Navigation Links
BGSU biologist trying to crack microscopic code

Dr. Ray Larsen is trying to learn a second language. The Bowling Green State University biologist wants to crack the communication code of proteins, especially the ones whose "talking" aids and abets disease.

"Proteins interact; they 'talk' to each other," the associate professor says. "It's how they know what to do, and it's how most of the things that need to happen for living organisms get done."

Over the past three years he has received $300,000 in funding from the National Science Foundation for his research.

What talking proteins have to do with infectious disease is a story that unfolds in the submicroscopic world of molecular biology. It starts with bacteria, which are cloaked by an outer membrane--a defensive barrier against the harsh elements of their environment, whether toxins in nature or the protective antibodies of an infected host. Specific proteins interact to support this shield, and knowing how they communicate would provide a key to disabling it, Larsen says.

Once communication questions are answered, a goal is to develop drugs to break the barrier, rendering the bacteria more susceptible to the human body's natural defenses--antibodies--as well as certain antibiotics, he points out.

While keeping potential dangers out, the outer membrane must also be porous enough to allow nutrients in, he continues. As an analogy, he cites a house with a yard and a chain-link fence that "keeps the dogs out of the roses but lets the butterflies through."

A short distance separates the outer membrane and the rest of the organism. How the bacteria maintain their barrier when it's physically removed from the rest of the cell, and thus separated from its energy source, is where his interest lies.

"The barrier is not self-sustaining, so the bacteria must export energy to it," says Larsen, referring to protein systems that take cellular energy and use it to support the outer membrane. "It's kind of like get
'"/>

Source:Bowling Green State University


Page: 1 2 3

Related biology news :

1. Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
2. GeneNotes - A novel information management software for biologists
3. NYU biologists map out early stages of embryo formation
4. FSU biologists describe key role of signal-transcribing gene during cell cycle
5. Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
6. High-tech tags on marine animals yield valuable data for biologists and oceanographers
7. UCSD biologists find new evidence for one-way evolution
8. FSU biologist says new dinosaur is oldest cousin of Tyrannosaurus rex
9. UC San Diego biologists solve plant growth hormone enigma
10. FSU biologists uncover mechanisms that shape cells for better or worse
11. NYU biologists identify gene that coordinates two cellular processes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: BGSU biologist trying crack microscopic code

(Date:8/28/2014)... significant health risk to people with asthma according to a ... Clinical Immunology . , By critically reviewing the findings from ... that the presence of several types of mould can lead ... the likelihood of developing the condition. , The research has ... Medical School and is the first time all of the ...
(Date:8/28/2014)... California, and Alaska totaled 515 million board feet in ... of more than 10 percent compared to the first ... Research Station reported today. During this same period, West ... million board feet. , The total value of these ... $390 million in the same quarter, while the total ...
(Date:8/28/2014)... Ludwig-Maximilians-Universitaet (LMU) in Munich have assigned a number ... predatory arthropods. These animals lived in shallow marine ... forms found in Jurassic strata. , Before ... marine habitat and were fossilized some 435 million ... of the Silurian seas although they were ...
Breaking Biology News(10 mins):Indoor mold poses health risk to asthma sufferers 2West coast log exports up, lumber exports down in second quarter of 2014 2Paleontology: Oldest representative of a weird arthropod group 2
... become after being exposed to a specialized electrical field ... or a stage of cancer already invading other parts ... electrical process and found cells that expanded the most ... has spread beyond its point of origin. The technique ...
... German . Within the last few years ... has been increased considerably. A worthwhile effort as, after ... and safe methods of transport checks are offered by terahertz ... however, it has to be measured quantitatively, so that damage ...
... the worlds of law, geography, economics, public health ... College London) on Friday September 19th to examine ... locally-rooted champions for global sustainability, reaching out to ... change. The symposium, which is called: "The Sustainable ...
Cached Biology News:Expanding cell girth indicates seriousness of breast cancer 2Checking people at airports -- with terahertz radiation 2Universities develop a more sustainable future 2
(Date:8/28/2014)... Vt. (PRWEB) August 28, 2014 ... testing around the world is available from Strategic ... diagnostics companies. “ Industrial Microbiology Market Review, Fourth ... Industrial Market ” (IMMR—4) tracks and compares microbiology ... in North America, Europe and Asia, and forecasts ...
(Date:8/28/2014)... Supplementing their complete line of ... Eppendorf Safe Lock Centrifuge Tubes . This ... quality tubes at an affordable price. Eppendorf Safe ... chemical, medical, pharmaceutical, and life science research and ... able to afford Eppendorf products. , Eppendorf is ...
(Date:8/27/2014)... 27, 2014 Green & Grow Inc. ... B funding and secured Otter Capital as a significant ... accelerate commercialization of GGI’s Agriplier™ technology, building on recent ... , “Since our first meeting, we have been impressed ... product space,” said Alan Sobba, President and CEO of ...
(Date:8/27/2014)... , Aug. 27, 2014 Reportlinker.com ... is available in its catalogue: ... http://www.reportlinker.com/p02316661/Global-Biodegradable-Packaging-Materials-Market-2014-2018.html ... materials that are readily decomposed by the ... conventional non-degradable packaging in terms of raw ...
Breaking Biology Technology:2 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 2Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 3Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 2Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 3Global Biodegradable Packaging Materials Market 2014-2018 2Global Biodegradable Packaging Materials Market 2014-2018 3Global Biodegradable Packaging Materials Market 2014-2018 4Global Biodegradable Packaging Materials Market 2014-2018 5Global Biodegradable Packaging Materials Market 2014-2018 6Global Biodegradable Packaging Materials Market 2014-2018 7
... Pa. , Aug. 2 Tengion Inc. (Nasdaq: ... Brian Davis to the position of Chief Financial Officer.  Mr. Davis ... company using enzymatic technologies to develop improved protein therapeutics. At its peak, ... three sites.  , , , ...
... 15,000 of them. A Northwestern University research team ... with tiny beams of light using an innovative nanofabrication ... new method, which could do for nanofabrication what the ... will be published Aug. 1 by the journal ...
...  The European Commission announced that it has granted import, ... developed by DuPont (NYSE: ... AgroSciences LLC , a wholly owned subsidiary of   The ... insect protection and the Herculex® RW trait stack (also known ...
Cached Biology Technology:Tengion Appoints A. Brian Davis Chief Financial Officer 215,000 beams of light 215,000 beams of light 3European Union Approves Maize with Herculex® I/Herculex® RW and Herculex® RW/ Herculex® I/Roundup Ready® Corn 2 Trait Stacks for Import, Food, Feed & Processing 2European Union Approves Maize with Herculex® I/Herculex® RW and Herculex® RW/ Herculex® I/Roundup Ready® Corn 2 Trait Stacks for Import, Food, Feed & Processing 3European Union Approves Maize with Herculex® I/Herculex® RW and Herculex® RW/ Herculex® I/Roundup Ready® Corn 2 Trait Stacks for Import, Food, Feed & Processing 4
"BioTracker 6X Bromophenol Blue Tracking Dye is composed of 60% St DI H2O, 30% Glycerol, 10% 10XTE, 0.25% BPB Dye and 0.85% SDS....
Request Info...
Agarose, low melting/gelling temperature, high MW separation (>1000 bp), 25 g. Suitable for enzymatic modifications. Nuclease-free.Gel point: 24-30 C, EEO (-mr): 300 gm/cm2. Category: Nucleotides &...
Request Info...
Biology Products: