Navigation Links
Agent slows aging in mice

Aspirin didn’t pan out. Neither did two other potential anti-aging agents. But a synthetic derivative of a pungent desert shrub is now a front- runner in ongoing animal experiments to find out if certain chemicals, known to inhibit inflammation, cancer and other destructive processes, can boost the odds of living longer.

Today at the annual meeting of the American Aging Association, University of Michigan scientist Richard A. Miller reports early results from a mouse study his lab and two others are conducting for the National Institute on Aging. The study, now in its fourth year, will test as many as two dozen possible anti-aging agents in animals in the next five years. The other centers are the University of Texas Health Science Center in San Antonio, Texas, and the Jackson Laboratory in Bar Harbor, Maine.

The scientists were surprised to find so quickly that one agent showed promise: NDGA, a compound derived from creosote bushes. These common North American desert shrubs have been traditionally used by Native Americans as healing remedies.

The preliminary results, to be published in August in the journal Aging Cell, show that male mice fed a normal diet and NDGA so far have survived in significantly greater numbers than mice on a normal diet. Scientists measured the difference at a point called median lifespan, when half the control mice had died of natural causes associated with aging.

“This is the first time to my knowledge when an agent has been shown to extend median life span in three laboratories,” says Miller, professor of pathology at the U-M Medical School and associate director of the U-M Geriatrics Center. Miller is also a research scientist at the Ann Arbor VA Medical Center.

No significant difference occurred in female mice. The scientists can’t explain why at this point. “We don’t know how NDGA is having its effect on survival in this first analysis,” Miller says.

“It may be that the f
'"/>

Source:University of Michigan Health System


Page: 1 2

Related biology news :

1. Cancer drug slows poxvirus in mice
2. Stress substantially slows human bodys ability to heal
3. Cell therapy slows progression of an inherited neurological disease; Improves motor skills in mice
4. Diabetes slows nerve recovery after heart transplant
5. Protein found that slows hepatitis C growth in liver cells
6. Imaging Lymph Nodes with Nanoparticles
7. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
8. Special Imaging Study Shows Failing Hearts Are Energy Starved
9. How the environment could be damaging mens reproductive health
10. Human Cells Filmed Instantly Messaging for First Time
11. Duke engineers develop new 3-D cardiac imaging probe
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Agent slows aging mice

(Date:8/20/2015)... 20, 2015 The wearable technology market ... active and healthy. However, wearable technology has the ... to help improve diagnostic capabilities and therapeutic outcomes. ... Wearable Technologies Conference 2015 , where ... wearables in healthcare.    "Over the ...
(Date:8/20/2015)... CT ., Aug. 20, 2015 NXT-ID, ... a biometric authentication company focused on the growing mobile ... announces it has joined The Smart Card Alliance and ... Smart Card Alliance and the Smart Card Alliance Latin ... visibility to industry peers and thought leaders promoting adoption ...
(Date:8/18/2015)... , Aug. 18, 2015  Navitas ... key contributor to the Submission Content Management ... IRISS, a non-profit forum. Dedicated to the Implementation ... a neutral platform for industry, vendors, health ... information and work towards a standard method ...
Breaking Biology News(10 mins):Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 2NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 4Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3
... (Atlanta, Ga. August 20, 2008) Today, the U.S. Environmental ... grant to the University of Kentucky (UK) to investigate how ... enter the brain. This is the largest EPA Science ... of Kentucky as well as the largest single grant ever ...
... (Aug. 20, 2008) The genetic code of a simple saltwater ... function in humans and other species. A study published this ... code of Trichoplax , a simple saltwater creature that one ... aquarium. "We,re trying to identify, in the Trichoplax , ...
... heart attacks. But to do that they have to provide ... a team led by William Maisel at Harvard Medical School ... modify wireless communications from a pacemaker ( New Scientist, ... monitor and adjust the implanted device, but a malicious hacker ...
Cached Biology News:$2M grant awarded to University of Kentucky for research on nanoparticles and human health 2Genome of saltwater creature could aid understanding of gene grouping 2How to stop a new type of heart attack 2
(Date:9/4/2015)... Francisco, CA (PRWEB) , ... September 04, 2015 ... ... the delivery of product safety and pharmacovigilance services and software tools to pharmaceutical ... application, PRIMO Mobile by Allergan Japan. PRIMO Mobile is a mobile data intake ...
(Date:9/3/2015)... Texas , Sept. 3, 2015  Vermillion, Inc. ... on gynecologic disease, today announced that Herbert Fritsche ... subsidiary, ASPiRA LABS, is the recipient of the 2015 ... and Biomarkers (ISOBM) for outstanding contributions to the field ... the award on October 5 th in Zakopane, ...
(Date:9/3/2015)... Santa Clara, CA (PRWEB) , ... September 03, 2015 , ... ... 3D printing and additive manufacturing on Sept. 17, 2015 at 9am PST. The webinar ... understanding and application. More popularly known as 3D printing, additive manufacturing is a broad ...
(Date:9/2/2015)... , Sept. 2, 2015 ... announced the addition of Jain PharmaBiotech,s new ... to their offering. ... pharmaceutical and biotechnology industries is anticipated. Nanotechnology ... drug development - from formulations for optimal ...
Breaking Biology Technology:November Research Group’s PRIMO Mobile Goes Live at Allergan Japan 2Vermillion Announces Dr. Herbert Fritsche as Recipient of the 2015 Abbott Award from the International Society of Oncology and Biomarkers 2Park Systems Announces Webinar on 3D Printing and Additive Manufacturing for Nano-Scientists, Researchers in Nanotechnology and Engineers 2Park Systems Announces Webinar on 3D Printing and Additive Manufacturing for Nano-Scientists, Researchers in Nanotechnology and Engineers 3Park Systems Announces Webinar on 3D Printing and Additive Manufacturing for Nano-Scientists, Researchers in Nanotechnology and Engineers 4Global Nanobiotechnology Applications, Markets and Companies Report 2015-2024 2Global Nanobiotechnology Applications, Markets and Companies Report 2015-2024 3
... ... grows, albeit more slowly than in 2009, changes to the pharmaceutical landscape could mean the ... ... of a confusing month in terms of the employment situation. Overall, the Bureau of Labor ...
... A cheap and simple way of making vaccines stable ... to work by scientists at Oxford University. The ... removes the need for fridges, freezers and associated health ... - particularly in the developing world where infectious diseases ...
... , MILFORD, Mass. ... Waters Corporation and DAISO CO., LTD. jointly ... agreement to globally market and supply DAISOGEL™ bulk packing ... both organizations will aid pharmaceutical and biopharmaceutical companies as ...
Cached Biology Technology:The MedZilla Report for February 2010 - Health Care Growth Slows; Big Pharma May Cut Thousands as Sales Landscape Changes 2The MedZilla Report for February 2010 - Health Care Growth Slows; Big Pharma May Cut Thousands as Sales Landscape Changes 3The MedZilla Report for February 2010 - Health Care Growth Slows; Big Pharma May Cut Thousands as Sales Landscape Changes 4New method makes vaccines stable at tropical temperatures 2New method makes vaccines stable at tropical temperatures 3Waters and DAISO Sign Marketing Agreement for Bulk Process Chromatography Media 2Waters and DAISO Sign Marketing Agreement for Bulk Process Chromatography Media 3
...
X-Gal, 100 mg. 5-Bromo-4-chloro-3-indolyl-b-d-galactoside.Histochemical substrate for b-galactosidase, used in blue/white screening.Store at -20 C. Protect from moisture. Category: Nucleotides & Enzy...
...
RayBio L Series 507: RayBio Label-based Antibody Array I (2 membranes) Class: Antibody Array Products Product Group: Antibody Array...
Biology Products: