Navigation Links
BGSU biologist trying to crack microscopic code

Dr. Ray Larsen is trying to learn a second language. The Bowling Green State University biologist wants to crack the communication code of proteins, especially the ones whose "talking" aids and abets disease.

"Proteins interact; they 'talk' to each other," the associate professor says. "It's how they know what to do, and it's how most of the things that need to happen for living organisms get done."

Over the past three years he has received $300,000 in funding from the National Science Foundation for his research.

What talking proteins have to do with infectious disease is a story that unfolds in the submicroscopic world of molecular biology. It starts with bacteria, which are cloaked by an outer membrane--a defensive barrier against the harsh elements of their environment, whether toxins in nature or the protective antibodies of an infected host. Specific proteins interact to support this shield, and knowing how they communicate would provide a key to disabling it, Larsen says.

Once communication questions are answered, a goal is to develop drugs to break the barrier, rendering the bacteria more susceptible to the human body's natural defenses--antibodies--as well as certain antibiotics, he points out.

While keeping potential dangers out, the outer membrane must also be porous enough to allow nutrients in, he continues. As an analogy, he cites a house with a yard and a chain-link fence that "keeps the dogs out of the roses but lets the butterflies through."

A short distance separates the outer membrane and the rest of the organism. How the bacteria maintain their barrier when it's physically removed from the rest of the cell, and thus separated from its energy source, is where his interest lies.

"The barrier is not self-sustaining, so the bacteria must export energy to it," says Larsen, referring to protein systems that take cellular energy and use it to support the outer membrane. "It's kind of like get
'"/>

Source:Bowling Green State University


Page: 1 2 3

Related biology news :

1. Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
2. GeneNotes - A novel information management software for biologists
3. NYU biologists map out early stages of embryo formation
4. FSU biologists describe key role of signal-transcribing gene during cell cycle
5. Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
6. High-tech tags on marine animals yield valuable data for biologists and oceanographers
7. UCSD biologists find new evidence for one-way evolution
8. FSU biologist says new dinosaur is oldest cousin of Tyrannosaurus rex
9. UC San Diego biologists solve plant growth hormone enigma
10. FSU biologists uncover mechanisms that shape cells for better or worse
11. NYU biologists identify gene that coordinates two cellular processes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: BGSU biologist trying crack microscopic code

(Date:4/27/2015)... 2015  For more than four decades, AUVSI,s ... the premier worldwide event for the unmanned land, sea, ... event for any local, national, or trade news organization ... markets and current applications of unmanned technologies. The conference ... $48 billion industry, and how it will soon impact ...
(Date:4/27/2015)... LAUDERDALE, Fla. , Apr. 27, 2015 ... of access control and security systems is pleased to ... the company as a consultant and member of its ... is widely known as a thought leader in ... Distance Learning Technology Group, and has published studies and ...
(Date:4/20/2015)... 20, 2015 Huntington Memorial Hospital is the ... a new miniaturized, wireless monitoring sensor to manage heart ... and only FDA-approved heart failure monitoring device that has ... by physicians to manage heart failure. The ... in the pulmonary artery (PA) during a non-surgical procedure ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3
... and Germany has intensified. This was highlighted by Professor ... Research Foundation), during a visit to India taking him ... on Nov. 3 and 4, 2011. "Cooperation ... dimension," said the DFG President in a meeting with ...
... (Nov. 9, 2011; 12:50 p.m.) Late breaking clinical ... antiplatelet, showed patients can be "bridged" from the ... until they undergo cardiac surgery. Study results demonstrated ... be associated with a low risk of thrombotic events, ...
... to lose weight won,t need to track their daily ... created at the University of Pittsburgh. eButton -- a ... contains a miniature camera, accelerometer, GPS, and other sensors ... the need for daily self-reporting. The eButton prototype was ...
Cached Biology News:Scientific collaboration between India and Germany reaches new dimension 2Scripps Health/the Medicines Company announce late breaking BRIDGE trial results presented at TCT 2Pitt researchers develop eButton, an easier way to monitor food intake, exercise, and lifestyle 2
(Date:5/22/2015)... According to a new market ... Gel Electrophoresis, Agarose & Polyacrylamide Gel, Capillary Electrophoresis, Isoelectric ... & by End User - Global Forecast to 2020", ... reach around $1.98 Billion by 2020 with a CAGR ... Browse 226 ma rket data ...
(Date:5/21/2015)... (PRWEB) May 21, 2015 Seventh Wave ... safety and efficacy of pharmaceutical products and medical devices, ... Heights, MO 63043, a 50,000 sq. ft. building more ... to enable strategic growth. Facility renovations will begin immediately ... new space will occur in September. , “We ...
(Date:5/21/2015)... , May 21, 2015  The EveryLife ... Hatch (R-UT) and Amy Klobuchar ... Now Accelerating Cures & Treatments, or OPEN ACT. ... disease patient advocacy organizations, this bipartisan legislation promises ... affordable medicines to rare disease patients by incentivizing ...
(Date:5/21/2015)... SURPRISE, ARIZ. (PRWEB) May 21, 2015 ... E. Webb Medical Center (BDWMC), Sun Health Foundation funded ... medical center’s new inpatient pharmacy with the most up-to-date ... to open June 2. The pharmacy's 45 staff members ... much larger 4,895-square-foot space in the coming days. ...
Breaking Biology Technology:Electrophoresis Market Worth $1.98 Billion by 2020 2Electrophoresis Market Worth $1.98 Billion by 2020 3Electrophoresis Market Worth $1.98 Billion by 2020 4Seventh Wave Laboratories Purchases Building for Expansion, Upcoming Move 2Seventh Wave Laboratories Purchases Building for Expansion, Upcoming Move 3Advocates Cheer Senate Leaders for Introducing Bipartisan Bill to Increase Number of Rare Disease Treatments 2Sun Health Foundation Provides $3.25M to Expand, Relocate Banner Del E. Webb Medical Center Pharmacy 2Sun Health Foundation Provides $3.25M to Expand, Relocate Banner Del E. Webb Medical Center Pharmacy 3
... and Waukesha counties signed an agreement Monday to cooperate ... Center for Advanced Technology and Innovation (CATI) . The ... the number of high-paying technology jobs at small- and ... area innovations in technology from draining out of the ...
... Friday morning the formation of a new bioenergy consortium ... Industry, composed of various experts in both the public ... of Agriculture and Natural Resources and the Administration Department's ... do to advance biobased alternative energy solutions in Wisconsin. ...
... In 1996, the last time the Biotechnology Industry Organization ... A decade later, BIO expects at least 18,000 convention-goers to ... as city officials here may claim its all about their ... the BIO 2005 crowd says much more about the growth ...
Cached Biology Technology:Southeastern Wisconsin Technology Collaboration 2Southeastern Wisconsin Technology Collaboration 3Southeastern Wisconsin Technology Collaboration 4Doyle announces biobased energy consortium 2Doyle announces biobased energy consortium 3Wisconsin can shine in the competitive biotech world, even among the giants 2Wisconsin can shine in the competitive biotech world, even among the giants 3