Navigation Links
A new approach to growing heart muscle

It looks, contracts and responds almost like natural heart muscle ?even though it was grown in the lab. And it brings scientists another step closer to the goal of creating replacement parts for damaged human hearts, or eventually growing an entirely new heart from just a spoonful of loose heart cells.

This week, University of Michigan researchers are reporting significant progress in growing bioengineered heart muscle, or BEHM, with organized cells, capable of generating pulsating forces and reacting to stimulation more like real muscle than ever before.

The three-dimensional tissue was grown using an innovative technique that is faster than others that have been tried in recent years, but still yields tissue with significantly better properties. The approach uses a fibrin gel to support rat cardiac cells temporarily, before the fibrin breaks down as the cells organize into tissue.

The U-M team details its achievement in a new paper published online in the Journal of Biomedical Materials Research Part A.

And while BEHM is still years away from use as a human heart treatment, or as a testing ground for new cardiovascular drugs, the U-M researchers say their results should help accelerate progress toward those goals. U-M is applying for patent protection on the development and is actively looking for a corporate partner to help bring the technology to market.

Ravi K. Birla, Ph.D., of the Artificial Heart Laboratory in U-M's Section of Cardiac Surgery and the U-M Cardiovascular Center, led the research team.

"Many different approaches to growing heart muscle tissue from cells are being tried around the world, and we're pursuing several avenues in our laboratory," says Birla. "But from these results we can say that utilizing a fibrin hydrogel yields a product that is ready within a few days, that spontaneously organizes and begins to contract with a significant and measurable force, and that responds appropriatel
'"/>

Source:University of Michigan Health System


Page: 1 2 3 4

Related biology news :

1. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
2. MSI releases moleculizer - a new approach to simulation of intracellular biochemical networks
3. Stopping smallpox in its tracks: A new anti-viral approach
4. Building a protein name dictionary from full text: a machine learning term extraction approach
5. Rensselaer researchers develop approach that predicts protein separation behavior
6. Huntingtons cure in flies lays groundwork for broader treatment approaches
7. Results of worlds first gene therapy trial for arthritis show approach safe, feasible
8. Vaginal gel may provide a new approach to HIV prevention
9. Clinical trial to test stem cell approach for children with brain injury
10. Study in Science holds promise for a new approach to drug therapy
11. U-M researchers take new approach to defeating Gram-negative bugs
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: new approach growing heart muscle

(Date:5/10/2015)... -- Fingerprint Cards (FPC) has received an order ... distributor World Peace Industrial Group (WPI), part of WPG Holdings. ... . Deliveries are planned to take place during Q3 ... in China . The order value of ... + 1 000 MSEK for 2015.   Jörgen Lantto, ...
(Date:5/6/2015)... May 6, 2015 LifeBEAM, a developer of ... producer, announced today that they will expand their partnership ... first bio-sensing cycling helmet and the first joint project ... new colors in order to give cyclists more style ... addition, LifeBEAM and Lazer announced their plan to release ...
(Date:4/27/2015)... , Apr. 27, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, ... to pre-order customers the first week of May, 2015 ... month of May. Gino Pereira ... milestone for the company as Wocket® enters the consumer ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 235 Million 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3
... $5 million National Science Foundation (NSF) grant to upgrade ... Owens Valley Solar Array (OVSA) http://www.ovsa.njit.edu/ ... is expected to help scientists better understand the nature ... the military. "Space weather incidents such as ...
... What:,Based on what we know about smoking, diet, ... estimate we could prevent approximately half of all ... Association for Cancer Research will host its Ninth ... Research at the Pennsylvania Convention Center, located in ...
... Bad Hofgastein, 6 October 2010 -- European patients are in ... medically assisted reproduction (MAR) treatment, experts from the European Society ... European Health Forum Gastein (EHFG). The EHFG is ... EU. This year it has attracted about 600 decision-makers from ...
Cached Biology News:$5 million NSF grant will upgrade and expand NJIT radio telescope array 2$5 million NSF grant will upgrade and expand NJIT radio telescope array 3Reproductive health: Checkerboard of infertility treatment in Europe 2Reproductive health: Checkerboard of infertility treatment in Europe 3
(Date:5/21/2015)... TORONTO , May 21, 2015 /PRNewswire/ - SQI ... SQIDF),a life sciences company that develops and commercializes proprietary ... its financial and operational results for the second fiscal ... the quarter the Company continued to advance business with ... Andrew Morris , President and CEO of SQI. ...
(Date:5/21/2015)... St. Louis, MO (PRWEB) May 21, 2015 ... that assesses the safety and efficacy of pharmaceutical products ... Access Drive Maryland Heights, MO 63043, a 50,000 sq. ... their current location, to enable strategic growth. Facility renovations ... offices to the new space will occur in September. ...
(Date:5/21/2015)... Specialty Pharmacy Times has completed ... to BPA Worldwide as a business publication member. ... data for Specialty Pharmacy Times based on business/distribution, ... a member of BPA Worldwide, Specialty Pharmacy Times ... with the most reliable, unequaled data,” said Chris ...
(Date:5/21/2015)...  Susan Hedstrom, Executive Director of the Foundation ... to supporting research to advance the understanding and ... FPWR has received the organization,s largest donation to ... $1 million in support of the organization,s research ... "Our gift signifies our tremendous trust ...
Breaking Biology Technology:SQI Diagnostics Reports Second Quarter Financial Results 2SQI Diagnostics Reports Second Quarter Financial Results 3SQI Diagnostics Reports Second Quarter Financial Results 4SQI Diagnostics Reports Second Quarter Financial Results 5SQI Diagnostics Reports Second Quarter Financial Results 6SQI Diagnostics Reports Second Quarter Financial Results 7SQI Diagnostics Reports Second Quarter Financial Results 8Seventh Wave Laboratories Purchases Building for Expansion, Upcoming Move 2Seventh Wave Laboratories Purchases Building for Expansion, Upcoming Move 3Specialty Pharmacy Times Joins BPA Worldwide 2The Foundation for Prader-Willi Research Receives $1M Contribution in Support of Clinical Initiatives 2
... Company,s Move Driven by Commitment of Governor and ... with Leading Stem Cell Researcher, EWING, N.J., May 1 ... Coast operations in Ewing, N.J., The move, which was ... New Jersey Economic Development Authority,puts StemCyte,s executives in close proximity ...
... Representatives Unveil State-of-the-Art Facility ... ... Officials from Novavax,Inc. (Nasdaq: NVAX ), the State of ... state-of-the-art vaccine production,facility at the company,s headquarters in Rockville, Maryland. ...
... Halozyme Therapeutics, Inc.,(Nasdaq: HALO ), a biopharmaceutical ... today announced that it will,release financial results for ... close on Thursday, May 8, 2008., Jonathan ... Frost,PhD, Vice President and Chief Scientific Officer, Robert ...
Cached Biology Technology:StemCyte Locates East Coast Operations in New Jersey 2Novavax Opens Its First U.S. Vaccine Plant 2Novavax Opens Its First U.S. Vaccine Plant 3Novavax Opens Its First U.S. Vaccine Plant 4Halozyme Therapeutics to Hold Pipeline Update Conference Call on May 9 2
... New Concept in Microarrays: Biomedical Photometrics Inc. ... GmbH (Jena, Germany) have collaborated to develop ... ArrayTube System. The DNAscope AT is ... new DNAscope AT automatically reads up to ...
Complement factor B (human)...
Best pricing for 100mg-1.0g scales. Phosphopeptides are our specialty....
... Capillary Electrophoresis Running Buffer was designed to ... demands of todays sequencing labs. As a ... to the gel-based sequencing community Sigma has ... to meet your buffer needs. Scientists at ...
Biology Products: