Navigation Links
APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal

months, repeating this process and then passing the information on to their successors. The interaction between T cells and dendritic cells in the lymph node changes over time, von Andrian said.

"It's nice that the T cell learns to recognize the antigen, but that doesn't get rid of the microbe that has entered the body," von Andrian said. He traced the path of the educated T cells leaving the lymph node, when they become known as effector cells. In addition, von Andrian addressed how these T cells kill those cells they identified as harboring a pathogen without going on a rampage and annihilating everything in sight.

"There must be a control mechanism that can keep these cytotoxic cells in check," von Andrian noted. The immune system does this by creating regulatory T cells to control the effector cells, he said. Previous research had shown that the regulatory T cells can also receive their education in the lymph node before proliferating and entering the blood stream.

May lead to vaccines

"The events I have described are at the heart of any vaccination," von Andrian said. Many pathogens take advantage of the lymph system to gain access to the body, he noted, including pathogens used in biological warfare, such as anthrax, or yersinia pestis, the agent that causes the plague.

Bubonic plague, for instance, starts with a flea that deposits a few bacteria, which travel via the lymphatic system to the lymph node and proliferate to huge numbers. One of the puzzles von Andrian has been working on, is how foreign invaders manage to proliferate in the very area, the lymph node, where the immune system is marshaling its troops.

"So understanding how these (foreign) cells survive in the lion's den of the lymph node might allow us to develop strategies to combat infections," von Andrian said. "Somehow, they do this without ringing the alarm bells. Possibly we could manipulate the process to ring the alarm bell for the immu
'"/>

Source:American Physiological Society


Page: 1 2 3 4 5

Related biology news :

1. Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
2. “Nano-scissors?laser shows precise surgical capability
3. Clam embryo study shows pollutant mixture adversely affects nerve cell development
4. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
5. Study shows nanoshells ideal as chemical nanosensors
6. Gene vaccine for Alzheimers disease shows promising results
7. Flocking together: Study shows how animal groups find their way
8. New drug shows promise as powerful anticancer agent
9. Loves all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
10. Test for early detection of prostate cancer shows promise
11. Mouse gene shows new mechanism behind cardiac infarction in man
Post Your Comments:
(Date:5/20/2015)... May 20, 2015 NXT-ID, Inc. (NASDAQ: ... wholly owned subsidiary, 3D-ID LLC, a company engaged in ... for the biometrics technology portion of the recently awarded ... the Department of the Army. 3D-ID LLC ... for government, law enforcement and security agencies. ...
(Date:5/19/2015)... May 19, 2015  Technology is rapidly advancing, outpacing ... in the cloud. Passwords and their management are soon ... and standards-based specifications such as those developed by the ... of passwords presents for BYOD, COPE, IoT, and mobile ... identity protocol. In response to the ...
(Date:5/18/2015)... Fingerprint Cards (FPC) has received an order for ... from one if its module partners. Deliveries are planned to ... the sensors will be used by smartphone manufacturers in ... amount to 740 MSEK to date. In addition to previously ... number of smaller orders not separately communicated amounting to more ...
Breaking Biology News(10 mins):NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 2HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2
... Atlantic right whale's future looks grim if the current ... professor of oceanography Douglas Nowacek and a group of ... co-authored a paper titled "North Atlantic Right Whales in ... the journal Science. , In it, Nowacek and his ...
... well-respected researcher who is now a chief of an immunology ... the boat in the past few years for the experts ... Matzinger has developed the "danger model," suggesting that the immune ... of a biological cell's death than with the introduction of ...
... new muscle complete with its own network of blood ... in a living mouse. The accomplishment is a first ... June 19 issue of Nature Biotechnology. , Lead researcher ... along with scientists from the Massachusetts Institute of Technology, ...
Cached Biology News:Scientists to mimic nature for newest cancer drugs 2Researchers seek to discover what really happens when a virus enters the body 2Researchers seek to discover what really happens when a virus enters the body 3New complete muscle grown in the lab 2
(Date:5/21/2015)... - SQI Diagnostics Inc. ("SQI" or the "Company") (TSX-V: ... commercializes proprietary technologies and products for advanced microarray diagnostics, ... second fiscal quarter ended March 31, 2015. ... business with our existing customers and to develop new ... of SQI. "The delivery of a fully automated sqidlite™ ...
(Date:5/21/2015)... 2015 Specialty Pharmacy Times has ... admitted to BPA Worldwide as a business publication ... audience data for Specialty Pharmacy Times based on ... becoming a member of BPA Worldwide, Specialty Pharmacy ... clients with the most reliable, unequaled data,” said ...
(Date:5/21/2015)... 21, 2015  Prima Biomed Ltd. (NASDAQ: PBMD ... to become a leader in the development of immunotherapeutic ... the final CVac data from the Phase II CAN-003 ... for a clinically meaningful improvement in Overall Survival ("OS") ... In the group of second remission patients ...
(Date:5/21/2015)... , May 21, 2015  The EveryLife ... Hatch (R-UT) and Amy Klobuchar ... Now Accelerating Cures & Treatments, or OPEN ACT. ... disease patient advocacy organizations, this bipartisan legislation promises ... affordable medicines to rare disease patients by incentivizing ...
Breaking Biology Technology:SQI Diagnostics Reports Second Quarter Financial Results 2SQI Diagnostics Reports Second Quarter Financial Results 3SQI Diagnostics Reports Second Quarter Financial Results 4SQI Diagnostics Reports Second Quarter Financial Results 5SQI Diagnostics Reports Second Quarter Financial Results 6SQI Diagnostics Reports Second Quarter Financial Results 7SQI Diagnostics Reports Second Quarter Financial Results 8Specialty Pharmacy Times Joins BPA Worldwide 2Correction Continues after Big Move - BrokerBank Securities, Inc. 2Advocates Cheer Senate Leaders for Introducing Bipartisan Bill to Increase Number of Rare Disease Treatments 2
... of Yeshiva University have shown for the first time ... common form of the disease) in an animal model. ... of Clinical Investigation. , Hemophilia A affects one in ... that can cause disability or death. It has, most ...
... to ... Broaden Product Portfolio, WAYNE, Pa., Feb. 14 Escalon ... second quarter and,six months ended December 31, 2007., For the ... Company,s Drew, Vascular and Escalon Digital Solutions (EMI),business units, which increased ...
... Calif., Feb. 14 Telik, Inc.,(Nasdaq: TELK ) ... held on Thursday, February 21, 2008 at 4:30 p.m. ... that day of the company,s,financial results for the fourth ... conference call will be accessible via Telik,s website at, ...
Cached Biology Technology:Transplanted cells may hold the key to curing hemophilia A, Einstein scientists report 2Escalon(R) Reports Second Quarter Fiscal 2008 Results 2Escalon(R) Reports Second Quarter Fiscal 2008 Results 3Escalon(R) Reports Second Quarter Fiscal 2008 Results 4Escalon(R) Reports Second Quarter Fiscal 2008 Results 5Escalon(R) Reports Second Quarter Fiscal 2008 Results 6Escalon(R) Reports Second Quarter Fiscal 2008 Results 7Escalon(R) Reports Second Quarter Fiscal 2008 Results 8
Fast, sensitive quantitation of Mouse IgM concentration....
Request Info...
... anti-rabbit IgG FITC is used as ... staining on tissues or culture cells ... in rabbits. It is highly recommended ... omitting the primary antibody, be included ...
1000X solution used for inducing CopyControl™ based vectors to high copy numbers...
Biology Products: