author of new research on cilia published in the May 5 issue of Cell.

Genetic defects in cilia can cause people to develop debilitating kidney disease or to be born with learning disabilities, extra fingers or toes, or the inability to smell.

But no one really knows how cilia work, or, in some parts of the body, what their function is.

"There are cilia all over within our brain, and we don't have a clue about what they're doing," Dr. Snell said.

He and his team use the microscopic green alga, Chlamydomonas reinhardtii, which has two individual cilia. This alga allows researchers to manipulate genes and study the resulting effects on cilia in a way that would be impossible in animals such as mice.

"Chlamy is one of the few model organisms in which it's possible to do these kinds of studies," Dr. Snell said.

Normally, cilia ?also called flagella ?are built and maintained by an internal bidirectional, escalator-like system that ferries molecules to and from the tips by a process called intraflagellar transport, or IFT.

The UT Southwestern researchers used a mutant temperature-sensitive strain of the alga that behaved normally at lower temperatures. At higher temperatures, however, the IFT process stopped, and its components disappeared from the cilia. The cilia themselves were still able to beat, or move back and forth, for about 40 m
'"/>

Source:UT Southwestern Medical Center


Page: 1 2

Related biology news :

1. Evidence of 600-million-year old fungi-algae symbiosis discovered in marine fossils
2. Deep sea algae connect ancient climate, carbon dioxide and vegetation
3. The secret life of algae
4. A new male-specific gene in algae unveils an origin of male and female
5. Detecting microalgae in coastal waters
6. Chemicals in brown algae may protect against skin cancer
7. Florida Tech explores microalgae for biofuel
8. Common algae helps illustrate mammalian brain electrical circuitry
9. Insight into DNAs weakest links may yield clues to cancer biology
10. High-powered gene profiles provide clues to genes involved in common form of lung cancer
11. Genetic links could unlock clues to leading cause of blindness
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cellular antennae algae give clues how human cells receive signals

(Date:1/22/2015)... and POINT ROBERTS, Washington , January 20, ... leading sectors including technology and tech stocks, releases video from ... master pickpocket and security consultant Apollo Robbins . ... talks about the Wocket™ biometric smart wallet, a product of ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... addition of the "Global Wearable Technologies Market ... Share, Overview, Trends and Forecast 2014-2020" report ... Technologies are smart devices that can be worn ...
(Date:12/24/2014)... , Dec. 23, 2014  Since its launch in December 2014, the ... eliminate the pain of trying to remember their usernames and ... fused to their smartphones. To assist people who have struggled ... company that created 1U and focuses on redefining identity, announced ...
Breaking Biology News(10 mins):Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3
... Minnesota Partnership for Biotechnology and Medical Genomics announced ... 2013 Discovery Transformation Grant Program. Together, the selected ... to support their work in diabetes research. Minnesota ... Minnesota Legislature With an eye on funding ...
... genome in human lung cells will ensure safe research on ... of Medicine at Mount Sinai. Details of their "molecular ... to humans, are published in Nature Biotechnology . ... in human lung cells to latch on to these viruses ...
... Swiss men prefer beer when they drink alcohol, taking in ... form of the beverage. Far fewer (around five percent) prefer ... alcoholic beverages and a riskier approach to alcohol or other ... and Preventive Medicine at the University of Zurich and Lausanne ...
Cached Biology News:4 projects awarded Discovery Transformation Grant funding by Minnesota Partnership 24 projects awarded Discovery Transformation Grant funding by Minnesota Partnership 3Scientists develop method that ensures safe research on deadly flu viruses 2Scientists develop method that ensures safe research on deadly flu viruses 3Young beer-drinkers binge-drink more frequently 2
(Date:2/27/2015)... SUMMERLAND, British Columbia , Feb. 27, 2015 /PRNewswire/ ... a leader in synthetic biology, today announced it has ... (OSF), the pioneering agricultural company behind the ... apple. Through the acquisition, Intrexon expands its food programs ... and convenient for consumers while providing economic benefit throughout ...
(Date:2/27/2015)... , Feb. 27, 2015 A paper ... NCATS rare-diseases portfolio " in Science Translational ... financing technique to reduce the risk associated with ... potentially unlock new levels of funding for developing ... of a unique collaboration between scientists at the ...
(Date:2/27/2015)... 27, 2015 Immunovaccine Inc. (“Immunovaccine”) ... company, today announced that the U.S. Food and ... Track designation and Phase I clinical trials of ... the mutual co-development agreement signed with Gilead Life ... designation for the DPX-Survivac. , “We have been ...
(Date:2/27/2015)... 27, 2015 Bionomics Limited (ASX:BNO, ADR:BMICY) is ... of BNC105 in patients with metastatic renal cancer at ... Florida . The data will be presented by ... Hope Comprehensive Cancer Center in California ... new data identifies Ferritin and IL-8 as two baseline ...
Breaking Biology Technology:Intrexon to Acquire Okanagan Specialty Fruits 2Intrexon to Acquire Okanagan Specialty Fruits 3Intrexon to Acquire Okanagan Specialty Fruits 4New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 3New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 4Immunovaccine Inc. (TSX: IMV) receives Fast Track and Phase I trial approval for Ebola and Anthrax vaccine programs, signs co-development agreement with Gilead Sciences 2Immunovaccine Inc. (TSX: IMV) receives Fast Track and Phase I trial approval for Ebola and Anthrax vaccine programs, signs co-development agreement with Gilead Sciences 3New BNC105 Biomarker Data to be Presented at US Cancer Conference 2New BNC105 Biomarker Data to be Presented at US Cancer Conference 3New BNC105 Biomarker Data to be Presented at US Cancer Conference 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 5
... Corporation,(Nasdaq: KNSY ) will present at the ... Forum at The Ritz-Carlton San Francisco on,Tuesday, September ... President & CEO, will deliver the,Company,s presentation, beginning ... be available on the company,s website,( http://www.kenseynash.com ) ...
... Calif., Sept. 12 Bionovo, Inc.,(Nasdaq: BNVI ), a ... effective drugs in the areas of women,s health and,cancer, announced ... presenting at A.G. Edwards, 2nd Annual Emerging Growth Conference in ... AM ET on Tuesday,September 18, 2007 at the New York ...
... AT 10:00AM EDT, EDMONTON, BELLEVUE, WASHINGTON, Sept. ... (TSX: BRA) (the "Company") today announced that,the Company,s ... change its,jurisdiction of incorporation from the federal jurisdiction ... United States of America through a plan of,arrangement. ...
Cached Biology Technology:Kensey Nash to Present at the Sidoti Sixth Annual West Coast Emerging Growth Institutional Investor Forum Conference 2Bionovo to Present at A.G. Edwards' 2nd Annual Emerging Growth Conference 2007 2Biomira Announces Plan to Reincorporate in the United States 2Biomira Announces Plan to Reincorporate in the United States 3Biomira Announces Plan to Reincorporate in the United States 4Biomira Announces Plan to Reincorporate in the United States 5Biomira Announces Plan to Reincorporate in the United States 6
... Automatic High Sensitivity Laboratory Osmometer for both 0.2 and 2.0 mL samples for ... and record keeping. Bar code reading capability with optional scanner. RS-232 port. ... ... ...
MAb to Hu-IFN-Gamma RC2 (CD118), NON-Neutralizing, Clone MMHGR-2 Binds to but does not neutralize human interferon gamma receptor...
Recombinant Rat CINC-2 alpha, CF...
RAT ANTI MOUSE F4/80 ANTIGEN:BIOTIN Immunogen: Thioglycollate stimulated peritoneal macrophages from C57/BL mice...
Biology Products: