Navigation Links
Yeast missing sex genes undergo unexpected sexual reproduction
Date:5/24/2009

DURHAM, N.C. An emerging form of the pathogenic yeast Candida is able to complete a full sexual cycle in a test tube, even though it's missing the genes for reproduction. And it may also do so while infecting us, according to Duke University Medical Center researchers.

"Sex contributes to the Candida yeast species' evolutionary success," said Joseph Heitman, M.D., Ph.D., director of the Center for Microbial Pathogenesis in the Duke Department of Molecular Genetics and Microbiology and co-author of two papers that tell the story in Nature and Current Biology. "I think the fact that it has a complete sex cycle is likely to play a role in the evolution of drug resistance in this emerging pathogenic yeast species. "

Yeast infections are notoriously hard to treat and yeast are one of the most successful pathogens and commensals in nature, he said. A commensal is an organism that benefits from associating with another organism without affecting the other. Humans are susceptible to three types of yeast infection: thrush (in the mouth and throat), vaginal infection, and a sometimes fatal systemic infection of bloodstream and organs, such as the kidney.

In a paper published online May 24 in Nature, Heitman's team reports that eight Candida species which have a sexual cycle were missing many of the genes related to reproduction found in other species.

"The unrecognized sex cycle could mean we need to develop new treatments to combat what is really happening in humans infected by yeast," said co-author Jennifer Reedy M.D. Ph.D.

With co-author Anna Floyd, Heitman and Reedy explored the question further in a study appearing in the May 14 Current Biology. The major question was: how could the yeast sexually produce spores when they lack so many genes responsible for meiosis, the process of sexual cell division that reduces chromosomes to half their number in the progeny?
'/>"/>

Contact: Mary Jane Gore
mary.gore@duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Jungle yeast
2. New study reveals the protein that makes phosphate chains in yeast
3. Rhythmic genomics -- the yeast metronome and the walk of life
4. Commercial yeasts upgraded with an enzyme for biofuel production
5. Scientists study full protein content of bakers yeast
6. Genetic differences between yeasts greater than those between humans and chimpanzees
7. Caltech engineers build mini drug-producing biofactories in yeast
8. Gene-environment interaction in yeast gene expression
9. University of Toronto scientists map entire yeast genome
10. UCI and CODA Genomics collaborate to re-engineer yeast for biofuel production
11. Fossil evidence of missing link in the origin of seals, sea lions, walruses found in Canadian Arctic
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... biomass burning burning forests to create agricultural ... agriculture and wildfires figures into both climate ... release of a new study by Stanford University ... the degree of that contribution had never been ... paper published July 30 in the Journal ...
(Date:7/31/2014)... State University researchers have completed a 20-year study ... Hills prairie at different times of the year. ... late spring time frame has no measurable negative ... have multiple benefits. , The study was conducted ... Prairie Biological Station fire chief, and Joseph Craine, ...
(Date:7/31/2014)... Neb., July 31, 2014 -- Do people make a ... mothers raise them that way? Is it a matter ... Nebraska-Lincoln and a colleague from Rice University say that ... some people lean left while others lean right. , ... and deep-seated psychology are at the core of political ...
Breaking Biology News(10 mins):Stanford professor finds that wildfires and other burns play bigger role in climate change 2Stanford professor finds that wildfires and other burns play bigger role in climate change 3Stanford professor finds that wildfires and other burns play bigger role in climate change 4Study finds benefits to burning Flint Hills prairie in fall and winter 2Study finds benefits to burning Flint Hills prairie in fall and winter 3Scientists find growing consensus: Political attitudes derive from body and mind 2
... research team has taken a major step forward in understanding ... immune response by combining nanotechnology and cell biology. T cells ... response to infection. Christopher Cairo and his team ... cell response is switched on. Cairo looked at the molecule ...
... of this campus activity is divided into three sessions: ... a patient,s perspective and embryology and ethics related to ... genetic counselors, molecular biologists, cytogeneticists, physicians, nurses, embryologists, patient ... find more information on this event here: http://www.eshre.eu/page.aspx/905 ...
... a molecular-scale version of ice fishing, a team of ... Technology (NIST) have developed methods to measure accurately the ... membranes. The "molecular rulers" they describe in a recent ... nanoporeswhose diameters on average are nearly 10,000 times smaller ...
Cached Biology News:U Alberta-led team studies T cell activation with nanoparticles 2Lollipops and ice fishing: Molecular rulers used to probe nanopores 2
(Date:8/1/2014)... August 01, 2014 Once a decision ... cost? This webinar will discuss how to define your ... Join speakers Bob Allen, Senior Director of Facilities Integration ... Engineering at Fluor Industrial Services, and special guest Carrier ... Planning at Amgen, as they provide an examination of ...
(Date:8/1/2014)... -- Cambrex Corporation (NYSE: CBM ) reports results ... Highlights , Second quarter sales increased 59% ... last year. , Second quarter EBITDA increased 86% to ... last year (see table at the end of this release). ... impact of foreign currency, to between 13% and 16% over ...
(Date:8/1/2014)... ON (PRWEB) August 01, 2014 ... has led to a better understanding embryonic development. ... and reorganize into structurally and functionally distinct tissues ... physical defects. Prof. Todd McDevitt, Melissa Kinney, ... biophysical signals interact with biochemical cues to control ...
(Date:7/31/2014)... August 01, 2014 “2014 ... Polyurethane Resin Industry” is a professional and ... The report introduces Polyurethane Resin basic information, ... chain structure and industry overview. This research ... domestic market as well as global industry ...
Breaking Biology Technology:Defining Low Cost in Your Solution for Future Facilities, New Webinar for Pharma, Biotech, Medical Device and Healthcare Companies, Hosted by Xtalks 2Cambrex Reports Second Quarter 2014 Financial Results 2Cambrex Reports Second Quarter 2014 Financial Results 3Cambrex Reports Second Quarter 2014 Financial Results 4Cambrex Reports Second Quarter 2014 Financial Results 5Cambrex Reports Second Quarter 2014 Financial Results 6Cambrex Reports Second Quarter 2014 Financial Results 7Cambrex Reports Second Quarter 2014 Financial Results 8Cambrex Reports Second Quarter 2014 Financial Results 9Cambrex Reports Second Quarter 2014 Financial Results 10Cambrex Reports Second Quarter 2014 Financial Results 11Cambrex Reports Second Quarter 2014 Financial Results 12Cambrex Reports Second Quarter 2014 Financial Results 13Cambrex Reports Second Quarter 2014 Financial Results 14Cambrex Reports Second Quarter 2014 Financial Results 15Cambrex Reports Second Quarter 2014 Financial Results 16Study Links Biomechanics and Gene Expression in Stem Cells 2Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 2Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 3Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 4
... (Nasdaq: TARG ) today announced the pricing of ... stock at a price,to the public of $10.00 per ... Targanta has granted to the underwriters a 30-day option ... stock at the initial,offering price, less underwriting discounts and ...
... (NSH), a,leading owner and operator of surgical hospitals ... majority stake in Sterling Ridge Surgery,Center, a freestanding ... NSH acquired its share of the fully ... intends to convert the facility,into a surgical hospital ...
... No Water, Produces Pure Glycerin, CHICAGO and ... biodiesel refining and distribution company, announced today,that it ... a novel solid catalyst that converts low-grade fats ... be located in Seymour,Ind., eliminates the need for ...
Cached Biology Technology:Targanta Therapeutics Announces Pricing of its Initial Public Offering 2National Surgical Hospitals Acquires Majority Share of Houston-Area Surgery Center 2New Benefuel Refinery Targets Key Flaws in Biodiesel Production 2New Benefuel Refinery Targets Key Flaws in Biodiesel Production 3
adult...
EPH electrode, cathode, 1. Category: Electrophoresis Systems & Standards & Reagents, IEF & SDS-PAGE & 2-D Electrophoresis, Multiphor II Kits & Components and Accessories....
GENOMIPHI V2 DNA AMP KIT 25RXN, 1 EA. Category: Genomics DNA Amplification....
GENOMIPHI HY KIT 1000 RXN, 1 EA. Category: Genomics DNA Amplification....
Biology Products: