Navigation Links
BGSU biologist trying to crack microscopic code

Dr. Ray Larsen is trying to learn a second language. The Bowling Green State University biologist wants to crack the communication code of proteins, especially the ones whose "talking" aids and abets disease.

"Proteins interact; they 'talk' to each other," the associate professor says. "It's how they know what to do, and it's how most of the things that need to happen for living organisms get done."

Over the past three years he has received $300,000 in funding from the National Science Foundation for his research.

What talking proteins have to do with infectious disease is a story that unfolds in the submicroscopic world of molecular biology. It starts with bacteria, which are cloaked by an outer membrane--a defensive barrier against the harsh elements of their environment, whether toxins in nature or the protective antibodies of an infected host. Specific proteins interact to support this shield, and knowing how they communicate would provide a key to disabling it, Larsen says.

Once communication questions are answered, a goal is to develop drugs to break the barrier, rendering the bacteria more susceptible to the human body's natural defenses--antibodies--as well as certain antibiotics, he points out.

While keeping potential dangers out, the outer membrane must also be porous enough to allow nutrients in, he continues. As an analogy, he cites a house with a yard and a chain-link fence that "keeps the dogs out of the roses but lets the butterflies through."

A short distance separates the outer membrane and the rest of the organism. How the bacteria maintain their barrier when it's physically removed from the rest of the cell, and thus separated from its energy source, is where his interest lies.

"The barrier is not self-sustaining, so the bacteria must export energy to it," says Larsen, referring to protein systems that take cellular energy and use it to support the outer membrane. "It's kind of like get
'"/>

Source:Bowling Green State University


Page: 1 2 3

Related biology news :

1. Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
2. GeneNotes - A novel information management software for biologists
3. NYU biologists map out early stages of embryo formation
4. FSU biologists describe key role of signal-transcribing gene during cell cycle
5. Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
6. High-tech tags on marine animals yield valuable data for biologists and oceanographers
7. UCSD biologists find new evidence for one-way evolution
8. FSU biologist says new dinosaur is oldest cousin of Tyrannosaurus rex
9. UC San Diego biologists solve plant growth hormone enigma
10. FSU biologists uncover mechanisms that shape cells for better or worse
11. NYU biologists identify gene that coordinates two cellular processes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: BGSU biologist trying crack microscopic code

(Date:7/9/2015)... , July 07, 2015 ... the addition of the "Biometrics for Banking; ... 2015-2020" report to their offering. ... contributor to this growth and the forecast is ... in revenue for companies involved in delivering biometric ...
(Date:7/9/2015)... 9, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced a new Match-in-Sensor™ ... hardware encapsulated fingerprint sensor and matching solution. ... literally off the grid, isolating fingerprint image ... the fingerprint sensor to provide ultimate protection ...
(Date:7/8/2015)... NEW YORK , July 8, 2015  BD ... announced BD & Guidepoint Mentor, a new ... to Guidepoint,s expert network services. BD ... technologies to improve healthcare delivery and outcomes and, with ... start-up entrepreneur will be able to directly engage with ...
Breaking Biology News(10 mins):Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 2Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 3BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 3
... 9, 2010 USDA Forest Service researchers found that ... habitats, is strong in the Sierra Nevada yellow-legged frog. ... climate and introduced non-native trout are negatively impacting the ... of its historic localities, and will further stress frogs ...
... in 1906, the German physician Paul Ehrlich coined the term ... medical treatment. Magic bullets, also called silver bullets, because ... supernatural creatures, remain the goal of drug development efforts today. ... Louis is currently working on a magic bullet for cancer, ...
... hydrosurgery system to help physicians better manage excessive bleeding during surgery., ... Oberdier, a Ph.D. candidate in biomedical engineering at ... clear excess blood and control bleeding during critical stages involving brain operations., ... "We are creating a device that will ...
Cached Biology News:Sierra Nevada yellow-legged frog's site fidelity may lead to further decline 2A golden bullet for cancer 2A golden bullet for cancer 3A golden bullet for cancer 4A golden bullet for cancer 5
(Date:7/29/2015)... +14% CER / 20% of sales) led the regional performance in the second ... well as solid contributions from Korea, India and ... East / Africa (Q2 2015: +3% CER ... Turkey and the United Kingdom . The ... HPV sales, on demand across all customer classes. The top seven emerging markets ...
(Date:7/29/2015)... SAN FRANCISCO , July 29, 2015 /PRNewswire/ ... trialling mobile molecular testing for applications in food ... Ubiquitome,s hand-held, battery powered real-time PCR device, the ... the farm right through to the supermarket shelf ... world. This includes involvement in animal disease control ...
(Date:7/29/2015)... ... 29, 2015 , ... Brady (NYSE:BRC), a global leader in ... To align chemical container labeling with OSHA’s updated Hazard Communication (HazCom) Standard and ... example of an accurate label, and pictogram uses and meanings. , “With changes ...
(Date:7/29/2015)... SAN DIEGO , July 29, 2015  Pfenex ... quarter 2015 financial results will be released on Thursday, ... 8:30 am Eastern Time, Pfenex management will host a ... a business update.  A press release outlining the financial ... to the call. Please call 1-866-376-8058 (US) ...
Breaking Biology Technology:QIAGEN Reports Results for Second Quarter and First Half of 2015 2QIAGEN Reports Results for Second Quarter and First Half of 2015 3QIAGEN Reports Results for Second Quarter and First Half of 2015 4QIAGEN Reports Results for Second Quarter and First Half of 2015 5QIAGEN Reports Results for Second Quarter and First Half of 2015 6QIAGEN Reports Results for Second Quarter and First Half of 2015 7QIAGEN Reports Results for Second Quarter and First Half of 2015 8QIAGEN Reports Results for Second Quarter and First Half of 2015 9QIAGEN Reports Results for Second Quarter and First Half of 2015 10AsureQuality and Ubiquitome Partner on Applications for Mobile Molecular Food Safety Testing 2Brady Announces a New GHS Label Guide 2Pfenex To Report Second Quarter 2015 Results and Provide Business Update on Thursday, August 13, 2015 2
... Wisconsin-born leader in the World Health Organization has laid ... and develop an antidote to nicotine addiction, and the ... , ,Tom Loftus, the former U.S. ambassador to Norway ... a sobering global perspective to last weeks Wisconsin Life ...
... Madison, Wis. - Companies looking to thrive in an ... Wisconsin Public Radio reports on one rather unusual method: speed-networking, ... Technology Network... Listen to this story now using RealPlayer ... its the fast that eat the slow. That phrase was ...
... CHICAGO This column isnt just for Midwestern technology job seekers. ... so hard on job seekers here? Because so many of us ... More than that, it's because theres so much to say on ... know. So many angles to try. And, for better or worse, ...
Cached Biology Technology:AIDS and tobacco are worldwide killers: Is bioscience doing enough to stop them? 2Looking to be Competitive? Try Speed Networking 2Its Your Midwest Technology Wake, Stupid 2Its Your Midwest Technology Wake, Stupid 3
... 5 Fluorescein 6-Fam, Hex, Tet ... Fluorescein Tamra Black Hole Quenchers ... Hex, Tet Tamra, Joe 3 ... Institute, New York Double labelled probes are ...
... The flexible and easy ... used to control all members ... family. It features a clear ... visual assay setup, user-friendly and ...
... Recombinant Enterokinase (rEK) is a highly ... bovine enterokinase, a serine protease which recognizes ... enzyme (AspAspAspAspLys?) and has similar enzymatic activity ... coli and purified to yield the highest ...
Roll of Mesh 5m x 25cm...
Biology Products: