Navigation Links
Wiley Prize in Biomedical Sciences awarded to Rosbash, Hall and Young
Date:1/31/2013

The 12th annual Wiley Prize in Biomedical Sciences has been awarded to Brandeis professors Michael Rosbash and Jeffrey Hall and their colleague Michael Young of Rockefeller University for the discovery of the molecular mechanisms governing circadian rhythms.

"The molecular network discovered by these researchers imparts cyclic behavior to many biological processes including sleep and wakefulness, metabolism and even the response to drugs," said Professor Gnter Blobel, chairman of the awards jury for the Wiley Prize and a 1999 Nobel Prize winner.

Their research could ultimately lead to the development of drugs to treat sleep disorders, physical and mental illness, and even jet lag.

Five previous Wiley Prize winners have gone on to win the Nobel Prize in either physiology or medicine.

Rosbash and Hall spent more than three decades at Brandeis collaboratively researching circadian rhythms, the biological clock which governs functions such as sleep and wakefulness, metabolism and hormone levels in organisms as simple as fruit flies and as complex as humans.

"We were incredibly fortunate to have advanced this problem in the remarkable way things have turned out," says Rosbash. "Jeff and I, as well as Mike Young at Rockefeller, began these studies in the fruit fly with no certainty in my case, no expectation that the fly clockworks would be essentially identical in humans. So our work not only turned out to be interesting but also potentially important. How lucky can three guys get?"

Their research uses the fruit fly Drosophila, a model organism valued for almost a century because of its relative genetic simplicity and its wide range of behaviors. At the molecular level, circadian rhythms use the same genes and are regulated in much the same way in all animals, including humans. Rosbash and Hall cloned the first Drosophila circadian clock gene in 1984.

"The discoveries they made in terms of identifying the first circadian clock genes is really a landmark in understanding how genes regulate behavior, and understanding our own 24-hour rhythms that seem to regulate so much of our biology," says Ravi Allada, professor and chair of the Department of Neurobiology at Northwestern University, who worked in the Rosbash Lab from 1995 to 2000.

Amita Sehgal, the John Herr Musser Professor of Neuroscience at the University of Pennsylvania and an investigator with the Howard Hughes Medical Institute, said the trio's groundbreaking research "opened up the whole field of circadian rhythms and inspired people like me to go into it."

"I'm really glad that they're getting recognized for it. It's a tremendous honor for them, but also for the field," said Sehgal, who worked as a post-doc in Young's lab at Rockefeller.

The Wiley Prize in Biomedical Sciences has recognized work that opens new fields of research or advanced novel concepts or their applications in a particular biomedical discipline.

This year's award will be presented to Rosbash, Hall and Dr. Young on April 5 at Rockefeller University in New York City.


'/>"/>

Contact: Susan Chaityn Lebovits
lebovits@brandies.edu
781-736-4027
Brandeis University
Source:Eurekalert  

Related biology news :

1. Physiological societies partner with Wiley on new open access journal
2. Wiley Partners with TED
3. British Ecological Society partners with Wiley open access journal Ecology and Evolution
4. Wiley signs collaboration agreement with the Asian Federation of Biotechnology
5. Wiley launches new interdisciplinary review WIREs Energy and Environment
6. Wiley-Blackwell launches new open-access journal: Food Science & Nutrition
7. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
8. Israel Prize awarded to Tel Aviv University biochemist
9. Brupbacher Prize goes to cancer researcher Michael Karin
10. 2 climate scientists win 2012 Vetlesen Prize for work on ozone hole, ice cores
11. Leibniz Prizes 2013: DFG honors 11 outstanding researchers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Wiley Prize in Biomedical Sciences awarded to Rosbash, Hall and Young
(Date:6/27/2016)... -- Research and Markets has announced the addition of ... their offering. The report forecasts ... grow at a CAGR of 12.28% during the period 2016-2020. ... market analysis with inputs from industry experts. The report covers the ... report also includes a discussion of the key vendors operating in ...
(Date:6/22/2016)... , June 22, 2016  The American College of ... Trade Show Executive Magazine as one of the fastest-growing ... May 25-27 at the Bellagio in Las Vegas ... the highest percentage of growth in each of the following ... exhibiting companies and number of attendees. The 2015 ACMG Annual ...
(Date:6/22/2016)... , June 22, 2016   ... management and verification solutions, has partnered with ... software solutions for Visitor Management, Self-Service Kiosks ... provides products that add functional enhancements to ... provides corporations and venues with an automated ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the ... the Supplyframe Design Lab . Located in Pasadena, Calif., the Design Lab’s ... how hardware projects are designed, built and brought to market. , The Design ...
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... and technical consulting, provides a free webinar on Performing Quality Investigations: ... 2016 at 12pm CT at no charge. , Incomplete investigations are still a ...
(Date:6/22/2016)... DIEGO , June 22, 2016 ... that will allow them to produce up to ... from one lot within one week. These high-quality, ... time laboriously preparing cells and spend more time ... possible through a proprietary, high-volume manufacturing process that ...
Breaking Biology Technology: