Navigation Links
Zebrafish research shows how dietary fat regulates cholesterol absorption
Date:6/22/2012

MADISON, WI June 22, 2012 Buttery shrimp. Fried eggs. Burgers and fries. New research suggests there may be a biological reason why fatty and cholesterol-rich foods are so appealing together.

It has been known for more than 40 years that dietary fat promotes cholesterol uptake, but fundamental aspects of that process remain poorly understood. James Walters, Ph.D., and his colleagues at the Carnegie Institution for Science are using zebrafish to better understand the cellular mechanisms of cholesterol processing and have discovered a surprising link between dietary fat and cholesterol absorption.

"One reason these questions remain unknown is because of the difficulty of studying such a complex biological system as the intestine," which in addition to multiple cell types also includes a diverse array of enzymes, mucus, and symbiotic bacteria, he said in a June 20 presentation at the ongoing 2012 International Zebrafish Development and Genetics Conference in Madison, Wisconsin.

As a postdoctoral fellow in Dr. Steven Farber's lab at the Carnegie Institution for Science, in Baltimore, Maryland, Dr. Walters turned to young zebrafish, which provide a biologically complete and scientifically accessible system for studying the workings of the gut.

"Because the larval zebrafish are optically clear, we can visualize fat transport and processing by looking right through their body wall into the intestine where the action is," Dr. Walters said.

He developed a way to feed zebrafish a diet high in lipids (e.g., fat and cholesterol) or high in protein and low in lipids. He accomplished this by turning to the chicken egg, whipping fish water with the yolk for a high-lipid diet and the egg white as a high-protein diet. Before feeding these diets, fluorescently tagged cholesterol or fatty acid was added, enabling the microscopic viewing of how lipids are absorbed and processed by the intestinal cells.

Dr. Walters found th
'/>"/>

Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-351-0896
Genetics Society of America
Source:Eurekalert

Page: 1 2

Related biology news :

1. Versatility of zebrafish research highlighted at international conference
2. Environmental estrogens affect early developmental activity in zebrafish
3. Zebrafish could hold the key to understanding psychiatric disorders
4. Better housing conditions for zebrafish could improve research results
5. Notre Dame establishes professorships in adult stem cell research
6. Research: Many programs to help diabetics manage their health do work
7. Autism Speaks awards nearly $2.9 million to fund autism research
8. Researchers advance biometric security
9. University of Tennessee professor receives funding for clean coal research
10. Research could help track stem cells in the body
11. Argonne researchers receive 4 R&D 100 awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/5/2015)... , August 5, 2015 According ... Access Management Market by Software, Services, Vertical (BFSI, Airport, IT ... Geography - Global Forecast to 2020", published by MarketsandMarkets, ... Market globally into various segments. The global PIAM Market ... to $546.2 Million by 2019, at a CAGR of ...
(Date:8/4/2015)... , Aug. 04, 2015 ... ) has announced the addition of the ... Software, and Service), Sub-Segment (Computer Forensics, Network ... Tool Types, Service, Vertical and Region - ... their offering. By Component (Hardware, ...
(Date:7/31/2015)... juli 2015 Den 10. internationale konference om ... den 22. - 25. oktober i Shenzhen ... 10-års fødselsdag i år. Siden starten i 2006 er ... på ,omik,-feltet, og er en af de mest dynamiske, ... fokuserer på nylige gennembrud og fremskridt inden for ,omik,-forskning, ...
Breaking Biology News(10 mins):Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2
... Scientists have been hard at work harnessing the power ... Now, Biodesign Institute at Arizona State University researcher Dr. ... for enhancing the efficiency of clean energy production by ... MXCs are able to use bacterial respiration as a ...
... Earth sciences department at Clemson University has received a ... Commission (NRC) to help recruit and retain younger faculty ... U.S. universities to receive the faculty-development grants, which are ... expand the work force in nuclear safety and nuclear-related ...
... Inconspicuous "little brown balls" in the ocean have helped settle ... algae responsible for toxic red tides, according to a new ... article published this week in the Proceedings of the ... Patrick Keeling describes the genome of Chromera and its role ...
Cached Biology News:Microbe power as a green means to hydrogen production 2Microbe power as a green means to hydrogen production 3$400,000 NRC grant to develop nuclear engineering faculty at Clemson 2'Little brown balls' tie malaria and algae to common ancestor: UBC research 2
(Date:9/2/2015)... SYDNEY , Sept. 2, 2015 Australian ... won a prestigious Australian science prize recognising ,outstanding, science ... on track to globally launch a novel prostate cancer ... of a high level consortium taking out the peer-reviewed ... Interdisciplinary Scientific Research. This prize is ...
(Date:9/2/2015)... , September 2, 2015 ... BOLT) ("BioLight" or the "Company"), a firm that ... ophthalmology and cancer diagnostics, announced today that presentations ... glaucoma will be delivered at the Ophthalmology Futures ... European Society of Cataract & Refractive Surgeons ("ESCRS"), ...
(Date:9/2/2015)... ... September 02, 2015 , ... Advancing in medical ... From vital sign monitoring in ICU to 3D skull printing analysis for Neurosurgery, ... real-time clinical decisions with simultaneous access to high precision medical images and electronic ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... equipment, to creating professional commercial video content, to analysis of athletic performance. Producing ... events that go by too quickly to process with the naked eye. ...
Breaking Biology Technology:Prostate Cancer Company Minomic Wins Prestigious Eureka Science Prize 2Prostate Cancer Company Minomic Wins Prestigious Eureka Science Prize 3Presentations to Highlight BioLight's IOPtiMate[TM] System at Upcoming European Ophthalmology Conferences 2Presentations to Highlight BioLight's IOPtiMate[TM] System at Upcoming European Ophthalmology Conferences 3Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 2Surgical Workstation Powered by 6th Gen. Intel® Core™ Skylake Processors 3Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 2Fastec Introduces the Quad-HD TS5-Q High-Speed Camera 3
... be a challenge for some people because they either dont ... People have their own perceptions about the value of networking ... is only important when a need arises (such as a ... attitude fail to realize that networking is a process over ...
... is the technology consultant to the vice president of engineering ... he's an entrepreneur. , ,Polczynski's two-person business, M and ... "My take out of this is very soft," he said. ... global e-commerce micro-business has taught Polczynski a great deal about ...
... book, Islands in the Clickstream is a collection ... be reprinting excerpts from selected chapters of Islands in the ... an excerpt from chapter four, Hacking and the Passion for ... writings. , , Hactivism and Soul Power , ...
Cached Biology Technology:Dispelling the top five myths about attending networking events 2Dispelling the top five myths about attending networking events 3Dispelling the top five myths about attending networking events 4Irish flute passion drives e-commerce spirit for Eaton techie 2Irish flute passion drives e-commerce spirit for Eaton techie 3Islands in the Clickstream: Hactivism and Soul Power 2Islands in the Clickstream: Hactivism and Soul Power 3Islands in the Clickstream: Hactivism and Soul Power 4
Many mammalian cell types and experimental situations create challenges for standard transfection experiments. The ViraPower Lentiviral Expression System overcomes these challenges with efficient...
Many mammalian cell types and experimental situations create challenges for standard transfection experiments. The ViraPower Lentiviral Expression System overcomes these challenges with efficient vir...
Src cDNA Expression Kit (wild type)...
Homogenizing Solution, 18ml Proteinase K - [50ug/l] 75 l...
Biology Products: